product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody
catalog :
NBP1-06640H
quantity :
0.1 ml
price :
319.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
Catalog Number :
NBP1-06640H
Product Name :
Rabbit Polyclonal Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody
List Price :
319.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
EC 1.14.11, EC 1.14.11.-, JmjC domain-containing protein 3, JMJD3lysine-specific demethylase 6B, jumonji domain containing 3, histone lysine demethylase, Jumonji domain-containing protein 3, KIAA0346jumonji domain containing 3, lysine (K)-specific demethylase 6B, Lysine demethylase 6B
Background :
JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.
Buffer :
PBS
Clonality :
Polyclonal
Conjugate :
HRP
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
Synthetic peptide made to an internal portion of the mouse JMJD3 protein (within residues 600-650). [Swiss-Prot# Q5NCY0]
Localization :
Nucleus (probable)
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human and mouse. 100% sequence identity with rat protein.
Storage :
Store at 4C in the dark.
Uses :
This JMJD3 antibody is useful for Western Blot where a band is seen at ~ 180 kDa. This antibody is not applicable for Immunocytochemistry. Use in FLOW was reported in scientific literature (PMID: 23772023).
Research Area :
Cancer, Chromatin Research, Transcription Factors and Regulators
more info or order :
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.