GRP78/HSPA5 Antibody - BSA Free | Novus Biologicals NBP1-06274 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

GRP78/HSPA5 Antibody - BSA Free

catalog :

NBP1-06274

quantity :

0.1 ml (also 0.025 ml)

price :

459 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken, bovine, zebrafish , roundworm

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 28

Reference
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Shrestha S, Erikson G, Lyon J, Spigelman A, Bautista A, Manning Fox J, et al. Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress. Sci Adv. 2022;8:eabo3932 pubmed publisher
Lemoine H, Raud L, Foulquier F, Sayer J, Lambert B, Olinger E, et al. Monoallelic pathogenic ALG5 variants cause atypical polycystic kidney disease and interstitial fibrosis. Am J Hum Genet. 2022;109:1484-1499 pubmed publisher
Aggarwal P, Liu Z, Cheng G, Singh S, Shi C, Chen Y, et al. Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila. Cell Rep. 2022;39:110958 pubmed publisher
Li Q, Fan X, Lu W, Sun C, Pei Z, Zhang M, et al. Novel NPR2 Gene Mutations Affect Chondrocytes Function via ER Stress in Short Stature. Cells. 2022;11: pubmed publisher
Chen X, Li Z, Lv Y, Han Y, Qu X, Zhang Y, et al. Comparative proteomic identification of capacitated and non-capacitated sperm of Yanbian Yellow Cattle. Theriogenology. 2022;186:12-20 pubmed publisher
Yuan X, Shen Q, Ma W. Long Noncoding RNA Hotair Promotes the Progression and Immune Escape in Laryngeal Squamous Cell Carcinoma through MicroRNA-30a/GRP78/PD-L1 Axis. J Immunol Res. 2022;2022:5141426 pubmed publisher
Rudalska R, Harbig J, Snaebjornsson M, Klotz S, Zwirner S, Taranets L, et al. LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer. Nat Cancer. 2021;2:201-217 pubmed publisher
Rossin F, Avitabile E, Catarinella G, Fornetti E, Testa S, Oliverio S, et al. Reticulon-1C Involvement in Muscle Regeneration. Metabolites. 2021;11: pubmed publisher
Stojkovska I, Wani W, Zunke F, Belur N, Pavlenko E, Mwenda N, et al. Rescue of α-synuclein aggregation in Parkinson's patient neurons by synergistic enhancement of ER proteostasis and protein trafficking. Neuron. 2021;: pubmed publisher
Arquier N, Bjordal M, Hammann P, Kuhn L, Leopold P. Brain adiponectin signaling controls peripheral insulin response in Drosophila. Nat Commun. 2021;12:5633 pubmed publisher
Shastri S, Shinde T, Woolley K, Smith J, Gueven N, Eri R. Short-Chain Naphthoquinone Protects Against Both Acute and Spontaneous Chronic Murine Colitis by Alleviating Inflammatory Responses. Front Pharmacol. 2021;12:709973 pubmed publisher
VerPlank J, Gawron J, Silvestri N, Feltri M, Wrabetz L, Goldberg A. Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy. Brain. 2021;: pubmed publisher
Li L, Zhong J, Li M, Sun Y, Niu Y, Wu C, et al. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure. Biomed Res Int. 2021;2021:8569921 pubmed publisher
Nam Y, Kong D, Wang D, Orfali R, Sherpa R, Totonchy J, et al. Differential modulation of SK channel subtypes by phosphorylation. Cell Calcium. 2021;94:102346 pubmed publisher
Arioka Y, Shishido E, Kushima I, Suzuki T, Saito R, Aiba A, et al. Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons. EBioMedicine. 2021;63:103138 pubmed publisher
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Chou C, Yang R, Chan L, Li C, Sun L, Lee H, et al. The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer. Am J Cancer Res. 2020;10:2621-2634 pubmed
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image

image 1 :

Simple Western: GRP78/HSPA5 Antibody [NBP1-06274] - Image shows a specific band for GRP78 in 0.1 mg/mL of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NBP1-06274

SKU :

NBP1-06274

product name :

GRP78/HSPA5 Antibody - BSA Free

description :

The GRP78/HSPA5 Antibody - BSA Free from Novus Biologicals is a rabbit polyclonal antibody to GRP78/HSPA5. This antibody reacts with bovine,c. elegans,chicken,drosophila,drosophilia,human,insect - drosophila,mouse,rat,sheep,zebrafish,fish - danio rerio (zebrafish),nematode - caenorhabditis elegans. The GRP78/HSPA5 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Simple Western,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence.

target :

GRP78/HSPA5

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic peptide made to an internal portion of human GRP78 (within residues 250-300). [Swiss-Prot# P11021]

isotype :

IgG

marker :

ER Stress Marker

purity :

Immunogen affinity purified

species :

Bovine,C. elegans,Chicken,Drosophila,Drosophilia,Human,Mouse,Rat,Sheep,Zebrafish

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

theoretical molecular weight :

78 kDa

gene symbol :

HSPA5

Antibody validation :

Biological Validation

applications :

Immunohistochemistry,Simple Western,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence

USD :

459

USD 2025 :

459 USD

alt names :

78 kDa glucose-regulated protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, FLJ26106, GRP-78, GRP78BIP, Heat shock 70 kDa protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), Immunoglobulin heavy chain-binding protein, MIF2

more info or order :

Novus Biologicals product webpage