product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DIO3 Antibody - BSA Free
catalog :
NBP1-05767
quantity :
0.1 ml (also 0.025 ml)
price :
419 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay
more info or order :
citations: 11
Reference
Lavecchia A, Mantzouratou P, Cerullo D, Locatelli M, Conti S, Tironi M, et al. Thyroid hormone treatment counteracts cellular phenotypical remodeling in diabetic organs. iScience. 2023;26:107826 pubmed publisher
Peluso T, Nittoli V, Reale C, Porreca I, Russo F, Roberto L, et al. Chronic Exposure to Chlorpyrifos Damages Thyroid Activity and Imbalances Hepatic Thyroid Hormones Signaling and Glucose Metabolism: Dependency of T3-FOXO1 Axis by Hyperglycemia. Int J Mol Sci. 2023;24: pubmed publisher
Kohon M, Zaaroor Levy M, Hornik Lurie T, Shalom A, Berl A, Drucker L, et al. αvβ3 Integrin as a Link between the Development of Fibrosis and Thyroid Hormones in Systemic Sclerosis. Int J Mol Sci. 2023;24: pubmed publisher
Salas Lucia F, Fekete C, Sink xf3 R, Egri P, Rada K, Ruska Y, et al. Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain. elife. 2023;12: pubmed publisher
Agarwal S, Koh K, Tardi N, Chen C, Dande R, WerneckdeCastro J, et al. Deiodinase-3 is a thyrostat to regulate podocyte homeostasis. EBioMedicine. 2021;72:103617 pubmed publisher
Devalraju K, Tripathi D, Neela V, Paidipally P, Radhakrishnan R, Singh K, et al. Reduced thyroxine production in young household contacts of tuberculosis patients increases active tuberculosis disease risk. JCI Insight. 2021;6: pubmed publisher
Benedetti V, Lavecchia A, Locatelli M, Brizi V, Corna D, Todeschini M, et al. Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes. JCI Insight. 2019;4: pubmed publisher
Pörings A, Lowin T, Dufner B, Grifka J, Straub R. A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients. Sci Rep. 2019;9:13235 pubmed publisher
Calonne J, Isacco L, Miles Chan J, Arsenijevic D, Montani J, Guillet C, et al. Reduced Skeletal Muscle Protein Turnover and Thyroid Hormone Metabolism in Adaptive Thermogenesis That Facilitates Body Fat Recovery During Weight Regain. Front Endocrinol (Lausanne). 2019;10:119 pubmed publisher
Nascimento B, Bocco B, Fernandes G, Fonseca T, McAninch E, Cardoso C, et al. Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice. Endocrinology. 2018;159:3090-3104 pubmed publisher
Yamauchi I, Sakane Y, Yamashita T, Hirota K, Ueda Y, Kanai Y, et al. Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans. Endocrine. 2018;59:353-363 pubmed publisher
image
image 1 :
Novus Biologicals NBP1-05767 image 1
Western Blot: DIO3 Antibody [NBP1-05767] - Detection of Dio3 in rat placenta.
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP1-05767
SKU :
NBP1-05767
product name :
DIO3 Antibody - BSA Free
description :
The DIO3 Antibody - BSA Free from Novus Biologicals is a rabbit polyclonal antibody to DIO3. This antibody reacts with hamster,human,mouse,rabbit,rat. The DIO3 Antibody - BSA Free has been validated for the following applications: Flow Cytometry,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence.
target :
DIO3
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide made to an internal portion of rat DIO3 (within residues 250-300). [Swiss-Prot# P49897]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Hamster,Human,Mouse,Rabbit,Rat
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
31 kDa
gene symbol :
DIO3
applications :
Flow Cytometry,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence
USD :
399
USD 2025 :
419 USD
alt names :
5DIII, D3, deiodinase, iodothyronine, type III, DIOIII, EC 1.97.1, EC 1.97.1.11, ITDI3, placental type, thyroxine deiodinase type III (selenoprotein), Type 3 DI, type 3 iodothyronine selenodeiodinase, type III iodothyronine deiodinase, type-III 5' deiodinase, Type-III 5'-deiodinase
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.