product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GFAP Antibody
catalog :
NBP1-05198
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 38
Reference
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Peng L, Liu S, Xu J, Xie W, Fang X, Xia T, et al. Metformin alleviates prolonged isoflurane inhalation induced cognitive decline via reducing neuroinflammation in adult mice. Int Immunopharmacol. 2022;109:108903 pubmed publisher
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Boutin M, Strong C, Van Hese B, Hu X, Itkin Z, Chen Y, et al. A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids. SLAS Discov. 2022;27:209-218 pubmed publisher
Cole J, Sarabia Del Castillo J, Gut G, Gonzalez Bohorquez D, Pelkmans L, Jessberger S. Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging. elife. 2022;11: pubmed publisher
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Morales J, De A, Miller A, Chen Z, McCarty J. Mlc1-Expressing Perivascular Astrocytes Promote Blood-Brain Barrier Integrity. J Neurosci. 2022;42:1406-1416 pubmed publisher
Khan S, Sobu Y, Dhekne H, Tonelli F, Berndsen K, Alessi D, et al. Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain. elife. 2021;10: pubmed publisher
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Logan T, Simon M, Rana A, Cherf G, Srivastava A, Davis S, et al. Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic. Cell. 2021;184:4651-4668.e25 pubmed publisher
Chen H, Kevala K, Aflaki E, Marugan J, Kim H. GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice. J Neuroinflammation. 2021;18:157 pubmed publisher
Mausner Fainberg K, Benhamou M, Golan M, Kimelman N, Danon U, Marom E, et al. Specific Blockade of Bone Morphogenetic Protein-2/4 Induces Oligodendrogenesis and Remyelination in Demyelinating Disorders. Neurotherapeutics. 2021;18:1798-1814 pubmed publisher
Li J, Tian M, Hua T, Wang H, Yang M, Li W, et al. Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain. Autophagy. 2021;:1-21 pubmed publisher
Niehaus J, Taylor Blake B, Loo L, Simon J, Zylka M. Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury. Neuron. 2021;109:1274-1282.e6 pubmed publisher
Tao K, Cai Q, Zhang X, Zhu L, Liu Z, Li F, et al. Astrocytic histone deacetylase 2 facilitates delayed depression and memory impairment after subarachnoid hemorrhage by negatively regulating glutamate transporter-1. Ann Transl Med. 2020;8:691 pubmed publisher
Liu Z, Murphy S, Wong L, Schaeffer A, Thumbikat P. Neuronal/astrocytic expression of chemokine (C-C motif) ligand 2 is associated with monocyte/macrophage recruitment in male chronic pelvic pain. Pain. 2020;161:2581-2591 pubmed publisher
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Zhang Y, Zhang Y, Wu R, Gao F, Zang P, Hu X, et al. Effect of cerebral small vessel disease on cognitive function and TLR4 expression in hippocampus. J Clin Neurosci. 2019;67:210-214 pubmed publisher
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Dhekne H, Yanatori I, Gomez R, Tonelli F, Diez F, Schule B, et al. A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. elife. 2018;7: pubmed publisher
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image
image 1 :
Novus Biologicals NBP1-05198 image 1
Immunohistochemistry Free-Floating: GFAP Antibody [NBP1-05198] - Staining of a section of mouse hippocampus stained with chicken pAb to GFAP, NBP1-05198, dilution 1:5000 in green and costained with rabbit pAb to FOX3/NeuN, dilution 1:5000, in red. The blue is DAPI staining of nuclear DNA. Following transcardial perfusion with 4% paraformaldehyde, mouse brain was post fixed for 24 hours, cut to 45 uM, and free-floating sections were stained with the above antibodies. The GFAP antibody stains a network of astroglial cells while the Fox3/NeuN antibody stains the nuclei and proximal perikarya of neurons.
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP1-05198
SKU :
NBP1-05198
product name :
GFAP Antibody
description :
The GFAP Antibody from Novus Biologicals is a chicken polyclonal antibody to GFAP. This antibody reacts with bovine,equine,human,mouse,porcine,rat. The GFAP Antibody has been validated for the following applications: Immunohistochemistry Free-Floating,IF/IHC,IHC-F,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Multiplex Immunoassay,Immunocytochemistry/ Immunofluorescence.
target :
GFAP
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
Supplied as concentrated total IgY preparation from egg yolk. Exact concentration of target specific IgY is not quantifiable as the preparation contains both immune IgY specific for the target and also irrelevant, non-immune IgY.
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Chicken
immunogen :
This GFAP Antibody was developed against recombinant full length human GFAP isotype 1 expressed in and purified from E. coli.
isotype :
IgY
marker :
Astrocyte Marker
purity :
IgY purified
species :
Bovine,Equine,Human,Mouse,Porcine,Rat
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
50 kDa
gene symbol :
GFAP
accessionNumbers :
Q28115
applications :
Immunohistochemistry Free-Floating,IF/IHC,IHC-F,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Multiplex Immunoassay,Immunocytochemistry/ Immunofluorescence
USD :
399
USD 2025 :
409 USD
alt names :
ALXDRD, FLJ45472, GFAP, GFAP astrocytes, glial fibrillary acidic protein
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.