GFAP Antibody (5C10) | Novus Biologicals NBP1-05197 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

GFAP Antibody (5C10)

catalog :

NBP1-05197

quantity :

0.1 ml (also 0.025 ml)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5c10

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 27

Reference
Jahnke L, Perrenoud V, Zandi S, Li Y, Conedera F, Enzmann V. Modulation of Extracellular Matrix Composition and Chronic Inflammation with Pirfenidone Promotes Scar Reduction in Retinal Wound Repair. Cells. 2024;13: pubmed publisher
Duan Q, Zhang Q, Nie K, Huang R, Yang J, He P, et al. Myo1d promotes alpha-synuclein transfer from brain microvascular endothelial cells to pericytes through tunneling nanotubes. iScience. 2023;26:107458 pubmed publisher
Rueda Gensini L, Serna J, Rubio D, Orozco J, Bola xf1 os N, Cruz J, et al. Three-dimensional neuroimmune co-culture system for modeling Parkinson's disease microenvironmentsin vitro. Biofabrication. 2023;15: pubmed publisher
Jahnke L, Zandi S, Elhelbawi A, Conedera F, Enzmann V. Characterization of Macroglia Response during Tissue Repair in a Laser-Induced Model of Retinal Degeneration. Int J Mol Sci. 2023;24: pubmed publisher
Tseng K, Stratoulias V, Hu W, Wu J, Wang V, Chen Y, et al. Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage. Cell Death Dis. 2023;14:128 pubmed publisher
Wong J, Lin J, Kung N, Tse A, Shimshak S, Roselle A, et al. Cerebrospinal fluid immunoglobulins in primary progressive multiple sclerosis are pathogenic. Brain. 2023;146:1979-1992 pubmed publisher
Griflyuk A, Postnikova T, Zaitsev A. Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats. Int J Mol Sci. 2022;23: pubmed publisher
Becker Krail D, Ketchesin K, Burns J, Zong W, Hildebrand M, Depoy L, et al. Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior. Biol Psychiatry. 2022;92:68-80 pubmed publisher
Scaricamazza S, Salvatori I, Amadio S, Nesci V, Torcinaro A, Giacovazzo G, et al. Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1G93A mice. Br J Pharmacol. 2022;179:1732-1752 pubmed publisher
Postnikova T, Diespirov G, Amakhin D, Vylekzhanina E, Soboleva E, Zaitsev A. Impairments of Long-Term Synaptic Plasticity in the Hippocampus of Young Rats during the Latent Phase of the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy. Int J Mol Sci. 2021;22: pubmed publisher
Fayaz M, Rosa G, Honaramooz A. Neonatal Porcine Germ Cells Dedifferentiate and Display Osteogenic and Pluripotency Properties. Cells. 2021;10: pubmed publisher
Zhan H, Wang Y, Yu S, Cai G, Zeng Y, Ma J, et al. Upregulation of Mlxipl induced by cJun in the spinal dorsal horn after peripheral nerve injury counteracts mechanical allodynia by inhibiting neuroinflammation. Aging (Albany NY). 2020;12:11004-11024 pubmed publisher
Alshammari T, Alghamdi H, Green T, Niazy A, Alkahdar L, Alrasheed N, et al. Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions. PLoS ONE. 2019;14:e0222818 pubmed publisher
Yazdankhah M, Shang P, Ghosh S, Bhutto I, Stepicheva N, Grebe R, et al. Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease. Autophagy. 2020;16:1130-1142 pubmed publisher
Sivaguru M, Khaw Y, Inoue M. A Confocal Reflection Super-Resolution Technique to Image Golgi-Cox Stained Neurons. J Microsc. 2019;275:115-130 pubmed publisher
Murakami T, Miyoshi T, Takahashi N, Kangawa A. Persistent hyperplastic primary vitreous in two piglets. J Vet Med Sci. 2019;81:357-360 pubmed publisher
Lananna B, Nadarajah C, Izumo M, Cedeno M, Xiong D, Dimitry J, et al. Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1. Cell Rep. 2018;25:1-9.e5 pubmed publisher
Hwang S, Ham S, Lee S, Lee Y, Lee G. Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons. Neurotoxicology. 2018;65:221-230 pubmed publisher
Filice F, Celio M, Babalian A, Blum W, Szabolcsi V. Parvalbumin-expressing ependymal cells in rostral lateral ventricle wall adhesions contribute to aging-related ventricle stenosis in mice. J Comp Neurol. 2017;525:3266-3285 pubmed publisher
Jurga A, Piotrowska A, Makuch W, Przewlocka B, Mika J. Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model. Front Pharmacol. 2017;8:48 pubmed publisher
Pacheco Quinto J, Eckman C, Eckman E. Major amyloid-Î²-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex. Neurobiol Aging. 2016;48:83-92 pubmed publisher
Bang Y, Kim K, Seol W, Choi H. LRRK2 interferes with aggresome formation for autophagic clearance. Mol Cell Neurosci. 2016;75:71-80 pubmed publisher
Nemery E, Gabriel A, Piret J, Antoine N. Nociceptive and sympathetic innervations in the abaxial part of the cranial horn of the equine medial meniscus: an immunohistochemical approach. J Anat. 2016;229:791-799 pubmed publisher
Gebremedhin D, Zhang D, Carver K, Rau N, Rarick K, Roman R, et al. Expression of CYP 4A ?-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes. Prostaglandins Other Lipid Mediat. 2016;124:16-26 pubmed publisher
Szabolcsi V, Celio M. De novo expression of parvalbumin in ependymal cells in response to brain injury promotes ependymal remodeling and wound repair. Glia. 2015;63:567-94 pubmed publisher
Brai E, Marathe S, Zentilin L, Giacca M, Nimpf J, Kretz R, et al. Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviour. Eur J Neurosci. 2014;40:3436-49 pubmed publisher
Hernandez C, Cortez I, Gu Z, Colón Sáez J, Lamb P, Wakamiya M, et al. Research tool: Validation of floxed ?7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches. J Physiol. 2014;592:3201-14 pubmed publisher

image

image 1 :

Immunohistochemistry Free-Floating: GFAP Antibody (5C10) [NBP1-05197] - Analysis of rat cerebellum section stained with mouse GFAP mAb, dilution 1:1,000 (Green), costained with rabbit neurofilament NF-L pAb, dilution 1:2,000 (Red). Following transcardial perfusion with 4% paraformaldehyde, brain was post fixed for 24hrs, cut to 45uM, and free-floating sections were stained with antibodies. The GFAP antibody stains a network of astroglial cells, while the NF-L antibody labels neuronal cells and their processes.

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NBP1-05197

SKU :

NBP1-05197

product name :

GFAP Antibody (5C10)

description :

The GFAP Antibody (5C10) from Novus Biologicals is a mouse monoclonal antibody to GFAP. This antibody reacts with bovine,equine,human,mouse,porcine,rat. The GFAP Antibody (5C10) has been validated for the following applications: Immunohistochemistry Free-Floating,Simple Western,IF/IHC,IHC/IF,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Block/Neutralize,Immunocytochemistry/ Immunofluorescence.

target :

GFAP

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS, 50% glycerol

clonality :

Monoclonal

clone :

5C10

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This GFAP Antibody (5C10) was developed against a preparation of purified pig spinal cord GFAP

isotype :

IgG1

marker :

Astrocyte Marker

purity :

Immunogen affinity purified

species :

Bovine,Equine,Human,Mouse,Porcine,Rat

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

theoretical molecular weight :

50 kDa

gene symbol :

GFAP

applications :

Immunohistochemistry Free-Floating,Simple Western,IF/IHC,IHC/IF,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Block/Neutralize,Immunocytochemistry/ Immunofluorescence

USD :

469

USD 2025 :

489 USD

alt names :

ALXDRD, FLJ45472, GFAP, GFAP astrocytes, glial fibrillary acidic protein

more info or order :

Novus Biologicals product webpage