product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
alpha-Synuclein Antibody (2A7)
catalog :
NBP1-05194
quantity :
0.1 ml (also 0.025 ml)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2A7
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 6
Reference
Rueda Gensini L, Serna J, Rubio D, Orozco J, Bola xf1 os N, Cruz J, et al. Three-dimensional neuroimmune co-culture system for modeling Parkinson's disease microenvironmentsin vitro. Biofabrication. 2023;15: pubmed publisher
Amireddy N, Dulam V, Kaul S, Pakkiri R, Kalivendi S. The mitochondrial uncoupling effects of nitazoxanide enhances cellular autophagy and promotes the clearance of α-synuclein: Potential role of AMPK-JNK pathway. Cell Signal. 2023;109:110769 pubmed publisher
Leupold L, Sigutova V, Gerasimova E, Regensburger M, Zundler S, Zunke F, et al. The Quest for Anti-α-Synuclein Antibody Specificity-Lessons Learnt From Flow Cytometry Analysis. Front Neurol. 2022;13:869103 pubmed publisher
Liu X, Balaraman K, Lynch C, Hebron M, Shah P, Hu S, et al. Inhibition of Ubiquitin-Specific Protease-13 Improves Behavioral Performance in Alpha-Synuclein Expressing Mice. Int J Mol Sci. 2022;23: pubmed publisher
Kim Y, Stahl M, Huang X, Connor J. H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity. J Neurochem. 2020;: pubmed publisher
Lv R, Du L, Liu X, Zhou F, Zhang Z, Zhang L. Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease. Life Sci. 2019;223:158-165 pubmed publisher
image
image 1 :
Novus Biologicals NBP1-05194 image 1
Immunohistochemistry Free-Floating: alpha-Synuclein Antibody (2A7) [NBP1-05194] - Analysis of rat cerebellum section costained with mouse mAb to alpha-synuclein NBP1-05194, dilution 1:1,000, in red, and rabbit pAb to GFAP, dilution 1:5,000 in green. The blue is DAPI staining of nuclear DNA. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45uM, and free-floating sections were stained with above antibodies. The alpha-synuclein protein is concentrated in synaptic regions, while the GFAP antibody stains the filamentous cytoskeleton of Bergmann glia and astrocytic cells.
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP1-05194
SKU :
NBP1-05194
product name :
alpha-Synuclein Antibody (2A7)
description :
The alpha-Synuclein Antibody (2A7) from Novus Biologicals is a mouse monoclonal antibody to alpha-Synuclein. This antibody reacts with bovine,human,mouse,porcine,rat. The alpha-Synuclein Antibody (2A7) has been validated for the following applications: Immunohistochemistry,Immunohistochemistry Free-Floating,Simple Western,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
alpha-Synuclein
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
50% PBS, 50% glycerol
clonality :
Monoclonal
clone :
2A7
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This alpha-Synuclein Antibody (2A7) was developed against full length human recombinant protein with the epitope from amino acids 61-95.
isotype :
IgG1
purity :
Immunogen affinity purified
species :
Bovine,Human,Mouse,Porcine,Rat
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
15 kDa
gene symbol :
SNCA
accessionNumbers :
P37840
applications :
Immunohistochemistry,Immunohistochemistry Free-Floating,Simple Western,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
449
USD 2025 :
479 USD
alt names :
alpha-synuclein, I+/--synuclein, MGC110988, NACP, non A-beta component of AD amyloid, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK1, PARK4, PD1, SNCA, synuclein alpha-140, synuclein, alpha (non A4 component of amyloid precursor), truncated alpha synuclein
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.