MafA Antibody | Novus Biologicals NBP1-00121 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MafA Antibody

catalog :

NBP1-00121

quantity :

0.1 ml

price :

479 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s1c	Spaeth J, Gupte M, Perelis M, Yang Y, CYPHERT H, Guo S, et al. Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning. Diabetes. 2017;66:2830-2839 pubmed publisher
	Liu Y, Kepple J, Shalev A, S Hunter C. LDB1-mediated transcriptional complexes are sensitive to islet stress. Islets. 2022;14:58-68 pubmed publisher
	Walker E, Cha J, Tong X, Guo M, Liu J, Yu S, et al. Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males. Cell Rep. 2021;37:109813 pubmed publisher
	Yang X, Graff S, Heiser C, Ho K, Chen B, Simmons A, et al. Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response. Diabetes. 2020;69:1219-1231 pubmed publisher
	Shrestha N, Liu T, Ji Y, Reinert R, Torres M, Li X, et al. Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling. J Clin Invest. 2020;130:3499-3510 pubmed publisher
	Gomez R, Wawro P, Lis P, Alessi D, Pfeffer S. Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases. J Cell Biol. 2019;218:4157-4170 pubmed publisher
	Jaafar R, Tran S, Shah A, Sun G, Valdearcos M, Marchetti P, et al. mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes. J Clin Invest. 2019;130:4124-4137 pubmed publisher
	Spaeth J, Liu J, Peters D, Guo M, Osipovich A, Mohammadi F, et al. The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function. Diabetes. 2019;: pubmed publisher
	Wade A, Liu Y, Bethea M, Toren E, Tse H, Hunter C. LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function. J Biol Chem. 2019;294:11728-11740 pubmed publisher
	Wilson C, Spaeth J, Karp J, Stocks B, Hoopes E, Stein R, et al. B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib. JCI Insight. 2019;5: pubmed publisher
	Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, et al. Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7. EMBO Mol Med. 2019;11: pubmed publisher
	Vukotic M, Nolte H, König T, Saita S, Ananjew M, Kruger M, et al. Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Mol Cell. 2017;67:471-483.e7 pubmed publisher
	Diokmetzidou A, Soumaka E, Kloukina I, Tsikitis M, Makridakis M, Varela A, et al. Desmin and ?B-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival. J Cell Sci. 2016;129:3705-3720 pubmed
	Wrobel L, Sokol A, Chojnacka M, Chacinska A. The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly. Sci Rep. 2016;6:27484 pubmed publisher
	Nguyen N, Now H, Kim W, Kim N, Yoo J. Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform. Sci Rep. 2016;6:23377 pubmed publisher
	Conrad E, Dai C, Spaeth J, Guo M, Cyphert H, Scoville D, et al. The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. Am J Physiol Endocrinol Metab. 2016;310:E91-E102 pubmed publisher
	Li L, Gao G, Shankar J, Joshi B, Foster L, Nabi I. p38 MAP kinase-dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER-mitochondria association and mitochondria motility. Mol Biol Cell. 2015;26:3828-40 pubmed publisher
	Scoville D, Cyphert H, Liao L, Xu J, Reynolds A, Guo S, et al. MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet Î²-Cell Function. Diabetes. 2015;64:3772-83 pubmed publisher
	Park S, Jeong J, Park Y, Park K, Lee H, Lee N, et al. Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics. Sci Rep. 2015;5:8694 pubmed publisher

product information

brand :

Novus

master code :

NBP1-00121

SKU :

NBP1-00121

product name :

MafA Antibody

description :

The MafA Antibody from Novus Biologicals is a rabbit polyclonal antibody to MafA. This antibody reacts with human, mouse. The MafA Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

target :

MafA

category :

Primary Antibodies

sizes available :

0.1 ml

buffer :

TBS and 0.1% BSA

clonality :

Polyclonal

concentration :

0.05 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residue 300 and the C-terminus (residue 359) of mouse v-maf musculoaponeurotic fibrosarcoma oncogene homolog A using the numbering given in entry NP_919331.1 (GeneID 378435).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human, Mouse

gene symbol :

MAFA

accessionNumbers :

NP_919331.1

applications :

Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

USD :

464

USD 2023 :

479 USD

alt names :

hMafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3B1, transcription factor MafA, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage