product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DLL4 Antibody
catalog :
NB600-892
quantity :
0.1 mg (also 0.025 mg)
price :
499 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Kim D, Park G, Huuhtanen J, Lundgren S, Khajuria R, Hurtado A, et al. Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease. Nat Commun. 2020;11:2246 pubmed publisher
Baek M, Ahn C, Cho H, Choi J, Son K, Yoon M. Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation. Sci Rep. 2019;9:14910 pubmed publisher
Yao H, Tang H, Zhang Y, Zhang Q, Liu X, Liu Y, et al. DEPTOR inhibits cell proliferation and confers sensitivity to dopamine agonist in pituitary adenoma. Cancer Lett. 2019;459:135-144 pubmed publisher
Shao L, Sottoriva K, Palasiewicz K, Zhang J, Hyun J, Soni S, et al. A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche. Haematologica. 2019;: pubmed publisher
Zheng X, Narayanan S, Sunkari V, Eliasson S, Botusan I, Grunler J, et al. Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes. Proc Natl Acad Sci U S A. 2019;116:6985-6994 pubmed publisher
Suryawan A, Davis T. Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation. J Nutr. 2018;148:825-833 pubmed publisher
Caron A, Mouchiroud M, Gautier N, Labbé S, Villot R, Turcotte L, et al. Loss of hepatic DEPTOR alters the metabolic transition to fasting. Mol Metab. 2017;6:447-458 pubmed publisher
Davis R, Kechele D, Blakeney E, Pawlak J, Caron K. Lymphatic deletion of calcitonin receptor-like receptor exacerbates intestinal inflammation. JCI Insight. 2017;2:e92465 pubmed publisher
Kontomanolis E, Mitrakas A, Giatromanolaki A, Kareli D, Panteliadou M, Pouliliou S, et al. A pilot study on plasma levels of micro-RNAs involved in angiogenesis and vascular maturation in patients with breast cancer. Med Oncol. 2017;34:20 pubmed publisher
Song H, Yoon M. PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639. Sci Rep. 2016;6:36968 pubmed publisher
Muguruma Y, Hozumi K, Warita H, Yahata T, Uno T, Ito M, et al. Maintenance of Bone Homeostasis by DLL1-Mediated Notch Signaling. J Cell Physiol. 2017;232:2569-2580 pubmed publisher
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
Caron A, Labbé S, Lanfray D, Blanchard P, Villot R, Roy C, et al. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity. Mol Metab. 2016;5:102-112 pubmed publisher
Caron A, Baraboi E, Laplante M, Richard D. DEP domain-containing mTOR-interacting protein in the rat brain: distribution of expression and potential implication. J Comp Neurol. 2015;523:93-107 pubmed publisher
product information
brand :
Novus
master code :
NB600-892
SKU :
NB600-892
product name :
DLL4 Antibody
description :
The DLL4 Antibody from Novus Biologicals is a rabbit polyclonal antibody to DLL4. This antibody reacts with human, mouse, rat. The DLL4 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
target :
DLL4
category :
Primary Antibodies
sizes available :
0.1 mg (also 0.025 mg)
buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
DLL4 Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Human DLL4. (Uniprot: Q9NR61)
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat
theoretical molecular weight :
74.6 kDa
gene symbol :
DLL4
accessionNumbers :
Q9NR61
applications :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
USD :
485
USD 2023 :
499 USD
alt names :
delta 4, Delta 4 precursor, delta ligand 4, delta4, delta-like 4 (Drosophila), delta-like 4 homolog, delta-like 4 homolog (Drosophila), delta-like 4 protein, delta-like protein 4, Drosophila Delta homolog 4, hdelta2, MGC126344, notch ligand delta-2, notch ligand DLL4
storage :
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.