product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TNF-alpha Antibody - Azide Free
catalog :
NB600-587
quantity :
0.2 ml (also 0.04 ml)
price :
329 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
L243
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, blocking or activating experiments
more info or order :
citations: 42
Published Application/Species/Sample/Dilution | Reference |
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| Chen J, Jian D, Lien C, Lin Y, Ting C, Chen L, et al. Adipocytes play an etiological role in the podocytopathy of high-fat diet-fed rats. J Endocrinol. 2016;231:109-120 pubmed
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Gunel C, Demirci B, Eryilmaz A, Yilmaz M, Meteoglu I, Omurlu I, et al. Inhibitory Effect of Pycnogenol® on Airway Inflammation in Ovalbumin-Induced Allergic Rhinitis. Balkan Med J. 2016;33:620-626 pubmed
| |
Apps R, Murphy S, Fernando R, Gardner L, Ahad T, Moffett A. Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies. Immunology. 2009;127:26-39 pubmed publisher
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Wahlstrom J, Dengjel J, Persson B, Duyar H, Rammensee H, Stevanovic S, et al. Identification of HLA-DR-bound peptides presented by human bronchoalveolar lavage cells in sarcoidosis. J Clin Invest. 2007;117:3576-82 pubmed
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Setterblad N, Garban F, Weigl R, Assier E, Drillat P, Charron D, et al. Extracorporeal photophoresis increases sensitivity of monocytes from patients with graft-versus-host disease to HLA-DR-mediated cell death. Transfusion. 2008;48:169-77 pubmed
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Dengjel J, Schoor O, Fischer R, Reich M, Kraus M, Müller M, et al. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci U S A. 2005;102:7922-7 pubmed
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Ovsyannikova I, Johnson K, Naylor S, Poland G. Identification of HLA-DRB1-bound self-peptides following measles virus infection. J Immunol Methods. 2005;297:153-67 pubmed
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Pashine A, Busch R, Belmares M, Munning J, Doebele R, Buckingham M, et al. Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. Immunity. 2003;19:183-92 pubmed
| |
Gehring A, Rojas R, Canaday D, Lakey D, Harding C, Boom W. The Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits gamma interferon-regulated HLA-DR and Fc gamma R1 on human macrophages through Toll-like receptor 2. Infect Immun. 2003;71:4487-97 pubmed
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Hegde N, Tomazin R, Wisner T, Dunn C, Boname J, Lewinsohn D, et al. Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class II antigen presentation. J Virol. 2002;76:10929-41 pubmed
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Patil N, Pashine A, Belmares M, Liu W, Kaneshiro B, Rabinowitz J, et al. Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles. J Immunol. 2001;167:7157-68 pubmed
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Kostelny S, Link B, Tso J, Vasquez M, Jorgensen B, Wang H, et al. Humanization and characterization of the anti-HLA-DR antibody 1D10. Int J Cancer. 2001;93:556-65 pubmed
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Doebele R, Busch R, Scott H, Pashine A, Mellins E. Determination of the HLA-DM interaction site on HLA-DR molecules. Immunity. 2000;13:517-27 pubmed
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Bainbridge D, Ellis S, Sargent I. HLA-G suppresses proliferation of CD4(+) T-lymphocytes. J Reprod Immunol. 2000;48:17-26 pubmed
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van Ham M, van Lith M, Lillemeier B, Tjin E, Gruneberg U, Rahman D, et al. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J Exp Med. 2000;191:1127-36 pubmed
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Texier C, Pouvelle S, Busson M, Herve M, Charron D, Menez A, et al. HLA-DR restricted peptide candidates for bee venom immunotherapy. J Immunol. 2000;164:3177-84 pubmed
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Bertho N, Drenou B, Laupeze B, Berre C, Amiot L, Grosset J, et al. HLA-DR-mediated apoptosis susceptibility discriminates differentiation stages of dendritic/monocytic APC. J Immunol. 2000;164:2379-85 pubmed
| |
Appel H, Gauthier L, Pyrdol J, Wucherpfennig K. Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells. J Biol Chem. 2000;275:312-21 pubmed
| |
Hohn H, Pilch H, Günzel S, Neukirch C, Hilmes C, Kaufmann A, et al. CD4+ tumor-infiltrating lymphocytes in cervical cancer recognize HLA-DR-restricted peptides provided by human papillomavirus-E7. J Immunol. 1999;163:5715-22 pubmed
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product information
brand :
Novus
master code :
NB600-587
SKU :
NB600-587
product name :
TNF-alpha Antibody - Azide Free
description :
The TNF-alpha Antibody - Azide Free from Novus Biologicals is a rabbit polyclonal antibody to TNF-alpha. This antibody reacts with human, mouse, rat, chicken, primate. The TNF-alpha Antibody - Azide Free has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
target :
TNF-alpha
category :
Primary Antibodies
sizes available :
0.2 ml (also 0.04 ml)
buffer :
Antiserum
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The whole rabbit serum was prepared by repeated immunizations with recombinant human TNF-alpha produced in E.coli. (Uniprot: P01375)
isotype :
Serum
purity :
Delipidation and Defibrination
species :
Human, Mouse, Rat, Chicken, Primate
specificity :
The antiserum is directed against mature 17,000 MW human TNF-alpha and is useful in determining its presence in various assays
theoretical molecular weight :
25.64 kDa
gene symbol :
TNF
applications :
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
USD :
323
USD 2023 :
329 USD
alt names :
APC1 protein, Cachectin, DIF, TNF, monocyte-derived, TNF-a, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
storage :
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
more info or order :
company information

Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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