This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
pan Actin Antibody (ACTN05 (C4))
catalog :
NB600-535
quantity :
500 uL (also 100 ul)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ACTN05 (C4)
reactivity :
human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 31
Reference
Luedeman M, Stroik S, Feng W, Luthman A, Gupta G, Ramsden D. Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection. Nat Commun. 2022;13:4547 pubmed publisher
Bhattacharjee S, Rehman I, Basu S, Nandy S, Richardson J, Das B. Interplay between symmetric arginine dimethylation and ubiquitylation regulates TDP1 proteostasis for the repair of topoisomerase I-DNA adducts. Cell Rep. 2022;39:110940 pubmed publisher
Simoes S, Guo J, Buitrago L, Qureshi Y, Feng X, Kothiya M, et al. Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling. Cell Rep. 2021;37:110182 pubmed publisher
Simoes S, Neufeld J, Triana Baltzer G, Moughadam S, Chen E, Kothiya M, et al. Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans. Sci Transl Med. 2020;12: pubmed publisher
Pasula S, Tessneer K, Fu Y, Gopalakrishnan J, Pelikan R, Kelly J, et al. Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network. Arthritis Rheumatol. 2020;72:780-790 pubmed publisher
Le H, Sato F, Kohsaka A, Bhawal U, Nakao T, Muragaki Y, et al. Dec1 Deficiency Suppresses Cardiac Perivascular Fibrosis Induced by Transverse Aortic Constriction. Int J Mol Sci. 2019;20: pubmed publisher
Li C, Zhu B, Son Y, Wang Z, Jiang L, Xiang M, et al. The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality. Immunity. 2019;51:491-507.e7 pubmed publisher
Jarjour N, Schwarzkopf E, Bradstreet T, Shchukina I, Lin C, Huang S, et al. Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity. Nat Immunol. 2019;20:687-700 pubmed publisher
Sato F, Otsuka T, Kohsaka A, Le H, Bhawal U, Muragaki Y. Smad3 Suppresses Epithelial Cell Migration and Proliferation Via the Clock Gene Dec1, Which Negatively Regulates the Expression of Clock Genes Dec2 and Per1. Am J Pathol. 2019;: pubmed publisher
Maidorn M, Olichon A, Rizzoli S, Opazo F. Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons. MAbs. 2019;11:305-321 pubmed publisher
Richter K, Wildhagen H, Helm M, Ußling J, Schikorski T, Rizzoli S. Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins. Sci Rep. 2018;8:14838 pubmed publisher
Qureshi Y, Patel V, Berman D, Kothiya M, Neufeld J, Vardarajan B, et al. An Alzheimer's Disease-Linked Loss-of-Function CLN5 Variant Impairs Cathepsin D Maturation, Consistent with a Retromer Trafficking Defect. Mol Cell Biol. 2018;38: pubmed publisher
Huynh J, Lin C, Kimmey J, Jarjour N, Schwarzkopf E, Bradstreet T, et al. Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. J Exp Med. 2018;215:1823-1838 pubmed publisher
Hamilton K, Wang Y, Raefsky S, Berkowitz S, Spangler R, Suire C, et al. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PLoS ONE. 2018;13:e0196223 pubmed publisher
Nakamura H, Bono H, Hiyama K, Kawamoto T, Kato Y, Nakanishi T, et al. Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions. PLoS ONE. 2018;13:e0192136 pubmed publisher
Williamson R, Laulagnier K, Miranda A, Fernandez M, Wolfe M, Sadoul R, et al. Disruption of amyloid precursor protein ubiquitination selectively increases amyloid ? (A?) 40 levels via presenilin 2-mediated cleavage. J Biol Chem. 2017;292:19873-19889 pubmed publisher
Liu Q, Imaizumi T, Murakami K, Tanaka H, Wu Y, Yoshizawa T, et al. DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial cells. Biomed Res. 2017;38:249-255 pubmed publisher
Murakami K, Wu Y, Imaizumi T, Aoki Y, Liu Q, Yan X, et al. DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells. Biomed Res. 2017;38:221-227 pubmed publisher
Sato F, Kohsaka A, Takahashi K, Otao S, Kitada Y, Iwasaki Y, et al. Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-?. Histochem Cell Biol. 2017;148:617-624 pubmed publisher
Sato H, Wu Y, Kato Y, Liu Q, Hirai H, Yoshizawa T, et al. DEC2 expression antagonizes cisplatin‑induced apoptosis in human esophageal squamous cell carcinoma. Mol Med Rep. 2017;16:43-48 pubmed publisher
Xu F, Wang Y, Tao T, Song D, Liu X. Calreticulin attenuated microwave radiation-induced human microvascular endothelial cell injury through promoting actin acetylation and polymerization. Cell Stress Chaperones. 2017;22:87-97 pubmed publisher
Sato F, Muragaki Y, Kawamoto T, Fujimoto K, Kato Y, Zhang Y. Rhythmic expression of DEC2 protein in vitro and in vivo. Biomed Rep. 2016;4:704-710 pubmed
Safdar A, Khrapko K, Flynn J, Saleem A, De Lisio M, Johnston A, et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2016;6:7 pubmed publisher
Lin C, Bradstreet T, Schwarzkopf E, Jarjour N, Chou C, Archambault A, et al. IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation. J Exp Med. 2016;213:251-71 pubmed publisher
Simpson D, Lemonie N, Morgan D, Gaddameedhi S, Kaufmann W. Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity. Cancers (Basel). 2015;7:1072-90 pubmed publisher
Xie S, Naslavsky N, Caplan S. Diacylglycerol kinase α regulates tubular recycling endosome biogenesis and major histocompatibility complex class I recycling. J Biol Chem. 2014;289:31914-26 pubmed publisher
Wilhelm B, Mandad S, Truckenbrodt S, Kr hnert K, Sch fer C, Rammner B, et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science. 2014;344:1023-8 pubmed publisher
Simone L, Caplan S, Naslavsky N. Role of phosphatidylinositol 4,5-bisphosphate in regulating EHD2 plasma membrane localization. PLoS ONE. 2013;8:e74519 pubmed publisher
Pietri M, Dakowski C, Hannaoui S, Alleaume Butaux A, Hernandez Rapp J, Ragagnin A, et al. PDK1 decreases TACE-mediated ?-secretase activity and promotes disease progression in prion and Alzheimer's diseases. Nat Med. 2013;19:1124-31 pubmed publisher
Michalak Z, Lebrun A, Di Miceli M, Rousset M, Crespel A, Coubes P, et al. IgG leakage may contribute to neuronal dysfunction in drug-refractory epilepsies with blood-brain barrier disruption. J Neuropathol Exp Neurol. 2012;71:826-38 pubmed publisher
Hijikata T, Nakamura A, Isokawa K, Imamura M, Yuasa K, Ishikawa R, et al. Plectin 1 links intermediate filaments to costameric sarcolemma through beta-synemin, alpha-dystrobrevin and actin. J Cell Sci. 2008;121:2062-74 pubmed publisher
product information
brand :
Novus
master code :
NB600-535
SKU :
NB600-535
product name :
pan Actin Antibody (ACTN05 (C4))
description :
The pan Actin Antibody (ACTN05 (C4)) from Novus is a mouse monoclonal antibody to pan Actin. This antibody reacts with human, mouse, rat, porcine, bovine, canine, chicken, protozoa, rabbit. The pan Actin Antibody (ACTN05 (C4)) has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.
target :
pan Actin
category :
Primary Antibodies
unit sizes :
500 uL (also 100 ul)
buffer :
PBS (pH 7.4) and 0.2% BSA
clonality :
Monoclonal
clone :
ACTN05 (C4)
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Chicken gizzard actin
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Protozoa, Rabbit
specificity :
This antibody reacts with all six known vertebrate isoforms of actin (approximately 42kDa)
gene symbol :
ACTA1
images :
https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0022.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0022.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0022.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0021.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0021.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0021.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0017.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0017.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0017.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0008.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0008.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0008.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0010.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0010.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0010.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0020.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0020.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0020.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0019.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0019.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Western-Blot-NB600-535-img0019.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0011.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0011.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0011.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0012.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0012.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0012.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0013.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0013.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0013.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0014.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0014.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunocytochemistry-Immunofluorescence-NB600-535-img0014.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0015.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0015.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0015.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0016.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0016.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunohistochemistry-Paraffin-NB600-535-img0016.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunoprecipitation-NB600-535-img0018.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunoprecipitation-NB600-535-img0018.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/pan-Actin-Antibody-(ACTN05-(C4))-Immunoprecipitation-NB600-535-img0018.jpg
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin
USD :
429 USD
alt names :
ACTA, actin, alpha 1, skeletal muscle, alpha skeletal muscle, alpha skeletal muscle actin, alpha-actin-1, ASMA, CFTD, CFTDM, MPFD, NEM1, NEM2, NEM3
storage :
Store at 4C. Do not freeze.
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.