Siglec-1/CD169 Antibody (HSn 7D2) - BSA Free | Novus Biologicals NB600-534 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Siglec-1/CD169 Antibody (HSn 7D2) - BSA Free

catalog :

NB600-534

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HSn 7D2

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 21

Reference
Zwart E, van Ee T, Affandi A, Boyd L, Rodriguez E, den Haan J, et al. Spatial immune composition of tumor microenvironment in patients with pancreatic cancer. Cancer Immunol Immunother. 2023;72:4385-4397 pubmed publisher
Wang Y, Jin Z, Sun J, Chen X, Xie P, Zhou Y, et al. The role of activated monocyte IFN/SIGLEC1 signalling in Graves' disease. J Endocrinol. 2022;255:1-9 pubmed publisher
Singh D, Aladyeva E, Das S, Singh B, Esaulova E, Swain A, et al. Myeloid cell interferon responses correlate with clearance of SARS-CoV-2. Nat Commun. 2022;13:679 pubmed publisher
Tanboon J, Uruha A, Arahata Y, Dittmayer C, Schweizer L, Goebel H, et al. Inflammatory features in sporadic late-onset nemaline myopathy are independent from monoclonal gammopathy. Brain Pathol. 2021;31:e12962 pubmed publisher
Ostendorf L, Dittert P, Biesen R, Duchow A, Stiglbauer V, Ruprecht K, et al. SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients. Sci Rep. 2021;11:10299 pubmed publisher
Dupont M, Souriant S, Balboa L, Vu Manh T, Pingris K, Rousset S, et al. Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages. elife. 2020;9: pubmed publisher
Roos A, Preusse C, Hathazi D, Goebel H, Stenzel W. Proteomic Profiling Unravels a Key Role of Specific Macrophage Subtypes in Sporadic Inclusion Body Myositis. Front Immunol. 2019;10:1040 pubmed publisher
OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, et al. A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV. elife. 2018;7: pubmed publisher
Bihari C, Lal D, Thakur M, Sukriti S, Mathur D, Patil A, et al. Suboptimal Level of Bone-Forming Cells in Advanced Cirrhosis are Associated with Hepatic Osteodystrophy. Hepatol Commun. 2018;2:1095-1110 pubmed publisher
Jadapalli J, Wright G, Kain V, Sherwani M, Sonkar R, Yusuf N, et al. Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium. Am J Physiol Heart Circ Physiol. 2018;315:H1091-H1100 pubmed publisher
Akiyama H, Ramirez N, Gibson G, Kline C, Watkins S, Ambrose Z, et al. Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon. J Virol. 2017;91: pubmed publisher
de Carvalho L, Ngoumou G, Park J, Ehmke N, Deigendesch N, Kitabayashi N, et al. Musculoskeletal Disease in MDA5-Related Type I Interferonopathy: A Mendelian Mimic of Jaccoud's Arthropathy. Arthritis Rheumatol. 2017;69:2081-2091 pubmed publisher
Novakovic P, Harding J, Ladinig A, Al Dissi A, MacPhee D, Detmer S. Relationships of CD163 and CD169 positive cell numbers in the endometrium and fetal placenta with type 2 PRRSV RNA concentration in fetal thymus. Vet Res. 2016;47:76 pubmed publisher
Yayi H, Yeda X, Huaxin W, Yang W, Qian S, Zhongyuan X. Toll-like receptor 7 involves the injury in acute kidney ischemia/reperfusion of STZ-induced diabetic rats. Acta Cir Bras. 2016;31:448-55 pubmed publisher
Groenendyk J, Lee D, Jung J, Dyck J, Lopaschuk G, Agellon L, et al. Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis. PLoS ONE. 2016;11:e0159682 pubmed publisher
Kusumi S, Koga D, Kanda T, Ushiki T. Three-dimensional reconstruction of serial sections for analysis of the microvasculature of the white pulp and the marginal zone in the human spleen. Biomed Res. 2015;36:195-203 pubmed publisher
Akiyama H, Ramirez N, Gudheti M, Gummuluru S. CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies. PLoS Pathog. 2015;11:e1004751 pubmed publisher
Puryear W, Akiyama H, Geer S, Ramirez N, Yu X, Reinhard B, et al. Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169. PLoS Pathog. 2013;9:e1003291 pubmed publisher
Rempel H, Calosing C, Sun B, Pulliam L. Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity. PLoS ONE. 2008;3:e1967 pubmed publisher
Pack M, Trumpfheller C, Thomas D, Park C, Granelli Piperno A, MUNZ C, et al. DEC-205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp. Immunology. 2008;123:438-46 pubmed
Hartnell A, Steel J, Turley H, Jones M, Jackson D, Crocker P. Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations. Blood. 2001;97:288-96 pubmed

image

image 1 :

Immunohistochemistry-Frozen: Siglec-1/CD169 Antibody (HSn 7D2) [NB600-534] - Adult mouse small intestine. NB600-534 Siglec-1 was used at 1:500 and labeled with Alexa Fluor 568 conjugated secondary antibody (Red). DAPI shown as blue. Image from verified customer review.

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB600-534

SKU :

NB600-534

product name :

Siglec-1/CD169 Antibody (HSn 7D2) - BSA Free

description :

The Siglec-1/CD169 Antibody (HSn 7D2) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to Siglec-1/CD169. This antibody reacts with human,mouse,porcine,virus. The Siglec-1/CD169 Antibody (HSn 7D2) - BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Radioimmunoassay,In vivo assay,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vitro assay,Immunocytochemistry/ Immunofluorescence.

target :

Siglec-1/CD169

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

HSn 7D2

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full-length purified human Sialoadhesin (d1-4)Fc protein. [Swiss-Prot# Q9BZZ2]

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse,Porcine,Virus

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

gene symbol :

SIGLEC1

accessionNumbers :

Q9BZZ2

applications :

ELISA,Immunohistochemistry,Radioimmunoassay,In vivo assay,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vitro assay,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin

more info or order :

Novus Biologicals product webpage