Aflatoxin B1 Antibody (6A10) - BSA Free | Novus Biologicals NB600-443 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Aflatoxin B1 Antibody (6A10) - BSA Free

catalog :

NB600-443

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6A10

reactivity :

rat, pigs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot

more info or order :

Novus Biologicals product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; pigs ; 1:200; loading ...; fig 2d immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 5d	Zhang J, Hu S, Zhao C, Zhou Y, Zhang L, Liu H, et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants (Basel). 2022;11: pubmed publisher
	Huang L, Long Q, Su Q, Zhu X, Long X. Aflatoxin B1-DNA adducts modify the effects of post-operative adjuvant transarterial chemoembolization improving hepatocellular carcinoma prognosis. Explor Target Antitumor Ther. 2023;4:780-792 pubmed publisher
	Xu C, Cheng S, Chen K, Song Q, Liu C, Fan C, et al. Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity. Cell Mol Gastroenterol Hepatol. 2023;15:327-354 pubmed publisher
	Gramantieri L, Gnudi F, Vasuri F, Mandrioli D, Fornari F, Tovoli F, et al. Aflatoxin B1 DNA-Adducts in Hepatocellular Carcinoma from a Low Exposure Area. Nutrients. 2022;14: pubmed publisher
	Zhu Q, Ma Y, Liang J, Wei Z, Li M, Zhang Y, et al. AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma. Signal Transduct Target Ther. 2021;6:299 pubmed publisher
	Ates M, Ortatatli M. The effects of Nigella sativa seeds and thymoquinone on aflatoxin phase-2 detoxification through glutathione and glutathione-S-transferase alpha-3, and the relationship between aflatoxin B1-DNA adducts in broilers. Toxicon. 2021;193:86-92 pubmed publisher
	Wang L, He L, Zeng H, Fu W, Wang J, Tan Y, et al. Low-dose microcystin-LR antagonizes aflatoxin B1 induced hepatocarcinogenesis through decreasing cytochrome P450 1A2 expression and aflatoxin B1-DNA adduct generation. Chemosphere. 2020;248:126036 pubmed publisher
	Kim J, Park S, Do K, Kim D, Moon Y. Interference with mutagenic aflatoxin B1-induced checkpoints through antagonistic action of ochratoxin A in intestinal cancer cells: a molecular explanation on potential risk of crosstalk between carcinogens. Oncotarget. 2016;7:39627-39639 pubmed publisher
	Qureshi H, Hamid S, Ali S, Anwar J, Siddiqui A, Khan N. Cytotoxic effects of aflatoxin B1 on human brain microvascular endothelial cells of the blood-brain barrier. Med Mycol. 2015;53:409-16 pubmed publisher
	Liu Y, Long X, Xi Z, Ma Y, Huang X, Yao J, et al. MicroRNA-24 modulates aflatoxin B1-related hepatocellular carcinoma prognosis and tumorigenesis. Biomed Res Int. 2014;2014:482926 pubmed publisher
	Qi L, Bai T, Chen Z, Wu F, Chen Y, De Xiang B, et al. The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure. Liver Int. 2015;35:999-1009 pubmed publisher
	Qi L, Li L, Chen Y, Chen Z, Bai T, Xiang B, et al. Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China. PLoS ONE. 2013;8:e83465 pubmed publisher
	Huang X, Yao J, Huang H, Wang C, Ma Y, Xia Q, et al. MicroRNA-429 Modulates Hepatocellular Carcinoma Prognosis and Tumorigenesis. Gastroenterol Res Pract. 2013;2013:804128 pubmed publisher
	Zhang Z, Lu H, Huan F, Meghan C, Yang X, Wang Y, et al. Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. Int J Cancer. 2014;134:1539-48 pubmed publisher
	Yang X, Zhang Z, Wang X, Wang Y, Zhang X, Lu H, et al. Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage. Toxicol Appl Pharmacol. 2013;270:114-21 pubmed publisher
	Lu J, Yang W, Lin Y, Jin S, Yuh C. Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta Histochem. 2013;115:728-39 pubmed publisher
	Yang X, Lu H, Li Z, Bian Q, Qiu L, Li Z, et al. Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and apoptosis in human bronchial epithelial cells. Toxicology. 2012;300:138-48 pubmed publisher
	Shirabe K, Toshima T, Taketomi A, Taguchi K, Yoshizumi T, Uchiyama H, et al. Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan. Liver Int. 2011;31:1366-72 pubmed publisher
	Long X, Ma Y, Zhou Y, Yao J, Ban F, Huang Y, et al. XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk. BMC Cancer. 2009;9:400 pubmed publisher
	Besaratinia A, Kim S, Hainaut P, Pfeifer G. In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure. Gastroenterology. 2009;137:1127-37, 1137.e1-5 pubmed publisher
	Ochsner U, Bell S, O Leary A, Hoang T, Stone K, Young C, et al. Inhibitory effect of REP3123 on toxin and spore formation in Clostridium difficile, and in vivo efficacy in a hamster gastrointestinal infection model. J Antimicrob Chemother. 2009;63:964-71 pubmed publisher
	Lunn R, Langlois R, Hsieh L, Thompson C, Bell D. XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res. 1999;59:2557-61 pubmed

image

image 1 :

Immunohistochemistry: Aflatoxin B1 Antibody (6A10) [NB600-443] - Staining of positive (A) and negative (B) tumor tissues for AFB, -DNA adducts. Photos courtesy of Dr. Regina Santella.

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB600-443

SKU :

NB600-443

product name :

Aflatoxin B1 Antibody (6A10) - BSA Free

description :

The Aflatoxin B1 Antibody (6A10) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to Aflatoxin B1. This antibody reacts with all species,human,mouse,rat,fish - danio rerio (zebrafish). The Aflatoxin B1 Antibody (6A10) - BSA Free has been validated for the following applications: Dot Blot,CoIP,Cytometric Bead Assay Standard,IF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.

target :

Aflatoxin B1

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

6A10

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Aflatoxin B1 DNA (against the midazole ring-opened persistent form of the major N-7 guanine adduct of AFB1).

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

All Species,Human,Mouse,Rat,Zebrafish

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

applications :

Dot Blot,CoIP,Cytometric Bead Assay Standard,IF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

AFB1, AFB1-AR1, Aldoketoreductase 7

more info or order :

Novus Biologicals product webpage