product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
c-Myc Antibody
catalog :
NB600-336
quantity :
0.1 ml (also 0.025 ml)
price :
379 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Yang L, Liu Y, Wang M, Qian Y, Dong X, Gu H, et al. Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis. Mol Med Rep. 2016;14:4559-4566 pubmed publisher
Zeb A, Choubey V, Gupta R, Kuum M, Safiulina D, Vaarmann A, et al. A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy. Redox Biol. 2021;48:102186 pubmed publisher
Settelmeier S, Schreiber T, M ki J, Byts N, Koivunen P, Myllyharju J, et al. Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice. PLoS ONE. 2020;15:e0233261 pubmed publisher
Akella N, Le Minh G, Ciraku L, Mukherjee A, Bacigalupa Z, Mukhopadhyay D, et al. O-GlcNAc Transferase Regulates Cancer Stem-like Potential of Breast Cancer Cells. Mol Cancer Res. 2020;18:585-598 pubmed publisher
Babosova O, Kapralova K, Raskova Kafkova L, Korinek V, Divoky V, Prchal J, et al. Iron chelation and 2-oxoglutarate-dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1. J Cell Mol Med. 2019;23:7785-7795 pubmed publisher
Valzania L, Mattee M, Strand M, Brown M. Blood feeding activates the vitellogenic stage of oogenesis in the mosquito Aedes aegypti through inhibition of glycogen synthase kinase 3 by the insulin and TOR pathways. Dev Biol. 2019;: pubmed publisher
Dabral S, Muecke C, Valasarajan C, Schmoranzer M, Wietelmann A, Semenza G, et al. A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension. Nat Commun. 2019;10:2130 pubmed publisher
Kurelac I, Iommarini L, Vatrinet R, Amato L, De Luise M, Leone G, et al. Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. Nat Commun. 2019;10:903 pubmed publisher
Liu S, Zhang G, Guo J, Chen X, Lei J, Ze K, et al. Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. Nat Commun. 2018;9:5426 pubmed publisher
Deygas M, Gadet R, Gillet G, Rimokh R, Gonzalo P, Mikaelian I. Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen. Nat Commun. 2018;9:4545 pubmed publisher
Kim G, Das R, Rao X, Zhong J, Deiuliis J, Ramirez Bergeron D, et al. CITED2 Restrains Proinflammatory Macrophage Activation and Response. Mol Cell Biol. 2018;38: pubmed publisher
Hu J, Wang W, Zhang F, Li P, Boini K, Yi F, et al. Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells. Sci Rep. 2017;7:15878 pubmed publisher
Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed publisher
Wottawa M, Naas S, Bottger J, van Belle G, Mobius W, Revelo N, et al. Hypoxia-stimulated membrane trafficking requires T-plastin. Acta Physiol (Oxf). 2017;221:59-73 pubmed publisher
Burr S, Costa A, Grice G, Timms R, Lobb I, Freisinger P, et al. Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1? Stability in Aerobic Conditions. Cell Metab. 2016;24:740-752 pubmed publisher
Lam Y, Lecce L, Tan J, Bursill C, Handelsman D, Ng M. Androgen Receptor-Mediated Genomic Androgen Action Augments Ischemia-Induced Neovascularization. Endocrinology. 2016;157:4853-4864 pubmed
Tao Y, Lin F, Li R, Shen J, Wang Z. Prolyl hydroxylase-2 inhibits liver tumor cell proliferation and cyclin D1 expression in a hydroxylase-dependent manner. Int J Biochem Cell Biol. 2016;77:129-140 pubmed publisher
Mysore V, Szablowski J, Dervan P, FROST P. A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity. Mol Cancer Res. 2016;14:253-66 pubmed publisher
Sun W, Kosyna F, Jelkmann W, Depping R. Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis by Maintaining Hepatocyte Nuclear Factor-4α Expression. Cell Physiol Biochem. 2015;37:2257-64 pubmed publisher
Högel H, Miikkulainen P, Bino L, Jaakkola P. Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27. Mol Cancer. 2015;14:143 pubmed publisher
Ryou M, Choudhury G, Li W, Winters A, Yuan F, Liu R, et al. Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress. Neuroscience. 2015;301:193-203 pubmed publisher
Zhang Z, Pang X, Tang Z, Yin D, Wang Z. Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells. Mol Med Rep. 2015;12:3809-3814 pubmed publisher
Kumar P, Gullberg U, Olsson I, Ajore R. Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS ONE. 2015;10:e0123725 pubmed publisher
Clairfeuille T, Norwood S, Qi X, Teasdale R, Collins B. Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21. J Biol Chem. 2015;290:14504-17 pubmed publisher
Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed publisher
Li J, Yuan W, Jiang S, Ye W, Yang H, Shapiro I, et al. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus. J Biol Chem. 2015;290:7195-207 pubmed publisher
Vogler M, Zieseniss A, Hesse A, Levent E, Tiburcy M, Heinze E, et al. Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult. Pflugers Arch. 2015;467:2141-9 pubmed publisher
product information
brand :
Novus
master code :
NB600-336
SKU :
NB600-336
product name :
c-Myc Antibody
description :
The c-Myc Antibody from Novus Biologicals is a rabbit polyclonal antibody to c-Myc. This antibody reacts with human, mouse, insect, s. pombe. The c-Myc Antibody has been validated for the following applications: Western Blot, Simple Western, Chromatin Immunoprecipitation, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.
target :
c-Myc
category :
Primary Antibodies
sizes available :
0.1 ml (also 0.025 ml)
buffer :
Tris-Glycine, 0.15 M NaCl
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to the human c-Myc Antibody (between residues 385-435) [Uniprot: P01106]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Insect, S. pombe
theoretical molecular weight :
48.8 kDa
gene symbol :
MYC
accessionNumbers :
P01106
applications :
Western Blot, Simple Western, Chromatin Immunoprecipitation, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin
USD :
356
USD 2023 :
379 USD
alt names :
avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.