c-Myc Antibody (9E10) - BSA Free | Novus Biologicals NB600-302 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

c-Myc Antibody (9E10) - BSA Free

catalog :

NB600-302

quantity :

0.1 ml (also 0.025 ml)

price :

379 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9.00E+10

reactivity :

human, mouse, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 38

Published Application/Species/Sample/Dilution	Reference
western blot; human	Iampietro M, Morissette G, Gravel A, Flamand L. Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein. J Virol. 2014;88:12452-63 pubmed publisher
immunoprecipitation; mouse	Santini E, Feyder M, Gangarossa G, Bateup H, Greengard P, Fisone G. Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism. J Biol Chem. 2012;287:27806-12 pubmed publisher
immunoprecipitation; human western blot; human	Wang H, Shao Z, Shi L, Hwang P, Truong L, Berns M, et al. CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks. J Biol Chem. 2012;287:21471-80 pubmed publisher
western blot; human	Zhao Y, Wang Y, Hu J, Zhang X, Zhang Y. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates ?-cleavage of ?-amyloid precursor protein (APP) through interacting with ?-site APP cleaving protein 1 (BACE1). J Biol Chem. 2012;287:11141-50 pubmed publisher
immunoprecipitation; human western blot; human	Hubbi M, Luo W, Baek J, Semenza G. MCM proteins are negative regulators of hypoxia-inducible factor 1. Mol Cell. 2011;42:700-12 pubmed publisher
immunoprecipitation; human immunocytochemistry; human western blot; human	Trinkle Mulcahy L, Chusainow J, Lam Y, Swift S, Lamond A. Visualization of intracellular PP1 targeting through transiently and stably expressed fluorescent protein fusions. Methods Mol Biol. 2007;365:133-54 pubmed
western blot; mouse	Bergman M, Teerlink J, Mahimkar R, Li L, Zhu B, Nguyen A, et al. Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am J Physiol Heart Circ Physiol. 2007;292:H1847-60 pubmed
immunoprecipitation; human	Kari B, Lussenhop N, Goertz R, Wabuke Bunoti M, Radeke R, Gehrz R. Characterization of monoclonal antibodies reactive to several biochemically distinct human cytomegalovirus glycoprotein complexes. J Virol. 1986;60:345-52 pubmed
	Harbauer A, Hees J, Wanderoy S, Segura I, Gibbs W, Cheng Y, et al. Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy. Neuron. 2022;110:1516-1531.e9 pubmed publisher
	Shen M, Wei Y, Kim H, Wan L, Jiang Y, Hang X, et al. Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer. 2022;3:43-59 pubmed publisher
	Kumagai S, Koyama S, Itahashi K, Tanegashima T, Lin Y, Togashi Y, et al. Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments. Cancer Cell. 2022;40:201-218.e9 pubmed publisher
	Basu H, Pekkurnaz G, Falk J, Wei W, Chin M, Steen J, et al. FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply. J Cell Biol. 2021;220: pubmed publisher
	Li K, Wang F, Yang Z, Zhang T, Yuan Y, Zhao C, et al. TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradation. Nat Commun. 2020;11:6316 pubmed publisher
	Bewley M, Gautam L, Jagadeeshaprasad M, Gowda D, Flanagan J. Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding. J Biol Chem. 2020;295:18589-18603 pubmed publisher
	Zhao L, Han X, Lu J, McEachern D, Wang S. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. Neoplasia. 2020;22:522-532 pubmed publisher
	Schüchner S, Behm C, Mudrak I, Ogris E. The Myc tag monoclonal antibody 9E10 displays highly variable epitope recognition dependent on neighboring sequence context. Sci Signal. 2020;13: pubmed publisher
	Pedrosa A, Bodrug N, Gómez Escudero J, Carter E, Reynolds L, Georgiou P, et al. Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861. Cancer Res. 2019;: pubmed publisher
	Ida K, Miyamoto T, Higuchi S, Takeuchi H, Yamada S, Ono M, et al. Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study. Med Oncol. 2019;36:62 pubmed publisher
	Morioka S, Perry J, Raymond M, Medina C, Zhu Y, Zhao L, et al. Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. Nature. 2018;563:714-718 pubmed publisher
	Wu J, Fan W, Ma L, Geng X. miR-708-5p promotes fibroblast-like synoviocytes' cell apoptosis and ameliorates rheumatoid arthritis by the inhibition of Wnt3a/β-catenin pathway. Drug Des Devel Ther. 2018;12:3439-3447 pubmed publisher
	Rodríguez Muela N, Parkhitko A, Grass T, Gibbs R, Norabuena E, Perrimon N, et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. J Clin Invest. 2018;128:3008-3023 pubmed publisher
	Mahadevan S, Sathappan V, Utama B, Lorenzo I, Kaskar K, Van den Veyver I. Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming. Sci Rep. 2017;7:44667 pubmed publisher
	van der Kant R, Jonker C, Wijdeven R, Bakker J, Janssen L, Klumperman J, et al. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. J Biol Chem. 2015;290:30280-90 pubmed publisher
	da Costa J, Carvalhais V, Amado F, Silva A, Nogueira Ferreira R, Ferreira R, et al. Anti-tumoral activity of human salivary peptides. Peptides. 2015;71:170-8 pubmed publisher
	Jang K, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, et al. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Nat Commun. 2015;6:6750 pubmed publisher
	Pekkurnaz G, Trinidad J, Wang X, Kong D, Schwarz T. Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase. Cell. 2014;158:54-68 pubmed publisher
	Barnett T, Liebl D, Seymour L, Gillen C, Lim J, LaRock C, et al. The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication. Cell Host Microbe. 2013;14:675-82 pubmed publisher
	Hsieh Y, Chou M, Chen H, Tseng J. IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1. Gynecol Oncol. 2013;131:182-90 pubmed publisher
	Hubbi M, Hu H, Kshitiz -, Gilkes D, Semenza G. Sirtuin-7 inhibits the activity of hypoxia-inducible factors. J Biol Chem. 2013;288:20768-75 pubmed publisher
	Megill A, Lee T, Dibattista A, Song J, Spitzer M, Rubinshtein M, et al. A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. J Neurosci. 2013;33:9306-18 pubmed publisher
	Wang H, Shi L, Wong C, Han X, Hwang P, Truong L, et al. The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair. PLoS Genet. 2013;9:e1003277 pubmed publisher
	Lu C, Truong L, Aslanian A, Shi L, Li Y, Hwang P, et al. The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination. J Biol Chem. 2012;287:43984-94 pubmed publisher
	Al Sorkhy M, Ferraiuolo R, Jalili E, Malysa A, Fratiloiu A, Sloane B, et al. The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer. BMC Cancer. 2012;12:45 pubmed publisher
	Kim M, Jung J, Mo J, Ann E, Ahn J, Yoon J, et al. The intracellular domain of Jagged-1 interacts with Notch1 intracellular domain and promotes its degradation through Fbw7 E3 ligase. Exp Cell Res. 2011;317:2438-46 pubmed publisher
	Murri Plesko M, Hulikova A, Oosterwijk E, Scott A, Zortea A, Harris A, et al. Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX. Eur J Pharmacol. 2011;657:173-83 pubmed publisher
	Silvestri L, Pagani A, Camaschella C. Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Blood. 2008;111:924-31 pubmed
	Hilpert K, Hansen G, Wessner H, Kuttner G, Welfle K, Seifert M, et al. Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. Protein Eng. 2001;14:803-6 pubmed
	Bello Fernandez C, Packham G, Cleveland J. The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc Natl Acad Sci U S A. 1993;90:7804-8 pubmed

product information

brand :

Novus

master code :

NB600-302

SKU :

NB600-302

product name :

c-Myc Antibody (9E10) - BSA Free

description :

The c-Myc Antibody (9E10) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to c-Myc. This antibody reacts with human, mouse, bovine, drosophila. The c-Myc Antibody (9E10) - BSA Free has been validated for the following applications: Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Proximity Ligation Assay, Sandwich ELISA, Flow (Intracellular).

target :

c-Myc

category :

Primary Antibodies

sizes available :

0.1 ml (also 0.025 ml)

buffer :

PBS

clonality :

Monoclonal

clone :

9.00E+10

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

A synthetic peptide corresponding to amino acids 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) of human c-Myc Antibody (9E10). [UniProt# P01106]

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human, Mouse, Bovine, Drosophila

specificity :

Specific for the c-myc protein in random coil configuration, not as a helix

theoretical molecular weight :

48.8 kDa

gene symbol :

MYC

accessionNumbers :

P01106

applications :

Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Proximity Ligation Assay, Sandwich ELISA, Flow (Intracellular)

USD :

356

USD 2023 :

379 USD

alt names :

9E10 anti-Myc, 9E10 Myc, avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage