KMT2A/MLL Antibody | Novus Biologicals NB600-248 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

KMT2A/MLL Antibody

catalog :

NB600-248

quantity :

100 ul

price :

499 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 17

Reference
Zhu G, Luo H, Feng Y, Guryanova O, Xu J, Chen S, et al. HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia. Nat Commun. 2021;12:1956 pubmed publisher
Toyohara T, Roudnicky F, Florido M, Nakano T, Yu H, Katsuki S, et al. Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis. Cell Stem Cell. 2020;27:147-157.e7 pubmed publisher
Kim H, Seo J, Lee S, Ha K, Choi B, Shin Y, et al. AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice. Brain Behav Immun. 2020;87:765-776 pubmed publisher
Liang F, Huang T, Li B, Zhao Y, Zhang X, Xu B. High-intensity interval training and moderate-intensity continuous training alleviate β-amyloid deposition by inhibiting NLRP3 inflammasome activation in APPswe/PS1dE9 mice. Neuroreport. 2020;31:425-432 pubmed publisher
Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, et al. HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Cancer Cell. 2019;36:645-659.e8 pubmed publisher
Verma V, Gupta S, Kumar P, Yadav S, Dhanda R, Gaind R, et al. Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections. Front Microbiol. 2019;10:2020 pubmed publisher
Liu J, Yang C, Zhang W, Su H, Liu Z, Pan Q, et al. Disturbance of mitochondrial dynamics and mitophagy in sepsis-induced acute kidney injury. Life Sci. 2019;235:116828 pubmed publisher
Geyfman M, Debabov D, Poloso N, Alvandi N. Mechanistic insight into the activity of a sulfone compound dapsone on Propionibacterium (Newly Reclassified as Cutibacterium) Acnes-mediated cytokine production. Exp Dermatol. 2019;28:190-197 pubmed publisher
Pan Z, Shan Q, Gu P, Wang X, Tai L, Sun M, et al. miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis. J Neuroinflammation. 2018;15:29 pubmed publisher
Zhuang J, Wen X, Zhang Y, Shan Q, Zhang Z, Zheng G, et al. TDP-43 upregulation mediated by the NLRP3 inflammasome induces cognitive impairment in 2 2',4,4'-tetrabromodiphenyl ether (BDE-47)-treated mice. Brain Behav Immun. 2017;65:99-110 pubmed publisher
Lee H, Lee S, Kim N, Park K, Choi B, Shin Y, et al. Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke. J Biophotonics. 2017;10:1502-1513 pubmed publisher
Macpherson M, Westbom C, Kogan H, Shukla A. Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro. Histochem Cell Biol. 2017;147:595-604 pubmed publisher
Zhu W, Cao F, Feng J, Chen H, Wan J, Lu Q, et al. NLRP3 inflammasome activation contributes to long-term behavioral alterations in mice injected with lipopolysaccharide. Neuroscience. 2017;343:77-84 pubmed publisher
Lu C, Xu W, Shao J, Zhang F, Chen A, Zheng S. Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes. Toxicol Sci. 2017;155:432-443 pubmed publisher
Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed publisher
Westbom C, Thompson J, Leggett A, Macpherson M, Beuschel S, Pass H, et al. Inflammasome Modulation by Chemotherapeutics in Malignant Mesothelioma. PLoS ONE. 2015;10:e0145404 pubmed publisher
Chi W, Chen H, Li F, Zhu Y, Yin W, Zhuo Y. HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-ÎºB pathway in acute glaucoma. J Neuroinflammation. 2015;12:137 pubmed publisher

product information

brand :

Novus

master code :

NB600-248

SKU :

NB600-248

product name :

KMT2A/MLL Antibody

description :

The KMT2A/MLL Antibody from Novus Biologicals is a rabbit polyclonal antibody to KMT2A/MLL. This antibody reacts with human, mouse. The KMT2A/MLL Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin.

target :

KMT2A/MLL

category :

Primary Antibodies

sizes available :

100 ul

buffer :

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residues 720 and 780 of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human, Mouse

gene symbol :

KMT2A

accessionNumbers :

Q03164

applications :

Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin

USD :

485

USD 2023 :

499 USD

alt names :

ALL1, ALL-1MLL/GAS7, CXXC7TET1-MLL, CXXC-type zinc finger protein 7, EC 2.1.1.43, HRXFLJ11783, HTRX, HTRX1MLL-AF4 der(11) fusion protein, KMT2ACDK6/MLL fusion protein, Lysine N-methyltransferase 2A, MLL/GAS7 fusion protein, MLL/GMPS fusion protein, MLL1, MLL1A, myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog), myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), Trithorax-like protein, TRX1histone-lysine N-methyltransferase MLL, Zinc finger protein HRX

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage