CD3 Antibody (SP7) | Novus Biologicals NB600-1441 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD3 Antibody (SP7)

catalog :

NB600-1441

quantity :

0.5 ml (also 0.1 ml)

price :

669 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP7

reactivity :

human, mouse, dogs

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 35

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100; loading ...; fig 4d	Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 6c immunohistochemistry - paraffin section; human; loading ...; fig s5	Fletcher R, Tong J, Risnik D, Leibowitz B, Wang Y, Concha Benavente F, et al. Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis. Oncogene. 2021;40:2035-2050 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; fig 1e	Dulken B, Buckley M, Navarro Negredo P, Saligrama N, Cayrol R, Leeman D, et al. Single-cell analysis reveals T cell infiltration in old neurogenic niches. Nature. 2019;571:205-210 pubmed publisher
	Fukushima H, Furusawa A, Kato T, Wakiyama H, Takao S, Okuyama S, et al. Intratumoral IL15 Improves Efficacy of Near-Infrared Photoimmunotherapy. Mol Cancer Ther. 2023;22:1215-1227 pubmed publisher
	Delcroix V, Mauduit O, Lee H, Ivanova A, Umazume T, Knox S, et al. The First Transcriptomic Atlas of the Adult Lacrimal Gland Reveals Epithelial Complexity and Identifies Novel Progenitor Cells in Mice. Cells. 2023;12: pubmed publisher
	Marvin D, Dijkstra J, Zulfiqar R, Vermeulen M, Ten Dijke P, Ritsma L. TGF-β Type I Receptor Signaling in Melanoma Liver Metastases Increases Metastatic Outgrowth. Int J Mol Sci. 2023;24: pubmed publisher
	Medina Rodríguez E, Han D, Lowell J, Beurel E. Stress promotes the infiltration of peripheral immune cells to the brain. Brain Behav Immun. 2023;111:412-423 pubmed publisher
	Huang S, Pan C, Lin Y, Chen M, Chen Y, Jan C, et al. BiTE-Secreting CAR-γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors. Adv Sci (Weinh). 2023;10:e2206856 pubmed publisher
	Prince L, Mart xed n Faivre L, Villeret B, Sanchez Guzman D, Le Guen P, Sallenave J, et al. Eosinophils Recruited during Pulmonary Vaccination Regulate Mucosal Antibody Production. Am J Respir Cell Mol Biol. 2023;68:186-200 pubmed publisher
	Piras R, Ko E, Barrett C, De Simone M, Lin X, Broz M, et al. circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment. Nat Commun. 2022;13:7243 pubmed publisher
	Pilling D, Sahlberg K, Karhadkar T, Chen W, Gomer R. The sialidase NEU3 promotes pulmonary fibrosis in mice. Respir Res. 2022;23:215 pubmed publisher
	Aung T, Shafi S, Wilmott J, Nourmohammadi S, Vathiotis I, Gavrielatou N, et al. Objective assessment of tumor infiltrating lymphocytes as a prognostic marker in melanoma using machine learning algorithms. EBioMedicine. 2022;82:104143 pubmed publisher
	Zhang X, Jiang S, Zhou X, Yu Z, Han S, Nan F, et al. Human Cytomegalovirus-IE2 Affects Embryonic Liver Development and Survival in Transgenic Mouse. Cell Mol Gastroenterol Hepatol. 2022;14:494-511 pubmed publisher
	Glennon E, Tongogara T, Primavera V, Reeder S, Wei L, Kaushansky A. Elucidating Spatially-Resolved Changes in Host Signaling During Plasmodium Liver-Stage Infection. Front Cell Infect Microbiol. 2021;11:804186 pubmed publisher
	Lu B, Gupta R, Aguirre Ducler A, Gianino N, Wyatt H, Ribeiro M, et al. Spatially resolved analysis of the T cell immune contexture in lung cancer-associated brain metastases. J Immunother Cancer. 2021;9: pubmed publisher
	Miao T, Wang T, Feng T, Yuan D, Guo Q, Xiong F, et al. Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology. Immunology. 2021;164:792-802 pubmed publisher
	Ji Y, Fan X, Zhang Y, Li J, Dai Z, Wu Z. Glycine regulates mucosal immunity and the intestinal microbial composition in weaned piglets. Amino Acids. 2021;: pubmed publisher
	Maisonneuve C, Tsang D, Foerster E, Robert L, Mukherjee T, Prescott D, et al. Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells. Cell Rep. 2021;34:108677 pubmed publisher
	Martinez Morilla S, Zugazagoitia J, Wong P, Kluger H, Rimm D. Quantitative analysis of CMTM6 expression in tumor microenvironment in metastatic melanoma and association with outcome on immunotherapy. Oncoimmunology. 2020;10:1864909 pubmed publisher
	Weiss S, Zito C, Tran T, Heishima K, Neumeister V, McGuire J, et al. Melanoma brain metastases have lower T-cell content and microvessel density compared to matched extracranial metastases. J Neurooncol. 2020;: pubmed publisher
	Fujimoto N, He Y, D Addio M, Tacconi C, Detmar M, Dieterich L. Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes. PLoS Biol. 2020;18:e3000704 pubmed publisher
	Lee H, Lee Y, Harenda Q, Pietrzak S, Oktay H, Schreiber S, et al. Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes. Cell Metab. 2020;31:822-836.e5 pubmed publisher
	Scortegagna M, Hockemeyer K, Dolgalev I, Poźniak J, Rambow F, Li Y, et al. Siah2 control of T-regulatory cells limits anti-tumor immunity. Nat Commun. 2020;11:99 pubmed publisher
	Manogaran P, Samardzija M, Schad A, Wicki C, Walker Egger C, Rudin M, et al. Retinal pathology in experimental optic neuritis is characterized by retrograde degeneration and gliosis. Acta Neuropathol Commun. 2019;7:116 pubmed publisher
	Toki M, Merritt C, Wong P, Smithy J, Kluger H, Syrigos K, et al. High-plex predictive marker discovery for melanoma immunotherapy treated patients using Digital Spatial Profiling. Clin Cancer Res. 2019;: pubmed publisher
	Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed publisher
	Du H, Hirabayashi K, Ahn S, Kren N, Montgomery S, Wang X, et al. Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells. Cancer Cell. 2019;35:221-237.e8 pubmed publisher
	Hartwig T, Zwicky P, Schreiner B, Yawalkar N, Cheng P, Navarini A, et al. Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation. Cell Rep. 2018;25:3564-3572.e4 pubmed publisher
	Toki M, Mani N, Smithy J, Liu Y, Altan M, Wasserman B, et al. Immune Marker Profiling and Programmed Death Ligand 1 Expression Across NSCLC Mutations. J Thorac Oncol. 2018;13:1884-1896 pubmed publisher
	Gushchina S, Pryce G, Yip P, Wu D, Pallier P, Giovannoni G, et al. Increased expression of colony-stimulating factor-1 in mouse spinal cord with experimental autoimmune encephalomyelitis correlates with microglial activation and neuronal loss. Glia. 2018;66:2108-2125 pubmed publisher
	Teillaud J, Regard L, Martin C, Siberil S, Burgel P. Exploring the Role of Tertiary Lymphoid Structures Using a Mouse Model of Bacteria-Infected Lungs. Methods Mol Biol. 2018;1845:223-239 pubmed publisher
	Gettinger S, Choi J, Mani N, Sanmamed M, Datar I, Sowell R, et al. A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers. Nat Commun. 2018;9:3196 pubmed publisher
	Carvajal Hausdorf D, Mani N, Velcheti V, Schalper K, Rimm D. Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer. J Immunother Cancer. 2017;5:81 pubmed publisher
	England C, Jiang D, Ehlerding E, Rekoske B, Ellison P, Hernandez R, et al. 89Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer. Eur J Nucl Med Mol Imaging. 2018;45:110-120 pubmed publisher
	Brown J, Wimberly H, Lannin D, Nixon C, Rimm D, Bossuyt V. Multiplexed quantitative analysis of CD3, CD8, and CD20 predicts response to neoadjuvant chemotherapy in breast cancer. Clin Cancer Res. 2014;20:5995-6005 pubmed publisher

product information

brand :

Novus

MasterCode :

NB600-1441

SKU :

NB600-1441

product name :

CD3 Antibody (SP7)

Description :

The CD3 Antibody (SP7) from NB600-1441 is a nb600-1441 antibody to . This antibody reacts with adaptive immunity, apoptosis, autoimmune diseases, diabetes research, immunology, inflammation, innate immunity, signal transduction, stem cells.

target :

CD3

category :

Primary Antibodies

unit size :

0.5 ml (also 0.1 ml)

buffer :

Tissue culture supernatant

clonality :

Monoclonal

clone :

SP7

conjugate :

Unconjugated

host :

Rabbit

immunogen :

This CD3 antibody was developed against a synthetic peptide: KAKAKPVTRGAGA, corresponding to amino acids 156-168 of Human CD3 epsilon chain.

isotype :

IgG

purity :

Tissue culture supernatant

species :

Human, Mouse, Porcine, Canine

specificity :

The CD3 antigen is present on early thymocytes and mature T cells and is generally regarded as a pan-T cell marker

theoretical molecular weight :

23.1 kDa

gene symbol :

CD3E

images :

https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD3-Antibody-(SP7)-Immunohistochemistry-Paraffin-NB600-1441-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD3-Antibody-(SP7)-Immunohistochemistry-Paraffin-NB600-1441-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD3-Antibody-(SP7)-Immunohistochemistry-Frozen-NB600-1441-img0002.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD3-Antibody-(SP7)-Immunohistochemistry-Frozen-NB600-1441-img0002.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD3-Antibody-(SP7)-Immunohistochemistry-Paraffin-NB600-1441-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD3-Antibody-(SP7)-Immunohistochemistry-Paraffin-NB600-1441-img0003.jpg

applications :

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

USD :

669 USD

alt names :

CD_antigen: CD3e, CD3 antigen, delta subunit, CD3d antigen, CD3d antigen, delta polypeptide (TiT3 complex), CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, CD3G, CD3g antigen, CD3g antigen, gamma polypeptide (TiT3 complex), CD3g molecule, epsilon (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, FLJ17620, FLJ17664, FLJ18683, FLJ79544, FLJ94613, IMD18, MGC138597, T3DOKT3, delta chain, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell receptor T3 delta chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage