GADD153/CHOP Antibody (9C8) | Novus Biologicals NB600-1335 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

GADD153/CHOP Antibody (9C8)

catalog :

NB600-1335

quantity :

0.1 ml (also 0.025 ml)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

9C8

reactivity :

primate, human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 41

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; loading ...; fig 4j	Herranen A, Ikäheimo K, Lankinen T, Pakarinen E, Fritzsch B, Saarma M, et al. Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss. Cell Death Dis. 2020;11:100 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5c	Pommier A, Anaparthy N, Memos N, Kelley Z, Gouronnec A, Yan R, et al. Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science. 2018;360: pubmed publisher
western blot; mouse; fig 1F	Zismanov V, Chichkov V, Colangelo V, Jamet S, Wang S, Syme A, et al. Phosphorylation of eIF2Î± Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell. 2016;18:79-90 pubmed publisher
immunohistochemistry - paraffin section; human	Lee Y, Hah Y, Ha Y, Kang Y, Kang K, Hwang J, et al. The autophagy-related marker LC3 can predict prognosis in human hepatocellular carcinoma. PLoS ONE. 2013;8:e81540 pubmed publisher
western blot; human	Lin C, Lee C, Shih Y, Lin C, Wang S, Chen T, et al. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells. PLoS ONE. 2012;7:e38706 pubmed publisher
immunocytochemistry; primate immunocytochemistry; human	Wang X, Harding H, Zhang Y, Jolicoeur E, Kuroda M, Ron D. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 1998;17:5708-17 pubmed
immunoprecipitation; mouse western blot; mouse	Wang X, Kuroda M, Sok J, Batchvarova N, Kimmel R, Chung P, et al. Identification of novel stress-induced genes downstream of chop. EMBO J. 1998;17:3619-30 pubmed
immunoprecipitation; human immunocytochemistry; human	Zinszner H, Sok J, Immanuel D, Yin Y, Ron D. TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. J Cell Sci. 1997;110 ( Pt 15):1741-50 pubmed
immunoprecipitation; mouse western blot; mouse	Saisanit S, Sun X. Regulation of the pro-B-cell-specific enhancer of the Id1 gene involves the C/EBP family of proteins. Mol Cell Biol. 1997;17:844-50 pubmed
western blot; human western blot; mouse	Wang X, Lawson B, Brewer J, Zinszner H, Sanjay A, Mi L, et al. Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol. 1996;16:4273-80 pubmed
immunoprecipitation; mouse western blot; mouse	Wang X, Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science. 1996;272:1347-9 pubmed
western blot; mouse	Batchvarova N, Wang X, Ron D. Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). EMBO J. 1995;14:4654-61 pubmed
	Mekhael O, Revill S, Hayat A, Cass S, MACDONALD K, Vierhout M, et al. Myeloid-specific deletion of activating transcription factor 6 alpha increases CD11b+ macrophage subpopulations and aggravates lung fibrosis. Immunol Cell Biol. 2023;101:412-427 pubmed publisher
	Chandrasekaran R, Bruno S, Mark Z, Walzer J, Caffry S, Gold C, et al. Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice. Am J Physiol Lung Cell Mol Physiol. 2023;324:L141-L153 pubmed publisher
	Dolatabadi S, Jonasson E, Andersson L, Luna Santamar xed a M, Lind xe9 n M, xd6 sterlund T, et al. FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma. Front Oncol. 2022;12:816894 pubmed publisher
	Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, et al. Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress. Cell Prolif. 2021;54:e13133 pubmed publisher
	Zhao S, Chen W, Li W, Yu W, Li S, Rao T, et al. LncRNA TUG1 attenuates ischaemia-reperfusion-induced apoptosis of renal tubular epithelial cells by sponging miR-144-3p via targeting Nrf2. J Cell Mol Med. 2021;25:9767-9783 pubmed publisher
	Fresia D, Cannizzaro E, Borgo A, Roduit R. GSH-Independent Induction of ER Stress during Hypoglycaemia in the Retinal Cells of Mice. J Clin Med. 2021;10: pubmed publisher
	Zhang X, Hu X, Wang H, Kan W, Xu L, Wang Z, et al. Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma. Acta Pharmacol Sin. 2020;: pubmed publisher
	Chen L, Xia Y, Shen S, Tang J, Chen J, Qian K, et al. Syntaxin 17 inhibits ischemic neuronal injury by resuming autophagy flux and ameliorating endoplasmic reticulum stress. Free Radic Biol Med. 2020;160:319-333 pubmed publisher
	Timberlake Ii M, Roy B, Dwivedi Y. A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus. Mol Neurobiol. 2019;: pubmed publisher
	Kim J, Kim B, Kim D, Jeong Y, Jeong S, Na Y, et al. Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer. Cancers (Basel). 2019;11: pubmed publisher
	Nakada E, Bhakta N, Korwin Mihavics B, Kumar A, Chamberlain N, Bruno S, et al. Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers. JCI Insight. 2019;4: pubmed publisher
	Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, et al. FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex. EMBO Rep. 2019;20: pubmed publisher
	Nakandakari S, Muñoz V, Kuga G, Gaspar R, Sant Ana M, Pavan I, et al. Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice. Brain Behav Immun. 2019;79:284-293 pubmed publisher
	Delbrel E, Soumare A, Naguez A, Label R, Bernard O, Bruhat A, et al. HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis. Sci Rep. 2018;8:17939 pubmed publisher
	Siegert A, Garcia Díaz Barriga G, Esteve Codina A, Navas Madroñal M, Gorbenko del Blanco D, Alberch J, et al. A FBN1 3'UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome. Biochim Biophys Acta Mol Basis Dis. 2019;1865:107-114 pubmed publisher
	Maciel M, Hernández Barrientos D, Herrera I, Selman M, Pardo A, Cabrera S. Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. Aging (Albany NY). 2018;10:2098-2112 pubmed publisher
	Cueno M, Ochiai K. Gingival Periodontal Disease (PD) Level-Butyric Acid Affects the Systemic Blood and Brain Organ: Insights Into the Systemic Inflammation of Periodontal Disease. Front Immunol. 2018;9:1158 pubmed publisher
	Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, et al. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Mol Neurodegener. 2018;13:4 pubmed publisher
	Verma S, Pillay P, Naicker T, Moodley J, Mackraj I. Placental hypoxia inducible factor -1? & CHOP immuno-histochemical expression relative to maternal circulatory syncytiotrophoblast micro-vesicles in preeclamptic and normotensive pregnancies. Eur J Obstet Gynecol Reprod Biol. 2018;220:18-24 pubmed publisher
	Jain A, ZODE G, Kasetti R, Ran F, Yan W, Sharma T, et al. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proc Natl Acad Sci U S A. 2017;114:11199-11204 pubmed publisher
	Zhang W, Zhong W, Sun Q, Sun X, Zhou Z. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice. Sci Rep. 2017;7:8976 pubmed publisher
	Kilaparty S, Agarwal R, Singh P, Kannan K, Ali N. Endoplasmic reticulum stress-induced apoptosis accompanies enhanced expression of multiple inositol polyphosphate phosphatase 1 (Minpp1): a possible role for Minpp1 in cellular stress response. Cell Stress Chaperones. 2016;21:593-608 pubmed publisher
	Ying R, Wang X, Yang Y, Gu Z, Mai J, Qiu Q, et al. Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway. Life Sci. 2016;144:208-17 pubmed publisher
	Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, BiÃ¨che I, et al. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease. Brain. 2015;138:2383-98 pubmed publisher
	Sun Q, Zhong W, Zhang W, Li Q, Sun X, Tan X, et al. Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways. Am J Physiol Gastrointest Liver Physiol. 2015;308:G757-66 pubmed publisher
	Su C. Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mclâ€‘1 and Bclâ€‘xL and increasing Bax and CHOP protein expression. Int J Mol Med. 2014;34:1661-8 pubmed publisher
	Hull R, Zraika S, Udayasankar J, Aston Mourney K, Subramanian S, Kahn S. Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress. Diabetologia. 2009;52:1102-11 pubmed publisher
	Kuroda M, Wang X, Sok J, Yin Y, Chung P, Giannotti J, et al. Induction of a secreted protein by the myxoid liposarcoma oncogene. Proc Natl Acad Sci U S A. 1999;96:5025-30 pubmed
	Sok J, Wang X, Batchvarova N, Kuroda M, Harding H, Ron D. CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI. Mol Cell Biol. 1999;19:495-504 pubmed

product information

brand :

Novus

MasterCode :

NB600-1335

SKU :

NB600-1335

product name :

GADD153/CHOP Antibody (9C8)

Description :

The GADD153/CHOP Antibody (9C8) from NB600-1335 is a nb600-1335 antibody to . This antibody reacts with apoptosis, cell cycle and replication, dna repair, hypoxia, lipid and metabolism, neuroscience, unfolded protein response. The GADD153/CHOP Antibody (9C8) has been validated for the following applications: P35638, P35639.

target :

GADD153/CHOP

category :

Primary Antibodies

unit size :

0.1 ml (also 0.025 ml)

buffer :

Tris-Glycine, 0.15 M NaCl

clonality :

Monoclonal

clone :

9C8

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full length mouse CHOP/GADD153 [Swiss-Prot# P35639]

isotype :

IgG2b Kappa

purity :

Protein A purified

species :

Human, Mouse, Rat, Primate

theoretical molecular weight :

19 kDa

gene symbol :

DDIT3

images :

https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Flow-Cytometry-NB600-1335-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Flow-Cytometry-NB600-1335-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Flow-Cytometry-NB600-1335-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Simple-Western-NB600-1335-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Simple-Western-NB600-1335-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Simple-Western-NB600-1335-img0007.jpg

accessionNumbers :

P35638, P35639

applications :

Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Gel Super Shift Assays, Chromatin Immunoprecipitation (ChIP), Knockdown Validated

USD :

399 USD

alt names :

C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, CHOP-10, CHOP10 CEBPZ, CHOPC/EBP zeta, DDIT-3, DNA damage-inducible transcript 3 protein, DNA-damage-inducible transcript 3, GADD153, Growth arrest and DNA damage-inducible protein GADD153

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage