product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Ki67/MKI67 Antibody (SP6) - Unpurified
catalog :
NB600-1252
quantity :
0.5 ml (also 0.1 ml)
price :
579 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 62
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s1c
Kalamakis G, Brune D, Ravichandran S, Bolz J, Fan W, Ziebell F, et al. Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain. Cell. 2019;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 7b
Penna I, Gigoni A, Costa D, Vella S, Russo D, Poggi A, et al. The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells. Oncotarget. 2017;8:8189-8205 pubmed publisher
Kimishima Y, Misaka T, Yokokawa T, Wada K, Ueda K, Sugimoto K, et al. Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils. Nat Commun. 2021;12:6177 pubmed publisher
Young L, Morrison W, Campbell C, Moore E, Arsenault M, Dial A, et al. Loss of dystrophin expression in skeletal muscle is associated with senescence of macrophages and endothelial cells. Am J Physiol Cell Physiol. 2021;321:C94-C103 pubmed publisher
Hwang J, Kim W, Cho Y, Ryu J, Choi J, Jeong S, et al. Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer. Cell Death Dis. 2020;11:1034 pubmed publisher
Brizzolara A, Garbati P, Vella S, Calderoni M, Quattrone A, Tonini G, et al. Co-Administration of Fendiline Hydrochloride Enhances Chemotherapeutic Efficacy of Cisplatin in Neuroblastoma Treatment. Molecules. 2020;25: pubmed publisher
Singhal N, Bai M, Lee E, Luo S, Cook K, Ma D. Cytoprotection by a naturally occurring variant of ATP5G1 in Arctic ground squirrel neural progenitor cells. elife. 2020;9: pubmed publisher
Hvid H, Skydsgaard M, Jensen N, Viuff B, Jensen H, Oleksiewicz M, et al. Artificial Intelligence-Based Quantification of Epithelial Proliferation in Mammary Glands of Rats and Oviducts of Göttingen Minipigs. Toxicol Pathol. 2020;:192623320950633 pubmed publisher
Dani C, Gonçalves L, Proença I, Andrade F, Hilakivi Clarke L. Effects of Maternal Grape Juice Intake on Unfolded Protein Response in the Mammary Glands of Offspring of High Fat Diet Fed Rat Dams. Nutrients. 2020;12: pubmed publisher
Tibaldi E, Gnudi F, Panzacchi S, Mandrioli D, Vornoli A, Manservigi M, et al. Identification of aspartame-induced haematopoietic and lymphoid tumours in rats after lifetime treatment. Acta Histochem. 2020;122:151548 pubmed publisher
Nagai T, Ishida C, Nakamura T, Iwase A, Mori M, Murase T, et al. Focal Adhesion Kinase-Mediated Sequences, Including Cell Adhesion, Inflammatory Response, and Fibrosis, as a Therapeutic Target in Endometriosis. Reprod Sci. 2020;27:1400-1410 pubmed publisher
Gattlen C, Deftu A, Tonello R, Ling Y, Berta T, Ristoiu V, et al. The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain. Glia. 2020;: pubmed publisher
Paik E, Kim T, Cho Y, Ryu J, Choi J, Lee Y, et al. Preclinical assessment of the VEGFR inhibitor axitinib as a therapeutic agent for epithelial ovarian cancer. Sci Rep. 2020;10:4904 pubmed publisher
Ueha R, Ueha S, Kondo K, Nishijima H, Yamasoba T. Effects of Cigarette Smoke on the Nasal Respiratory and Olfactory Mucosa in Allergic Rhinitis Mice. Front Neurosci. 2020;14:126 pubmed publisher
Dufresne S, Gueritat J, Chiavassa S, Noblet C, Assi M, Rioux Leclercq N, et al. Exercise training improves radiotherapy efficiency in a murine model of prostate cancer. FASEB J. 2020;34:4984-4996 pubmed publisher
Kim J, Cho Y, Ryu J, Hwang I, Han H, Ahn H, et al. CDK7 is a reliable prognostic factor and novel therapeutic target in epithelial ovarian cancer. Gynecol Oncol. 2020;156:211-221 pubmed publisher
Minakawa A, Fukuda A, Sato Y, Kikuchi M, Kitamura K, Wiggins R, et al. Podocyte hypertrophic stress and detachment precedes hyperglycemia or albuminuria in a rat model of obesity and type2 diabetes-associated nephropathy. Sci Rep. 2019;9:18485 pubmed publisher
Gülcüler Balta G, Monzel C, Kleber S, Beaudouin J, Balta E, Kaindl T, et al. 3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival. Cell Rep. 2019;29:2295-2306.e6 pubmed publisher
Nama S, Muhuri M, Di Pascale F, Quah S, Aswad L, Fullwood M, et al. MicroRNA-138 is a Prognostic Biomarker for Triple-Negative Breast Cancer and Promotes Tumorigenesis via TUSC2 repression. Sci Rep. 2019;9:12718 pubmed publisher
Hayashi M, Madokoro H, Yamada K, Nishida H, Morimoto C, Sakamoto M, et al. Novel Antibody-Drug Conjugate with Anti-CD26 Humanized Monoclonal Antibody and Transcription Factor IIH (TFIIH) Inhibitor, Triptolide, Inhibits Tumor Growth via Impairing mRNA Synthesis. Cancers (Basel). 2019;11: pubmed publisher
Nørgaard S, Briand F, Sand F, Galsgaard E, Søndergaard H, Sørensen D, et al. Nephropathy in diabetic db/db mice is accelerated by high protein diet and improved by the SGLT2 inhibitor dapagliflozin. Eur J Pharmacol. 2019;860:172537 pubmed publisher
Winham C, Le T, Jellison E, Silver A, Levesque A, Koob A. γ-Synuclein Induces Human Cortical Astrocyte Proliferation and Subsequent BDNF Expression and Release. Neuroscience. 2019;410:41-54 pubmed publisher
Pasca A, Park J, Shin H, Qi Q, Revah O, Krasnoff R, et al. Human 3D cellular model of hypoxic brain injury of prematurity. Nat Med. 2019;: pubmed publisher
Goto T, Ueha R, Sato T, Fujimaki Y, Nito T, Yamasoba T. Single, high-dose local injection of bFGF improves thyroarytenoid muscle atrophy after paralysis. Laryngoscope. 2019;: pubmed publisher
Kato N, Iwase A, Ishida C, Nagai T, Mori M, Bayasula -, et al. Upregulation of Fibroblast Growth Factors Caused by Heart and Neural Crest Derivatives Expressed 2 Suppression in Endometriotic Cells: A Possible Therapeutic Target in Endometriosis. Reprod Sci. 2019;26:979-987 pubmed publisher
Ueha R, Kondo K, Ueha S, Yamasoba T. Dose-Dependent Effects of Insulin-Like Growth Factor 1 in the Aged Olfactory Epithelium. Front Aging Neurosci. 2018;10:385 pubmed publisher
Ueha R, Ueha S, Kondo K, Kikuta S, Yamasoba T. Cigarette Smoke-Induced Cell Death Causes Persistent Olfactory Dysfunction in Aged Mice. Front Aging Neurosci. 2018;10:183 pubmed publisher
Burks J, Nadella S, Mahmud A, Mankongpaisarnrung C, Wang J, Hahm J, et al. Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer. Cell Mol Gastroenterol Hepatol. 2018;6:17-32 pubmed publisher
Ueha R, Shichino S, Ueha S, Kondo K, Kikuta S, Nishijima H, et al. Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa. Front Aging Neurosci. 2018;10:86 pubmed publisher
Pucci Molineris M, González Polo V, Perez F, Ramisch D, Rumbo M, Gondolesi G, et al. Paneth and Intestinal Stem Cells Preserve their Functional Integrity during Worsening of Acute Cellular Rejection in Small Bowel Transplantation. Am J Transplant. 2017;: pubmed publisher
Nishizono R, Kikuchi M, Wang S, Chowdhury M, Nair V, HARTMAN J, et al. FSGS as an Adaptive Response to Growth-Induced Podocyte Stress. J Am Soc Nephrol. 2017;28:2931-2945 pubmed publisher
Sumis A, Cook K, Andrade F, Hu R, Kidney E, Zhang X, et al. Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk. Endocr Relat Cancer. 2016;23:839-56 pubmed publisher
Kalliokoski S, Piqueras V, Frías R, Sulic A, Määttä J, Kähkönen N, et al. Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice. Amino Acids. 2017;49:529-540 pubmed publisher
Rath S, Deb M, Sengupta D, Kari V, Kar S, Parbin S, et al. Silencing of ZRF1 impedes survival of estrogen receptor positive MCF-7 cells and potentiates the effect of curcumin. Tumour Biol. 2016;37:12535-12546 pubmed
Ueha R, Ueha S, Sakamoto T, Kanaya K, Suzukawa K, Nishijima H, et al. Cigarette Smoke Delays Regeneration of the Olfactory Epithelium in Mice. Neurotox Res. 2016;30:213-24 pubmed publisher
Migita H, Yoshitake S, Tange Y, Choijookhuu N, Hishikawa Y. Hyperbaric Oxygen Therapy Suppresses Apoptosis and Promotes Renal Tubular Regeneration After Renal Ischemia/Reperfusion Injury in Rats. Nephrourol Mon. 2016;8:e34421 pubmed publisher
Ueha R, Ueha S, Kondo K, Sakamoto T, Kikuta S, Kanaya K, et al. Damage to Olfactory Progenitor Cells Is Involved in Cigarette Smoke-Induced Olfactory Dysfunction in Mice. Am J Pathol. 2016;186:579-86 pubmed publisher
Falkenberg N, Höfig I, Rosemann M, Szumielewski J, Richter S, Schorpp K, et al. Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer. Cancer Med. 2016;5:703-10 pubmed publisher
Du Z, Bondarenko O, Wang D, Rouabhia M, Zhang Z. Ex Vivo Assay of Electrical Stimulation to Rat Sciatic Nerves: Cell Behaviors and Growth Factor Expression. J Cell Physiol. 2016;231:1301-12 pubmed publisher
Jang H, Padanilam B. Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol. 2015;309:F540-50 pubmed publisher
Vesci L, Carollo V, Roscilli G, Aurisicchio L, Ferrara F, Spagnoli L, et al. Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance. Oncol Rep. 2015;34:1146-52 pubmed publisher
Tukler Henriksson J, Coursey T, Corry D, de Paiva C, Pflugfelder S. IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci. 2015;56:4186-97 pubmed publisher
Kim L, Wong L, Amarnani D, Bigger Allen A, Hu Y, Marko C, et al. Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Mol Vis. 2015;21:673-87 pubmed
Cage T, Chanthery Y, Chesler L, Grimmer M, Knight Z, Shokat K, et al. Downregulation of MYCN through PI3K Inhibition in Mouse Models of Pediatric Neural Cancer. Front Oncol. 2015;5:111 pubmed publisher
Schevzov G, Kee A, Wang B, Sequeira V, Hook J, Coombes J, et al. Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments. Mol Biol Cell. 2015;26:2475-90 pubmed publisher
Braks J, Spiegelberg L, Koljenovic S, Ridwan Y, Keereweer S, Kanaar R, et al. Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma. Mol Imaging Biol. 2015;17:633-42 pubmed publisher
Martinez Useros J, Rodriguez Remirez M, Borrero Palacios A, Moreno I, Cebrian A, Gómez del Pulgar T, et al. DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer. BMC Cancer. 2014;14:965 pubmed publisher
Kalliokoski S, Caja S, Frias R, Laurila K, Koskinen O, Niemela O, et al. Injection of celiac disease patient sera or immunoglobulins to mice reproduces a condition mimicking early developing celiac disease. J Mol Med (Berl). 2015;93:51-62 pubmed publisher
Papazoglou I, Jean A, Gertler A, Taouis M, Vacher C. Hippocampal GSK3β as a Molecular Link Between Obesity and Depression. Mol Neurobiol. 2015;52:363-74 pubmed publisher
Orticello M, Fiore M, Totta P, Desideri M, Barisic M, Passeri D, et al. N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics. Oncogene. 2015;34:3325-35 pubmed publisher
Olauson H, Lindberg K, Amin R, Sato T, Jia T, Goetz R, et al. Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion. PLoS Genet. 2013;9:e1003975 pubmed publisher
Pusic A, Kraig R. Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination. Glia. 2014;62:284-99 pubmed publisher
Vulpio C, Bossola M, Di Stasio E, Tazza L, Silvestri P, Fadda G. Histology and immunohistochemistry of the parathyroid glands in renal secondary hyperparathyroidism refractory to vitamin D or cinacalcet therapy. Eur J Endocrinol. 2013;168:811-9 pubmed publisher
Yee K, Li Y, Redding K, Iwatsuki K, Margolskee R, Jiang P. Lgr5-EGFP marks taste bud stem/progenitor cells in posterior tongue. Stem Cells. 2013;31:992-1000 pubmed publisher
Hua K, Schindler M, McQuail J, Forbes M, Riddle D. Regionally distinct responses of microglia and glial progenitor cells to whole brain irradiation in adult and aging rats. PLoS ONE. 2012;7:e52728 pubmed publisher
Kaenel P, Antonijevic M, Richter S, Küchler S, Sutter N, Wotzkow C, et al. Deregulated ephrin-B2 signaling in mammary epithelial cells alters the stem cell compartment and interferes with the epithelial differentiation pathway. Int J Oncol. 2012;40:357-69 pubmed publisher
Pageau S, Sazonova O, Wong J, Soto A, Sonnenschein C. The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture. Biomaterials. 2011;32:7169-80 pubmed publisher
Swartling F, Grimmer M, Hackett C, Northcott P, Fan Q, Goldenberg D, et al. Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010;24:1059-72 pubmed publisher
Zambon A. Use of the Ki67 promoter to label cell cycle entry in living cells. Cytometry A. 2010;77:564-70 pubmed publisher
Li J, Reed S, Johnson S. Hepatocyte growth factor (HGF) signals through SHP2 to regulate primary mouse myoblast proliferation. Exp Cell Res. 2009;315:2284-92 pubmed publisher
Koya V, Lu S, Sun Y, Purich D, Atkinson M, Li S, et al. Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy. Diabetes. 2008;57:757-69 pubmed
Frirdich E, Lindner B, Holst O, Whitfield C. Overexpression of the waaZ gene leads to modification of the structure of the inner core region of Escherichia coli lipopolysaccharide, truncation of the outer core, and reduction of the amount of O polysaccharide on the cell surface. J Bacteriol. 2003;185:1659-71 pubmed
product information
brand :
Novus
master code :
NB600-1252
SKU :
NB600-1252
product name :
Ki67/MKI67 Antibody (SP6) - Unpurified
description :
The Ki67/MKI67 Antibody (SP6) - Unpurified from NB600-1252 is a nb600-1252 antibody to . This antibody reacts with breast cancer, cancer, cell biology, cell cycle and replication, cellular markers, chromatin research, mitotic regulators, neuroscience.
target :
Ki67/MKI67
category :
Primary Antibodies
unit sizes :
0.5 ml (also 0.1 ml)
buffer :
Tissue culture supernatant
clonality :
Monoclonal
clone :
SP6
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen for this unpurified KI67/MKI67 Antibody (SP6) was made using a synthetic peptide from the C-Terminus of Human KI67/MKI67.
isotype :
IgG
purity :
Tissue culture supernatant
species :
Human, Mouse, Rat
theoretical molecular weight :
359 kDa
gene symbol :
MKI67
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, In vivo assay, Knockdown Validated
USD :
579 USD
alt names :
antigen identified by monoclonal Ki-67, antigen KI-67, Antigen Ki67, Ki67, Ki-67, KIA, Marker Of Proliferation Ki-67, MIB-, MIB-1, PPP1R105, Proliferation Marker Protein Ki-67, proliferation-related Ki-67 antigen, Protein Phosphatase 1, Regulatory Subunit 105
storage :
Store at 4C.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.