product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Caspase-3 Antibody
catalog :
NB600-1235
quantity :
0.5 ml (also 0.1 ml)
price :
609 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 44
Reference
Kavukcu S, Ensario x11f lu H, Karab x131 y x131 k H, Vatansever H, T xfc rkmen H. Cell Death Mechanism of Organometallic Ruthenium(II) and Iridium(III) Arene Complexes on HepG2 and Vero Cells. ACS Omega. 2023;8:37549-37563 pubmed publisher
Herrera L, Johnson R, McGlynn K, Gibbs Z, Davis A, Whitehurst A. The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks. J Biol Chem. 2023;299:105348 pubmed publisher
Abdelmaksoud H, Osman E, Abdel Hameed S, Aboushousha T, Naggar H. In vivo evaluation of anticryptosporidial effects of wheat germ extracts in immunocompromised mice. J Parasit Dis. 2022;46:833-844 pubmed publisher
Cheng Y, Shi L, Mao H, Xue Z, Liu S, Qiu Z, et al. The Effect of Sevoflurane Anesthesia on the Biomarkers of Neural Injury in the Prefrontal Cortex of Aged Marmosets. Front Aging Neurosci. 2022;14:918640 pubmed publisher
Eskiler G, Turna O, Ozkan A, Baykal A, Gurgen H, Erk B, et al. The response of the canine mammary simple carcinoma and carcinosarcoma cells to 5-aminolaevulinic acid-based photodynamic therapy: An in vitro study. J Photochem Photobiol B. 2022;234:112509 pubmed publisher
Amer S, El Araby D, Tartor H, Farahat M, Goda N, Farag M, et al. Long-Term Feeding with Curcumin Affects the Growth, Antioxidant Capacity, Immune Status, Tissue Histoarchitecture, Immune Expression of Proinflammatory Cytokines, and Apoptosis Indicators in Nile Tilapia, Oreochromis niloticus. Antioxidants (Basel). 2022;11: pubmed publisher
Mike J, Wu K, White Y, Pathipati P, Ndjamen B, Hutchings R, et al. Defining Longer-Term Outcomes in an Ovine Model of Moderate Perinatal Hypoxia-Ischemia. Dev Neurosci. 2022;44:277-294 pubmed publisher
Tanyeli A, Guzel Erdogan D, Comaklı S, Polat E, Güler M, Eraslan E, et al. Therapeutic effects of apocynin on ovarian ischemia-reperfusion induced lung injury. Biotech Histochem. 2022;97:536-545 pubmed publisher
G xfc ler M, Tanyeli A, Erdo x11f an D, Eraslan E, xc7 omakl x131 S, Polat E, et al. Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation. Iran J Basic Med Sci. 2021;24:935-942 pubmed publisher
Iwai H, Ataka K, Suzuki H, Dhar A, Kuramoto E, Yamanaka A, et al. Tissue-resident M2 macrophages directly contact primary sensory neurons in the sensory ganglia after nerve injury. J Neuroinflammation. 2021;18:227 pubmed publisher
Ibrahim Fouad G, Ahmed K. The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats. Tissue Cell. 2021;73:101612 pubmed publisher
Iskender H, Yenice G, Terim Kapakin K, Dokumacioglu E, Sevim C, Hayirli A, et al. Effects of high fructose diet on lipid metabolism and the hepatic NF-κB/ SIRT-1 pathway. Biotech Histochem. 2021;:1-9 pubmed publisher
Goto T, Kuramoto E, Dhar A, Wang R, Seki H, Iwai H, et al. Neurodegeneration of Trigeminal Mesencephalic Neurons by the Tooth Loss Triggers the Progression of Alzheimer's Disease in 3×Tg-AD Model Mice. J Alzheimers Dis. 2020;76:1443-1459 pubmed publisher
Varmazyari A, Taghizadehghalehjoughi A, Sevim C, Baris O, Eser G, Yildirim S, et al. Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies. Toxicol Rep. 2020;7:637-648 pubmed publisher
Liu K, Yu X, Sun T, Wang Y, Chen M, Su Y, et al. Effects of seawater immersion on open traumatic brain injury in rabbit model. Brain Res. 2020;1743:146903 pubmed publisher
Wang F, Wang Q, Zhu M, Sun Q. Foxo3a aggravates inflammation and induces apoptosis in IL-1-treated rabbit chondrocytes via positively regulating tenascin-c. Folia Histochem Cytobiol. 2020;58:1-8 pubmed publisher
Deniz G, Laloglu E, Altun S, Yigit N, Gezer A. Antioxidant and anti-apoptotic effects of vitexilactone on cisplatin-induced nephrotoxicity in rats. Biotech Histochem. 2020;95:381-388 pubmed publisher
Maremanda K, Sundar I, Rahman I. Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. Toxicol Appl Pharmacol. 2019;385:114788 pubmed publisher
Reynolds J, Henwood M, Turtle J, Baine R, Johnston D, Grau J. Brain-Dependent Processes Fuel Pain-Induced Hemorrhage After Spinal Cord Injury. Front Syst Neurosci. 2019;13:44 pubmed publisher
Ömür A, Yildirim B, Saglam Y, Çomaklı S, Ozkaraca M. Activity of resveratrol on the influence of aflatoxin B1 on the testes of Sprague dawley rats. Pol J Vet Sci. 2019;22:313-320 pubmed publisher
Navas Madroñal M, Rodriguez C, Kassan M, Fite J, Escudero J, Cañes L, et al. Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm. Clin Sci (Lond). 2019;133:1421-1438 pubmed publisher
Sevim C, Comaklı S, Taghizadehghalehjoughi A, Ozkaraca M, Mesnage R, Kovatsi L, et al. An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas. Toxicol Rep. 2019;6:42-50 pubmed publisher
Zhong X, Cui P, Cai Y, Wang L, He X, Long P, et al. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. Cell Metab. 2019;29:979-992.e4 pubmed publisher
Pan J, Tang F, Xiong F, Xiong L, Zeng P, Wang B, et al. APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress. Cell Death Dis. 2018;9:1077 pubmed publisher
Turtle J, Strain M, Reynolds J, Huang Y, Lee K, Henwood M, et al. Pain Input After Spinal Cord Injury (SCI) Undermines Long-Term Recovery and Engages Signal Pathways That Promote Cell Death. Front Syst Neurosci. 2018;12:27 pubmed publisher
Tamma R, Ruggieri S, Annese T, Simone G, Mangia A, Rega S, et al. Bcl6/p53 expression, macrophages/mast cells infiltration and microvascular density in invasive breast carcinoma. Oncotarget. 2018;9:22727-22740 pubmed publisher
Onk D, Onk O, Erol H, Ozkaraca M, Comaklı S, Ayazoglu T, et al. Effect of melatonin on antioxidant capacity, ?nflammation and apoptotic cell death in lung tissue of diabetic rats. Acta Cir Bras. 2018;33:375-385 pubmed publisher
Tarpey M, Davy K, McMillan R, Bowser S, Halliday T, Boutagy N, et al. Skeletal muscle autophagy and mitophagy in endurance-trained runners before and after a high-fat meal. Mol Metab. 2017;6:1597-1609 pubmed publisher
Kandimalla R, Manczak M, Yin X, Wang R, Reddy P. Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease. Hum Mol Genet. 2018;27:30-40 pubmed publisher
Vartanian V, Tumová J, Dobrzyn P, Dobrzyn A, Nakabeppu Y, Lloyd R, et al. 8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle. PLoS ONE. 2017;12:e0181687 pubmed publisher
Altun S, Özdemir S, Arslan H. Histopathological effects, responses of oxidative stress, inflammation, apoptosis biomarkers and alteration of gene expressions related to apoptosis, oxidative stress, and reproductive system in chlorpyrifos-exposed common carp (Cyprinus carpio L.). Environ Pollut. 2017;230:432-443 pubmed publisher
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
Chan Y, Saad S, Al Odat I, Oliver B, Pollock C, Jones N, et al. Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers. Front Mol Neurosci. 2017;10:33 pubmed publisher
Xu S, Wang P, Zhang H, Gong G, Gutiérrez Cortés N, Zhu W, et al. CaMKII induces permeability transition through Drp1 phosphorylation during chronic ?-AR stimulation. Nat Commun. 2016;7:13189 pubmed publisher
Chen H, Chan Y, Nguyen L, Mao Y, de Rosa A, Beh I, et al. Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations. Clin Exp Pharmacol Physiol. 2016;43:1107-1114 pubmed publisher
Aksu E, Kandemir F, Altun S, Kucukler S, Comaklı S, Omür A. Ameliorative Effect of Carvacrol on Cisplatin-Induced Reproductive Damage in Male Rats. J Biochem Mol Toxicol. 2016;30:513-520 pubmed publisher
Lennon F, Cianci G, Kanteti R, Riehm J, Arif Q, Poroyko V, et al. Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma. Sci Rep. 2016;6:24578 pubmed publisher
Aksu E, Özkaraca M, Kandemir F, Ömür A, Eldutar E, Küçükler S, et al. Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress. Andrologia. 2016;48:1145-1154 pubmed publisher
Hunziker E, Lippuner K, Keel M, Shintani N. Novel organ-slice culturing system to simulate meniscal repair: Proof of concept using a synovium-based pool of meniscoprogenitor cells. J Orthop Res. 2016;34:1588-96 pubmed publisher
Zhang M, Sun T, Jian C, Lei L, Han P, Lv Q, et al. Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish. PLoS ONE. 2015;10:e0132567 pubmed publisher
De Souza P, Balasubramanian K, Njoku C, Smith N, Gillespie D, Schwager A, et al. OKN-007 decreases tumor necrosis and tumor cell proliferation and increases apoptosis in a preclinical F98 rat glioma model. J Magn Reson Imaging. 2015;42:1582-91 pubmed publisher
Kandemir F, Ozkaraca M, Yildirim B, Hanedan B, Kırbas A, Kilic K, et al. Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats. Ren Fail. 2015;37:518-25 pubmed publisher
Palubinsky A, Stankowski J, Kale A, Codreanu S, Singer R, Liebler D, et al. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Antioxid Redox Signal. 2015;23:535-49 pubmed publisher
Buyuklu M, Kandemir F, Ozkaraca M, Set T, Bakirci E, Topal E, et al. Benefical effects of lycopene against contrast medium-induced oxidative stress, inflammation, autophagy, and apoptosis in rat kidney. Hum Exp Toxicol. 2015;34:487-96 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB600-1235
SKU :
NB600-1235
product name :
Caspase-3 Antibody
description :
The Caspase-3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Caspase-3. This antibody reacts with bovine,canine,fish,human,insect - drosophila melanogaster,mouse,primate,rabbit,rat. The Caspase-3 Antibody has been validated for the following applications: Immunohistochemistry-Frozen,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence.
target :
Caspase-3
unit size :
0.5 ml (also 0.1 ml)
category :
Primary Antibodies
buffer :
PBS (pH 7.4), 0.2% BSA, Tween-20
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This Caspase-3 Antibody was developed against a synthetic peptide corresponding to the cleavage site of human caspase 3 (amino acids 167-175), conjugated to KLH.
isotype :
IgG
purity :
Affinity purified
species :
Bovine,Canine,Drosophila melanogaster,Fish,Human,Mouse,Primate,Rabbit,Rat
specificity :
This reacts with the active form of Caspase 3 (17 kDa protein)
storage :
Store at 4C. Do not freeze.
theoretical molecular weight :
31.7 kDa
gene symbol :
CASP3
accessionNumbers :
P42574, P42574
applications :
Immunohistochemistry-Frozen,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence
USD :
599
USD 2025 :
609 USD
alt names :
Apopain, apoptosis-related cysteine protease, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.