EpCAM/TROP1 Antibody (AUA1) - BSA Free | Novus Biologicals NB600-1182 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

EpCAM/TROP1 Antibody (AUA1) - BSA Free

catalog :

NB600-1182

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AUA1

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 32

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...	Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanová T, et al. Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cell Mol Life Sci. 2022;79:445 pubmed publisher
western blot; human	Aleksic T, Chitnis M, Perestenko O, Gao S, Thomas P, Turner G, et al. Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells. Cancer Res. 2010;70:6412-9 pubmed publisher
immunocytochemistry; human	Ntouroupi T, Ashraf S, McGregor S, Turney B, Seppo A, Kim Y, et al. Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope. Br J Cancer. 2008;99:789-95 pubmed publisher
flow cytometry; human	Conaghan P, Ashraf S, Tytherleigh M, Wilding J, Tchilian E, Bicknell D, et al. Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen. Br J Cancer. 2008;98:1217-25 pubmed publisher
western blot; human	Jordinson M, El Hariry I, Calnan D, Calam J, Pignatelli M. Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells. Gut. 1999;44:709-14 pubmed
immunocytochemistry; human immunohistochemistry; human	Anagnostaki E, Skarlos D, Tamvakis N, Psaropoulou P, Blana E, Bamias A, et al. Immunohistochemical and immunocytochemical study of bladder carcinomas using the epithelium-specific, tumour-associated monoclonal antibodies HMFG1 and AUA1. Br J Cancer Suppl. 1990;10:52-6 pubmed
immunocytochemistry; human	Kocjan G, Sweeney E, Miller K, Bobrow L. AUA1: new immunocytochemical marker for detecting epithelial cells in body cavity fluids. J Clin Pathol. 1992;45:358-9 pubmed
	Augustine T, John P, Friedman T, Jiffry J, Guzik H, Mannan R, et al. Potentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer. Front Oncol. 2022;12:1018767 pubmed publisher
	Fan H, Atiya H, Wang Y, Pisanic T, Wang T, Shih I, et al. Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis. Cell Rep. 2020;33:108473 pubmed publisher
	de Vries M, Parma L, Peters H, Schepers A, Hamming J, Jukema J, et al. Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels. J Intern Med. 2019;285:59-74 pubmed publisher
	Chang Z, Wang Z, Shao D, Yue J, Xing H, Li L, et al. Shape Engineering Boosts Magnetic Mesoporous Silica Nanoparticle-Based Isolation and Detection of Circulating Tumor Cells. ACS Appl Mater Interfaces. 2018;10:10656-10663 pubmed publisher
	Albarenque S, Zwacka R, Mohr A. Both human and mouse mesenchymal stem cells promote breast cancer metastasis. Stem Cell Res. 2011;7:163-71 pubmed publisher
	Soares D, Battistella A, Rocca C, Matuo R, Henriques J, Larsen A, et al. Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906. Biochem J. 2011;437:63-73 pubmed publisher
	Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori A, Gerrits B, et al. MRE11 complex links RECQ5 helicase to sites of DNA damage. Nucleic Acids Res. 2009;37:2645-57 pubmed publisher
	Helmink B, Bredemeyer A, Lee B, Huang C, Sharma G, Walker L, et al. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. J Exp Med. 2009;206:669-79 pubmed publisher
	Ottini L, Falchetti M, Saieva C, De Marco M, Masala G, Zanna I, et al. MRE11 expression is impaired in gastric cancer with microsatellite instability. Carcinogenesis. 2004;25:2337-43 pubmed
	Giannini G, Rinaldi C, Ristori E, Ambrosini M, Cerignoli F, Viel A, et al. Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. Oncogene. 2004;23:2640-7 pubmed
	Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 2003;22:5612-21 pubmed
	Xu X, Stern D. NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J. 2003;17:1842-8 pubmed
	Lee J, Xu B, Lee C, Ahn J, Song M, Lee H, et al. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol Cancer Res. 2003;1:674-81 pubmed
	Celeste A, Fernandez Capetillo O, Kruhlak M, Pilch D, Staudt D, Lee A, et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol. 2003;5:675-9 pubmed
	Stewart G, Wang B, Bignell C, Taylor A, Elledge S. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature. 2003;421:961-6 pubmed
	Lukas C, Falck J, Bartkova J, Bartek J, Lukas J. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat Cell Biol. 2003;5:255-60 pubmed
	Xu X, Stern D. NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem. 2003;278:8795-803 pubmed
	Nakanishi K, Taniguchi T, Ranganathan V, New H, Moreau L, Stotsky M, et al. Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol. 2002;4:913-20 pubmed
	Stracker T, Carson C, Weitzman M. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature. 2002;418:348-52 pubmed
	Limoli C, Giedzinski E, Bonner W, Cleaver J. UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization. Proc Natl Acad Sci U S A. 2002;99:233-8 pubmed
	El Hariry I, Pignatelli M, Lemoine N. FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines. Br J Cancer. 2001;84:1656-63 pubmed
	Harfst E, Cooper S, Neubauer S, Distel L, Grawunder U. Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome. Mol Immunol. 2000;37:915-29 pubmed
	Lombard D, Guarente L. Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res. 2000;60:2331-4 pubmed
	Gatei M, Young D, Cerosaletti K, Desai Mehta A, Spring K, Kozlov S, et al. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat Genet. 2000;25:115-9 pubmed
	Wang Y, Cortez D, Yazdi P, Neff N, Elledge S, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 2000;14:927-39 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB600-1182

SKU :

NB600-1182

product name :

EpCAM/TROP1 Antibody (AUA1) - BSA Free

description :

The EpCAM/TROP1 Antibody (AUA1) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to EpCAM/TROP1. This antibody reacts with human. The EpCAM/TROP1 Antibody (AUA1) - BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,IF/IHC,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence.

target :

EpCAM/TROP1

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

AUA1

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

LoVo cell line preparation (Human).

isotype :

IgG1

purity :

Protein G purified

species :

Human

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

theoretical molecular weight :

35 kDa

gene symbol :

EPCAM

applications :

ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,IF/IHC,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

more info or order :

Novus Biologicals product webpage