product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CD34 Antibody (MEC 14.7)
catalog :
NB600-1071
quantity :
0.1 ml (also 0.025 ml)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MEC 14.7
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 50
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig s4
Costa B, Fletcher M, Boskovic P, Ivanova E, Eisemann T, Lohr S, et al. A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors. Cancers (Basel). 2021;13: pubmed publisher
  • flow cytometry; mouse; fig 2b
Wei L, Wang H, Yang F, Ding Q, Zhao J. Interleukin-17 potently increases non-small cell lung cancer growth. Mol Med Rep. 2016;13:1673-80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Scheerer N, Dehne N, Stockmann C, Swoboda S, Baba H, Neugebauer A, et al. Myeloid hypoxia-inducible factor-1α is essential for skeletal muscle regeneration in mice. J Immunol. 2013;191:407-14 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Savic R, He X, Fiel I, Schuchman E. Recombinant human acid sphingomyelinase as an adjuvant to sorafenib treatment of experimental liver cancer. PLoS ONE. 2013;8:e65620 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Lee Y, Morinaga H, Kim J, Lagakos W, Taylor S, Keshwani M, et al. The fractalkine/CX3CR1 system regulates β cell function and insulin secretion. Cell. 2013;153:413-25 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • flow cytometry; mouse
  • immunocytochemistry; mouse
Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira C, Stairs D, et al. A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008;118:3860-9 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Zheng Y, Du X, Wang W, Boucher M, Parimoo S, Stenn K. Organogenesis from dissociated cells: generation of mature cycling hair follicles from skin-derived cells. J Invest Dermatol. 2005;124:867-76 pubmed
  • flow cytometry; mouse
Dong Q, Bernasconi S, Lostaglio S, de Calmanovici R, Martin Padura I, Breviario F, et al. A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Arterioscler Thromb Vasc Biol. 1997;17:1599-604 pubmed
Çelikten M, Sahin H, Senturk G, Bilsel K, Pulatkan A, Kapıcıoğlu M, et al. The effect of platelet-rich fibrin, platelet-rich plasma, and concentrated growth factor in the repair of full thickness rotator cuff tears. J Shoulder Elbow Surg. 2023;: pubmed publisher
Liu Y, Zhou Y. Circ_0087960 stabilizes KDM5B by reducing SKP2 mediated ubiquitination degradation and promotes osteogenic differentiation in periodontal ligament stem cells. Regen Ther. 2022;19:122-130 pubmed publisher
Fj xe6 stad K, R xf8 mer A, Goitea V, Johansen A, Thorseth M, Carretta M, et al. Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment. Oncogene. 2022;41:1364-1375 pubmed publisher
Wang T, Bai J, Lu M, Huang C, Geng D, Chen G, et al. Engineering immunomodulatory and osteoinductive implant surfaces via mussel adhesion-mediated ion coordination and molecular clicking. Nat Commun. 2022;13:160 pubmed publisher
Lynch E, Robertson S, FitzGibbons C, Reilly M, Switalski C, Eckardt A, et al. Transcriptome analysis using patient iPSC-derived skeletal myocytes: Bet1L as a new molecule possibly linked to neuromuscular junction degeneration in ALS. Exp Neurol. 2021;345:113815 pubmed publisher
Zhou C, Zhou L, Liu J, Xu L, Xu Z, Chen Z, et al. Kidney extracellular matrix hydrogel enhances therapeutic potential of adipose-derived mesenchymal stem cells for renal ischemia reperfusion injury. Acta Biomater. 2020;115:250-263 pubmed publisher
Ho J, Balukoff N, Theodoridis P, Wang M, Krieger J, Schatz J, et al. A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism. Nat Commun. 2020;11:2677 pubmed publisher
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan N, et al. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness. J Clin Invest. 2020;: pubmed publisher
Chen J, Haller C, Jernigan F, Koerner S, Wong D, Wang Y, et al. Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists. Sci Adv. 2020;6:eaay8230 pubmed publisher
Niu Y, Bao L, Chen Y, Wang C, Luo M, Zhang B, et al. HIF-2-induced long non-coding RNA RAB11B-AS1 promotes hypoxia-mediated angiogenesis and breast cancer metastasis. Cancer Res. 2020;: pubmed publisher
Orlando I, Lafleur V, Storti F, Spielmann P, Crowther L, Santambrogio S, et al. Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression. Haematologica. 2019;: pubmed publisher
Schmid V, Lafleur V, Lombardi O, Li R, Salama R, Colli L, et al. Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer. Sci Rep. 2019;9:18768 pubmed publisher
Lauer V, Grampp S, PLATT J, Lafleur V, Lombardi O, Choudhry H, et al. Hypoxia drives glucose transporter 3 expression through HIF-mediated induction of the long non-coding RNA NICI. J Biol Chem. 2019;: pubmed publisher
Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, et al. Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. Cell Rep. 2019;29:89-103.e7 pubmed publisher
Louphrasitthiphol P, Ledaki I, Chauhan J, Falletta P, Siddaway R, Buffa F, et al. MITF controls the TCA cycle to modulate the melanoma hypoxia response. Pigment Cell Melanoma Res. 2019;32:792-808 pubmed publisher
Kolb R, Kluz P, Tan Z, Borcherding N, Bormann N, Vishwakarma A, et al. Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. Oncogene. 2019;38:2351-2363 pubmed publisher
Smythies J, Sun M, Masson N, Salama R, Simpson P, Murray E, et al. Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin. EMBO Rep. 2019;20: pubmed publisher
Rahman M, Thomas P. Molecular cloning and characterization of two ARNT (ARNT-1 and ARNT-2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77. Environ Toxicol. 2019;34:160-171 pubmed publisher
Sakurai R, Liu J, Wang Y, Torday J, Rehan V. Prevention of perinatal nicotine-induced bone marrow mesenchymal stem cell myofibroblast differentiation by augmenting the lipofibroblast phenotype. Clin Sci (Lond). 2018;132:2357-2368 pubmed publisher
Braun R, Chetty C, Balasubramaniam V, Centanni R, Haraldsdottir K, Hematti P, et al. Intraperitoneal injection of MSC-derived exosomes prevent experimental bronchopulmonary dysplasia. Biochem Biophys Res Commun. 2018;503:2653-2658 pubmed publisher
Rodrigues P, Patel S, Harewood L, Olan I, Vojtasova E, Syafruddin S, et al. NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discov. 2018;8:850-865 pubmed publisher
Kim Y, Seok S, Byun S, Kong B, Zhang Y, Guo G, et al. AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nat Commun. 2018;9:540 pubmed publisher
Tiana M, Acosta Iborra B, Puente Santamaría L, Hernansanz Agustín P, Worsley Hunt R, Masson N, et al. The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia. Nucleic Acids Res. 2017;: pubmed publisher
Kobayashi M, Morinibu A, Koyasu S, Goto Y, Hiraoka M, Harada H. A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes. FEBS J. 2017;284:3804-3816 pubmed publisher
Grampp S, Schmid V, Salama R, Lauer V, Kranz F, Platt J, et al. Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway. PLoS Genet. 2017;13:e1006872 pubmed publisher
Xu B, Li Y, Deng B, Liu X, Wang L, Zhu Q. Chitosan hydrogel improves mesenchymal stem cell transplant survival and cardiac function following myocardial infarction in rats. Exp Ther Med. 2017;13:588-594 pubmed publisher
Grampp S, Platt J, Lauer V, Salama R, Kranz F, Neumann V, et al. Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer. Nat Commun. 2016;7:13183 pubmed publisher
Kraus A, Grampp S, Goppelt Struebe M, Schreiber R, Kunzelmann K, Peters D, et al. P2Y2R is a direct target of HIF-1? and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells. Purinergic Signal. 2016;12:687-695 pubmed
Platt J, Salama R, Smythies J, Choudhry H, Davies J, Hughes J, et al. Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters. EMBO Rep. 2016;17:1410-1421 pubmed
Biktasova A, Dudimah D, Uzhachenko R, Park K, Akhter A, Arasada R, et al. Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy. Cancer Res. 2015;75:4728-41 pubmed publisher
Salama R, Masson N, Simpson P, Sciesielski L, Sun M, Tian Y, et al. Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer. PLoS ONE. 2015;10:e0134645 pubmed publisher
Long F, Si L, Long X, YANG B, Wang X, Zhang F. 2ME2 increase radiation-induced apoptosis of keloid fibroblasts by targeting HIF-1α in vitro. Australas J Dermatol. 2016;57:e32-8 pubmed publisher
Wong W, Richardson T, Seykora J, Cotsarelis G, Simon M. Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. J Invest Dermatol. 2015;135:454-461 pubmed publisher
Rataj F, Möller F, Jähne M, Hönscheid P, Zierau O, Vollmer G, et al. Progesterone, as well as 17?-estradiol, is important for regulating AHR battery homoeostasis in the rat uterus. Arch Toxicol. 2015;89:393-404 pubmed publisher
Borriello L, Montes M, Lepelletier Y, Leforban B, Liu W, Demange L, et al. Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model. Cancer Lett. 2014;349:120-7 pubmed publisher
Huang Y, Li I, Chueh S, Hueng D, Tai M, Liang C, et al. Mesenchymal stem cells from rat olfactory bulbs can differentiate into cells with cardiomyocyte characteristics. J Tissue Eng Regen Med. 2015;9:E191-201 pubmed publisher
Branco Price C, Zhang N, Schnelle M, Evans C, Katschinski D, Liao D, et al. Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success. Cancer Cell. 2012;21:52-65 pubmed publisher
Fiorina P, Pietramaggiori G, Scherer S, Jurewicz M, Mathews J, Vergani A, et al. The mobilization and effect of endogenous bone marrow progenitor cells in diabetic wound healing. Cell Transplant. 2010;19:1369-81 pubmed publisher
Sironi M, Conti A, Bernasconi S, Fra A, Pasqualini F, Nebuloni M, et al. Generation and characterization of a mouse lymphatic endothelial cell line. Cell Tissue Res. 2006;325:91-100 pubmed
Trempus C, Morris R, Bortner C, Cotsarelis G, Faircloth R, Reece J, et al. Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J Invest Dermatol. 2003;120:501-11 pubmed
Vecchi A, Massimiliano L, Ramponi S, Luini W, Bernasconi S, Bonecchi R, et al. Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells. J Leukoc Biol. 1999;66:489-94 pubmed
Garlanda C, Berthier R, Garin J, Stoppacciaro A, Ruco L, Vittet D, et al. Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34: a useful reage for identifying and characterizing blood vessels and hematopoietic precursors. Eur J Cell Biol. 1997;73:368-77 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB600-1071
SKU :
NB600-1071
product name :
CD34 Antibody (MEC 14.7)
description :
The CD34 Antibody (MEC 14.7) from Novus Biologicals is a rat monoclonal antibody to CD34. This antibody reacts with human,human (negative),mouse,rabbit,rat. The CD34 Antibody (MEC 14.7) has been validated for the following applications: ELISA,Immunohistochemistry,Immunoprecipitation,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.
target :
CD34
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
MEC 14.7
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rat
immunogen :
Murine transformed endothelioma cell line t-end.
isotype :
IgG2a
marker :
Hematopoietic Stem Cell Marker
purity :
Protein G purified
species :
Human,Human (Negative),Mouse,Rabbit,Rat
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
gene symbol :
CD34
applications :
ELISA,Immunohistochemistry,Immunoprecipitation,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence
USD :
459
USD 2025 :
459 USD
alt names :
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.