This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free
catalog :
NB600-1066-0.1mg
quantity :
0.1 mg
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PCG4.1
application :
western blot, ELISA, immunocytochemistry
citations: 22
Reference
Wang S, Heuler J, Wickramage I, Sun X. Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection. Microbiol Spectr. 2022;10:e0178821 pubmed publisher
Zhu D, Wang S, Sun X. FliW and CsrA Govern Flagellin (FliC) Synthesis and Play Pleiotropic Roles in Virulence and Physiology of Clostridioides difficile R20291. Front Microbiol. 2021;12:735616 pubmed publisher
Zhu D, Patabendige H, Tomlinson B, Wang S, Hussain S, Flores D, et al. Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in Clostridioides difficile R20291. Environ Microbiol. 2021;: pubmed publisher
Ahmed U, Shadid T, Larabee J, Ballard J. Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production. MBio. 2020;11: pubmed publisher
Oliveira P, Ribis J, Garrett E, Trzilova D, Kim A, Sekulovic O, et al. Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis. Nat Microbiol. 2020;5:166-180 pubmed publisher
Edwards A, Krall E, McBride S. Strain-Dependent RstA Regulation of Clostridioides difficile Toxin Production and Sporulation. J Bacteriol. 2020;202: pubmed publisher
Edwards A, Anjuwon Foster B, McBride S. RstA Is a Major Regulator of Clostridioides difficile Toxin Production and Motility. MBio. 2019;10: pubmed publisher
Daou N, Wang Y, Levdikov V, Nandakumar M, Livny J, Bouillaut L, et al. Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027. PLoS ONE. 2019;14:e0206896 pubmed publisher
Woods E, Edwards A, Childress K, Jones J, McBride S. The C. difficile clnRAB operon initiates adaptations to the host environment in response to LL-37. PLoS Pathog. 2018;14:e1007153 pubmed publisher
Anjuwon Foster B, Maldonado Vazquez N, Tamayo R. Characterization of Flagellum and Toxin Phase Variation in Clostridioides difficile Ribotype 012 Isolates. J Bacteriol. 2018;200: pubmed publisher
Kroh H, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi M, et al. Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. J Biol Chem. 2017;292:14401-14412 pubmed publisher
Anjuwon Foster B, Tamayo R. A genetic switch controls the production of flagella and toxins in Clostridium difficile. PLoS Genet. 2017;13:e1006701 pubmed publisher
Chandrasekaran R, Kenworthy A, Lacy D. Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis. PLoS Pathog. 2016;12:e1006070 pubmed publisher
Childress K, Edwards A, Nawrocki K, Anderson S, Woods E, McBride S. The Phosphotransfer Protein CD1492 Represses Sporulation Initiation in Clostridium difficile. Infect Immun. 2016;84:3434-3444 pubmed
Edwards A, Tamayo R, McBride S. A novel regulator controls Clostridium difficile sporulation, motility and toxin production. Mol Microbiol. 2016;100:954-71 pubmed publisher
Willing S, Richards E, Sempere L, Dale A, Cutting S, Fairweather N. Increased toxin expression in a Clostridium difficile mfd mutant. BMC Microbiol. 2015;15:280 pubmed publisher
McKee R, Mangalea M, Purcell E, Borchardt E, Tamayo R. The second messenger cyclic Di-GMP regulates Clostridium difficile toxin production by controlling expression of sigD. J Bacteriol. 2013;195:5174-85 pubmed publisher
Kolling G, Wu M, Warren C, Durmaz E, Klaenhammer T, Timko M, et al. Lactic acid production by Streptococcus thermophilus alters Clostridium difficile infection and in vitro Toxin A production. Gut Microbes. 2012;3:523-9 pubmed publisher
Aubry A, Hussack G, Chen W, Kuolee R, Twine S, Fulton K, et al. Modulation of toxin production by the flagellar regulon in Clostridium difficile. Infect Immun. 2012;80:3521-32 pubmed publisher
Vohra P, Poxton I. Comparison of toxin and spore production in clinically relevant strains of Clostridium difficile. Microbiology. 2011;157:1343-53 pubmed publisher
Goulding D, Thompson H, Emerson J, Fairweather N, Dougan G, Douce G. Distinctive profiles of infection and pathology in hamsters infected with Clostridium difficile strains 630 and B1. Infect Immun. 2009;77:5478-85 pubmed publisher
Dissanayake S, Olkhanud P, O Connell M, Carter A, French A, Camilli T, et al. Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 2008;68:10205-14 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB600-1066
SKU :
NB600-1066-0.1mg
product name :
Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free
Description :
The Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free from Novus is a mouse monoclonal antibody to Clostridium Difficile Toxin A. This antibody reacts with bacteria. The Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence.
target :
Clostridium Difficile Toxin A
category :
Primary Antibodies
unit size :
0.1 mg
buffer :
10mM Sodium Phosphate (pH 7.4) and 0.15M NaCl
clonality :
Monoclonal
clone :
PCG4.1
concentration :
1.16 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length protein A (C. difficile).
isotype :
IgG2a Kappa
purity :
Protein A purified
species :
Bacteria
specificity :
C
applications :
Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence
USD :
289 USD
alt names :
tcdA, toxA
storage :
Store at 4C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.