p70 S6 Kinase/S6K [p Thr389/412] Antibody | Novus Biologicals NB600-1049 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

p70 S6 Kinase/S6K [p Thr389/412] Antibody

catalog :

NB600-1049

quantity :

0.025 mg

price :

199 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

8C8

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 15

Reference
Gao K, Niu J, Dang X. Wnt-3a improves functional recovery through autophagy activation via inhibiting the mTOR signaling pathway after spinal cord injury. Neurosci Lett. 2020;737:135305 pubmed publisher
Zhang Q, Wei D, Tan M, Li H, Morgan M, Sun Y. Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras-PDAC model. Neoplasia. 2020;22:242-252 pubmed publisher
Lee H, Jung Y, Choi G, Kim J, Chae C, Lim J, et al. O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells. Cell Death Dis. 2019;10:590 pubmed publisher
Jabari S, Schrödl F, Kaser Eichberger A, Kofler B, Brehmer A. Alarin in different human intestinal epithelial cell types. Histochem Cell Biol. 2019;151:513-520 pubmed publisher
Cerrillo E, Moret I, Iborra M, Ramos D, Buso E, Tortosa L, et al. Alpha-defensins (?-Defs) in Crohn's disease: Decrease of ileal ?-Def 5 via permanent methylation and increase in plasma ?-Def 1-3 concentrations offering biomarker utility. Clin Exp Immunol. 2017;: pubmed publisher
Lee K, Lee S, Lee H, Choi G, Jung Y, Kim D, et al. Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death. Front Mol Neurosci. 2017;10:229 pubmed publisher
Múnera J, Sundaram N, Rankin S, Hill D, Watson C, Mahe M, et al. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell Stem Cell. 2017;21:51-64.e6 pubmed publisher
Liu T, Naito T, Liu Z, VanDussen K, Haritunians T, Li D, et al. LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients. JCI Insight. 2017;2:e91917 pubmed publisher
Liu T, Gurram B, Baldridge M, Head R, Lam V, Luo C, et al. Paneth cell defects in Crohn's disease patients promote dysbiosis. JCI Insight. 2016;1:e86907 pubmed publisher
Kim H, Kang U, Lee H, Jung J, Lee S, Yu M, et al. Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes. J Proteomics. 2012;75:2983-97 pubmed publisher
Jung J, Kim H, Yeom J, Yoo C, Shin J, Yoo J, et al. Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer. J Gastroenterol. 2012;47:37-48 pubmed publisher
Bukurova I, Nikitina S, Khankin S, Krasnov G, Lisitsin N, Karpov V, et al. [Identification of protein markers for serum diagnosis of cancer based on microRNA expression profiling]. Mol Biol (Mosk). 2011;45:376-81 pubmed
Wehkamp J, Chu H, Shen B, Feathers R, Kays R, Lee S, et al. Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues. FEBS Lett. 2006;580:5344-50 pubmed
Wehkamp J, Salzman N, Porter E, Nuding S, Weichenthal M, Petras R, et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A. 2005;102:18129-34 pubmed
Shen B, Porter E, Reynoso E, Shen C, Ghosh D, Connor J, et al. Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract. J Clin Pathol. 2005;58:687-94 pubmed

product information

brand :

Novus

master code :

NB600-1049

SKU :

NB600-1049-0.025mg

product name :

p70 S6 Kinase/S6K [p Thr389/412] Antibody

description :

The p70 S6 Kinase/S6K [p Thr389/412] Antibody from Novus Biologicals is a rabbit polyclonal antibody to p70 S6 Kinase/S6K. This antibody reacts with human, mouse, rat. The p70 S6 Kinase/S6K [p Thr389/412] Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

target :

p70 S6 Kinase/S6K

category :

Primary Antibodies

unit size :

0.025 mg

buffer :

PBS (pH 7.4), 150 mM EDTA, 50% glycerol

clonality :

Polyclonal

concentration :

0.5 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic phospho-peptide surrounding amino acids Thr389/412 of human p70 S6 Kinase/S6K

isotype :

IgG

purity :

Affinity purified

species :

Human, Mouse, Rat

specificity :

p70 S6 Kinase/S6K [p Thr389/412] Antibody detects endogenous levels of p70 S6 Kinase only when phosphorylated at Threonine 389/412

gene symbol :

RPS6KB1

catalog number base :

NB600-1049

accessionNumbers :

Q9UBS0, P23443, NP_003152, Q8BSK8, NP_001107806.1, P67999, NP_114191.1

applications :

Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

2020 USD :

199

2021 USD :

199 USD

alt names :

EC 2.7.11, EC 2.7.11.1, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6 kinase, alpha 1,70 kDa ribosomal protein S6 kinase 1, p70 S6 kinase, alpha 2, p70 S6KA, p70 S6K-alpha, p70(S6K)-alpha, p70-alpha, p70-S6K, P70S6K1, PS6K, ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase I, ribosomal protein S6 kinase, 70kD, polypeptide 1, ribosomal protein S6 kinase, 70kDa, polypeptide 1, S6K, S6K1p70-S6K 1, S6K-beta-1, serine/threonine kinase 14 alpha, Serine/threonine-protein kinase 14A, STK14A

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.