product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NPM1 Antibody (FC82291)
catalog :
NB600-1030
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
FC82291
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, ELISA, immunocytochemistry
more info or order :
citations: 3
Reference
Wang X, Fan D, Han Q, Liu Y, Miao H, Wang X, et al. Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. Cancer Discov. 2023;13:724-745 pubmed publisher
Luo H, Zhu G, Eshelman M, Fung T, Lai Q, Wang F, et al. HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia. Mol Cell. 2022;82:833-851.e11 pubmed publisher
Ibáñez Cabellos J, Seco Cervera M, Picher Latorre C, Pérez Machado G, García Gimenez J, Pallardo F. Acute depletion of telomerase components DKC1 and NOP10 induces oxidative stress and disrupts ribosomal biogenesis via NPM1 and activation of the P53 pathway. Biochim Biophys Acta Mol Cell Res. 2020;1867:118845 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB600-1030
SKU :
NB600-1030
product name :
NPM1 Antibody (FC82291)
description :
The NPM1 Antibody (FC82291) from Novus Biologicals is a mouse monoclonal antibody to NPM1. This antibody reacts with bovine,canine,donkey,hamster,human,monkey,mouse,rat. The NPM1 Antibody (FC82291) has been validated for the following applications: ELISA,Western Blot,Immunoblotting,Immunocytochemistry/ Immunofluorescence.
target :
NPM1
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
10mM PBS (pH 7.4) and 1.0% BSA
clonality :
Monoclonal
clone :
FC82291
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
rat B23 (nucleophosmin, NPM, numatrin). UniProt accession no. P06748.
isotype :
IgG1
purity :
Protein A or G purified
species :
Bovine,Canine,Donkey,Hamster,Human,Monkey,Mouse,Rat
specificity :
Detects both the phosphorylated and the unphosphorylated B23 molecule
storage :
Store at -20C. Avoid freeze-thaw cycles.
gene symbol :
NPM1
applications :
ELISA,Western Blot,Immunoblotting,Immunocytochemistry/ Immunofluorescence
USD :
449
USD 2025 :
469 USD
alt names :
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.