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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
beta-III Tubulin Antibody (TU-20) - BSA Free
catalog :
NB600-1018
quantity :
0.1 mg
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TU-20
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 31
Reference
Krach F, Wheeler E, Regensburger M, Boerstler T, Wend H, Vu A, et al. Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis. Acta Neuropathol. 2022;: pubmed publisher
Amar F, Corona C, Husson J, Liu J, Shelanski M, Greene L. Rapid ATF4 Depletion Resets Synaptic Responsiveness after cLTP. Eneuro. 2021;8: pubmed publisher
. Impaired kidney structure and function in spinal muscular atrophy. Neurol Genet. 2019;5:e353 pubmed publisher
Bächinger D, Egli H, Goosmann M, Monge Naldi A, Eckhard A. Immunolocalization of calcium sensing and transport proteins in the murine endolymphatic sac indicates calciostatic functions within the inner ear. Cell Tissue Res. 2019;378:163-173 pubmed publisher
Luchsinger L, Strikoudis A, Danzl N, Bush E, Finlayson M, Satwani P, et al. Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro. Cell Stem Cell. 2019;: pubmed publisher
Issa H, Hénaut L, Abdallah J, Boudot C, Lenglet G, Avondo C, et al. Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification. J Mol Cell Cardiol. 2019;129:2-12 pubmed publisher
Frees S, Breuksch I, Haber T, Bauer H, Chavez Munoz C, Raven P, et al. Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma. Oncotarget. 2018;9:15766-15779 pubmed publisher
Boudot C, Hénaut L, Thiem U, Geraci S, Galante M, Saldanha P, et al. Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation. Oncotarget. 2017;8:56460-56472 pubmed publisher
Martins F, Serrano J, Müller T, da Cruz e Silva O, Rebelo S. BRI2 Processing and Its Neuritogenic Role Are Modulated by Protein Phosphatase 1 Complexing. J Cell Biochem. 2017;118:2752-2763 pubmed publisher
Dai X, Perez P, Soria G, Scarinci N, Smoler M, Morsucci D, et al. External Ca2+ regulates polycystin-2 (TRPP2) cation currents in LLC-PK1 renal epithelial cells. Exp Cell Res. 2017;350:50-61 pubmed publisher
Koh J, Hogue J, Sosa J. A Novel Ex Vivo Method for Visualizing Live-Cell Calcium Response Behavior in Intact Human Tumors. PLoS ONE. 2016;11:e0161134 pubmed publisher
Koh J, Hogue J, Wang Y, DiSalvo M, Allbritton N, Shi Y, et al. Single-cell functional analysis of parathyroid adenomas reveals distinct classes of calcium sensing behaviour in primary hyperparathyroidism. J Cell Mol Med. 2016;20:351-9 pubmed publisher
Shilo V, Ben Dov I, Nechama M, Silver J, Naveh Many T. Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia. FASEB J. 2015;29:3964-76 pubmed publisher
Badizadegan K, Thomas A, Nagy N, Ndishabandi D, Miller S, Alessandrini A, et al. Presence of intramucosal neuroglial cells in normal and aganglionic human colon. Am J Physiol Gastrointest Liver Physiol. 2014;307:G1002-12 pubmed publisher
Szalat A, Shahar M, Shpitzen S, Nachmias B, Munter G, Gillis D, et al. Calcium-sensing receptor sequencing in 21 patients with idiopathic or familial parathyroid disorder: pitfalls and characterization of a novel I32 V loss-of-function mutation. Endocrine. 2015;48:444-53 pubmed publisher
Olauson H, Lindberg K, Amin R, Sato T, Jia T, Goetz R, et al. Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion. PLoS Genet. 2013;9:e1003975 pubmed publisher
Kong H, Wong M, Chan H, Lo S. Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex. J Proteome Res. 2013;12:5233-45 pubmed publisher
Walter S, Baruch A, Dong J, Tomlinson J, Alexander S, Janes J, et al. Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients. J Pharmacol Exp Ther. 2013;346:229-40 pubmed publisher
Toka H, Al Romaih K, Koshy J, Dibartolo S, Kos C, Quinn S, et al. Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol. 2012;23:1879-90 pubmed publisher
Yoo D, Kim W, Nam S, Chung J, Choi J, Yoon Y, et al. Chronic effects of pyridoxine in the gerbil hippocampal CA1 region after transient forebrain ischemia. Neurochem Res. 2012;37:1011-8 pubmed publisher
Galitzer H, Ben Dov I, Silver J, Naveh Many T. Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease. Kidney Int. 2010;77:211-8 pubmed publisher
Meir T, Levi R, Lieben L, Libutti S, Carmeliet G, Bouillon R, et al. Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology. Am J Physiol Renal Physiol. 2009;297:F1192-8 pubmed publisher
Jirasek T, Cipro S, Musilova A, Kubecova M, Mandys V. Expression of class III beta-tubulin in colorectal carcinomas: an immunohistochemical study using TU-20 & TuJ-1 antibody. Indian J Med Res. 2009;129:89-94 pubmed
Theodorou E, Dalembert G, Heffelfinger C, White E, Weissman S, Corcoran L, et al. A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation. Genes Dev. 2009;23:575-88 pubmed publisher
Alam M, Kirton J, Wilkinson F, Towers E, Sinha S, Rouhi M, et al. Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells. Cardiovasc Res. 2009;81:260-8 pubmed publisher
Katsetos C, Dráberová E, Smejkalová B, Reddy G, Bertrand L, de Chadarevian J, et al. Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells. Neurochem Res. 2007;32:1387-98 pubmed
Jirasek T, Písaríková E, Viklický V, Mandys V. Expression of class III beta-tubulin in malignant epithelial tumours: an immunohistochemical study using TU-20 and TuJ-1 antibodies. Folia Histochem Cytobiol. 2007;45:41-5 pubmed
Weston A, Absi M, Ward D, Ohanian J, Dodd R, Dauban P, et al. Evidence in favor of a calcium-sensing receptor in arterial endothelial cells: studies with calindol and Calhex 231. Circ Res. 2005;97:391-8 pubmed
Kukharskyy V, Sulimenko V, Macurek L, Sulimenko T, Dráberová E, Draber P. Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells. Exp Cell Res. 2004;298:218-28 pubmed
Peknicova J, Kubatova A, Sulimenko V, Draberova E, Viklicky V, Hozak P, et al. Differential subcellular distribution of tubulin epitopes in boar spermatozoa: recognition of class III beta-tubulin epitope in sperm tail. Biol Reprod. 2001;65:672-9 pubmed
Goldsmith P, Fan G, Ray K, Shiloach J, McPhie P, Rogers K, et al. Expression, purification, and biochemical characterization of the amino-terminal extracellular domain of the human calcium receptor. J Biol Chem. 1999;274:11303-9 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB600-1018
SKU :
NB600-1018
product name :
beta-III Tubulin Antibody (TU-20) - BSA Free
Description :
The beta-III Tubulin Antibody (TU-20) - BSA Free from Novus is a mouse monoclonal antibody to beta-III Tubulin. This antibody reacts with human, mouse, rat, canine. The beta-III Tubulin Antibody (TU-20) - BSA Free has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular).
target :
beta-III Tubulin
category :
Primary Antibodies
unit size :
0.1 mg
buffer :
PBS (pH 7.4)
clonality :
Monoclonal
clone :
TU-20
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.
isotype :
IgG1
purity :
Protein A purified
species :
Human, Mouse, Rat, Canine
specificity :
The antibody TU-20 recognizes C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human betaIII-tubulin
gene symbol :
TUBB3
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular)
USD :
399 USD
alt names :
beta-4, TUBB4 CFEOM3A, tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, tubulin, beta 3, TUJ1 antigen, TUJ-1 antigen
storage :
Store at 4C. Do not freeze.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.