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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ERCC1 Antibody (8F1) - BSA Free
catalog :
NB500-704
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8F1
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 18
Reference
Barone D, Iannuzzi C, Forte I, Ragosta M, Cuomo M, Dell Aquila M, et al. The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment. Front Oncol. 2023;13:1117262 pubmed publisher
Ma S, Venkatesh A, Langellotto F, Le Y, Hall M, Rüegg M, et al. Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. Exp Eye Res. 2015;135:1-13 pubmed publisher
Bepler G, Zinner R, Moon J, Calhoun R, Kernstine K, Williams C, et al. A phase 2 cooperative group adjuvant trial using a biomarker-based decision algorithm in patients with stage I non-small cell lung cancer (SWOG-0720, NCT00792701). Cancer. 2014;120:2343-51 pubmed publisher
Bepler G, Williams C, Schell M, Chen W, Zheng Z, Simon G, et al. Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer. J Clin Oncol. 2013;31:2404-12 pubmed publisher
Loganathan S, Kandala P, Gupta P, Srivastava S. Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model. PLoS ONE. 2012;7:e43577 pubmed publisher
Ozcan M, Dizdar O, Dincer N, Balci S, Guler G, Gok B, et al. Low ERCC1 expression is associated with prolonged survival in patients with bladder cancer receiving platinum-based neoadjuvant chemotherapy. Urol Oncol. 2013;31:1709-15 pubmed publisher
Sodja E, Knez L, Kern I, Ovčariček T, Sadikov A, Cufer T. Impact of ERCC1 expression on treatment outcome in small-cell lung cancer patients treated with platinum-based chemotherapy. Eur J Cancer. 2012;48:3378-85 pubmed publisher
Su C, Chu W, Lan K, Li C, Chao Y, Lin H, et al. Gemcitabine causes telomere attrition by stabilizing TRF2. Eur J Cancer. 2012;48:3465-74 pubmed publisher
Soltermann A, Kilgus Hawelski S, Behnke S, Storz M, Moch H, Bode B. Automated ERCC1 immunochemistry on hybrid cytology/tissue microarray of malignant effusions: evaluation of antibodies 8F1 and D-10. J Clin Bioinforma. 2011;1:25 pubmed publisher
Besse B, Massard C, Haddad V, Andre F, Dunant A, Pirker R, et al. ERCC1 influence on the incidence of brain metastases in patients with non-squamous NSCLC treated with adjuvant cisplatin-based chemotherapy. Ann Oncol. 2011;22:575-81 pubmed publisher
Lee S, Park Y, Kim K, Cho E, Ahn Y, Kim K, et al. Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell c. Br J Cancer. 2010;103:845-51 pubmed publisher
Shao Y, Kuo K, Hu F, Lu Y, Huang C, Liau J, et al. Predictive and prognostic values of tau and ERCC1 in advanced breast cancer patients treated with paclitaxel and cisplatin. Jpn J Clin Oncol. 2010;40:286-93 pubmed publisher
Bhagwat N, Roginskaya V, Acquafondata M, Dhir R, Wood R, Niedernhofer L. Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue. Cancer Res. 2009;69:6831-8 pubmed publisher
Azim H, Pruneri G, Raviele P, Steffanoni S, Martinelli G, Peccatori F. ERCC1 Expression in Diffuse Large B-Cell Lymphoma Patients Treated with a Cisplatin-Based Regimen : A Brief Communication. J Egypt Natl Canc Inst. 2007;19:176-7 pubmed
Hwang I, Ahn M, Park B, Ahn Y, Han J, Lee S, et al. ERCC1 expression as a prognostic marker in N2(+) nonsmall-cell lung cancer patients treated with platinum-based neoadjuvant concurrent chemoradiotherapy. Cancer. 2008;113:1379-86 pubmed publisher
Jun H, Ahn M, Kim H, Yi S, Han J, Lee S, et al. ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation. Br J Cancer. 2008;99:167-72 pubmed publisher
Kim M, Cho K, Kwon G, Park S, Kim Y, Kim J, et al. Patients with ERCC1-negative locally advanced esophageal cancers may benefit from preoperative chemoradiotherapy. Clin Cancer Res. 2008;14:4225-31 pubmed publisher
Al Minawi A, Saleh Gohari N, Helleday T. The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells. Nucleic Acids Res. 2008;36:1-9 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB500-704
SKU :
NB500-704
product name :
ERCC1 Antibody (8F1) - BSA Free
Description :
The ERCC1 Antibody (8F1) - BSA Free from Novus is a mouse monoclonal antibody to ERCC1. This antibody reacts with human, rat, chinese hamster. The ERCC1 Antibody (8F1) - BSA Free has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin.
target :
ERCC1
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Monoclonal
clone :
8F1
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length recombinant human ERCC1. [UniProt# P07992]
isotype :
IgG2b
purity :
Protein G purified
species :
Human, Rat, Chinese Hamster
gene symbol :
ERCC1
accessionNumbers :
P07992
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin
USD :
399 USD
alt names :
COFS4, DNA excision repair protein ERCC-1, excision repair cross-complementing rodent repair deficiency, complementationgroup 1 (includes overlapping antisense sequence), RAD10, UV20
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.