Survivin Antibody (8E2) | Novus Biologicals NB500-644 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Survivin Antibody (8E2)

catalog :

NB500-644

quantity :

0.1 ml (also 0.025 ml)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8E2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Rosato A, Menin C, Boldrin D, Dalla Santa S, Bonaldi L, Scaini M, et al. Survivin expression impacts prognostically on NSCLC but not SCLC. Lung Cancer. 2013;79:180-6 pubmed publisher
immunocytochemistry; human ELISA; human western blot; human	Fortugno P, Beltrami E, Plescia J, Fontana J, Pradhan D, Marchisio P, et al. Regulation of survivin function by Hsp90. Proc Natl Acad Sci U S A. 2003;100:13791-6 pubmed
immunocytochemistry; human	Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
immunohistochemistry - paraffin section; human flow cytometry; human	Granziero L, Ghia P, Circosta P, Gottardi D, Strola G, Geuna M, et al. Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. Blood. 2001;97:2777-83 pubmed
flow cytometry; human	Grossman D, McNiff J, Li F, Altieri D. Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma. J Invest Dermatol. 1999;113:1076-81 pubmed
immunocytochemistry; human	Li F, Ambrosini G, Chu E, Plescia J, Tognin S, Marchisio P, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature. 1998;396:580-4 pubmed
immunohistochemistry - paraffin section; human	Kawasaki H, Altieri D, Lu C, Toyoda M, Tenjo T, Tanigawa N. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 1998;58:5071-4 pubmed
immunohistochemistry - paraffin section; human ELISA; human western blot; human	Lu C, Altieri D, Tanigawa N. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res. 1998;58:1808-12 pubmed
	Yasuda T, Ura T, Taniguchi M, Yoshida H. Intradermal Delivery of Antigens Enhances Specific IgG and Diminishes IgE Production: Potential Use for Vaccination and Allergy Immunotherapy. PLoS ONE. 2016;11:e0167952 pubmed publisher
	Zeng S, Li Y, Jin Y, Zhang Q, Keller D, McQuaw C, et al. Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis. Mol Cell Biol. 2010;30:935-47 pubmed publisher
	Carvalho A, Carmena M, Sambade C, Earnshaw W, Wheatley S. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci. 2003;116:2987-98 pubmed
	Wheatley S, Carvalho A, Vagnarelli P, Earnshaw W. INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis. Curr Biol. 2001;11:886-90 pubmed
	Kawasaki H, Toyoda M, Shinohara H, Okuda J, Watanabe I, Yamamoto T, et al. Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis. Cancer. 2001;91:2026-32 pubmed
	O Connor D, Grossman D, Plescia J, Li F, Zhang H, Villa A, et al. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci U S A. 2000;97:13103-7 pubmed
	Tanaka K, Iwamoto S, Gon G, Nohara T, Iwamoto M, Tanigawa N. Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res. 2000;6:127-34 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne Brand

catalog number base :

NB500-644

SKU :

NB500-644

product name :

Survivin Antibody (8E2)

Description :

The Survivin Antibody (8E2) from Novus is a mouse monoclonal antibody to Survivin. This antibody reacts with human. The Survivin Antibody (8E2) has been validated for the following applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, In vitro assay, Flow (Intracellular), Block/Neutralize.

target :

Survivin

category :

Primary Antibodies

unit size :

0.1 ml (also 0.025 ml)

buffer :

Tris-Glycine and 0.15M NaCl

clonality :

Monoclonal

clone :

8E2

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This Survivin Antibody (8E2) was developed against full length recombinant human Survivin [UniProt# O15392]

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human

theoretical molecular weight :

16 kDa

gene symbol :

BIRC5

accessionNumbers :

O15392, Q9JHY7

applications :

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, In vitro assay, Flow (Intracellular), Block/Neutralize

USD :

399 USD

alt names :

API4, apoptosis inhibitor 4, Apoptosis inhibitor survivin, baculoviral IAP repeat-containing 5, Baculoviral IAP Repeat-Containing Protein 5, BIRC5, EPR-1, IAP4, survivin variant 3 alpha

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage