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| Lisi L, Pizzoferrato M, Ciotti G, Martire M, Navarra P. mTOR Inhibition Is Effective against Growth, Survival and Migration, but Not against Microglia Activation in Preclinical Glioma Models. Int J Mol Sci. 2023;24: pubmed publisher
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| Qu W, Jeong A, Zhong R, Thieschafer J, Gram A, Li L. Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer's Mice. Mol Neurobiol. 2023;60:495-511 pubmed publisher
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| Jiang C, Zhao X, Jeong T, Kang J, Park J, Kim I, et al. Novel Specific Pyruvate Kinase M2 Inhibitor, Compound 3h, Induces Apoptosis and Autophagy through Suppressing Akt/mTOR Signaling Pathway in LNCaP Cells. Cancers (Basel). 2022;15: pubmed publisher
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| Lee S, Lee J, Park J, Yoon S, Lee K, Kim H. Glycolytic Metabolic Remodeling by the Truncate of Glioma-Associated Oncogene Homolog 1 in Triple-Negative Breast Cancer Cells. J Cancer. 2022;13:3031-3043 pubmed publisher
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| Krunic M, Ristic B, Bosnjak M, Paunovic V, Tovilović Kovačević G, Zogovic N, et al. Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. Free Radic Biol Med. 2021;177:167-180 pubmed publisher
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| Wen X, Zhang J, Yang W, Nie X, Gui R, Shan D, et al. CircRNA-016901 silencing attenuates irradiation-induced injury in bone mesenchymal stem cells via regulating the miR-1249-5p/HIPK2 axis. Exp Ther Med. 2021;21:355 pubmed publisher
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| Li X, Hu Z, Shi H, Wang C, Lei J, Cheng Y. Inhibition of VEGFA Increases the Sensitivity of Ovarian Cancer Cells to Chemotherapy by Suppressing VEGFA-Mediated Autophagy. Onco Targets Ther. 2020;13:8161-8171 pubmed publisher
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| Yefimova M, Lefevre C, Bashamboo A, Eozenou C, Burel A, Lavault M, et al. Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis. Hum Reprod. 2020;35:1346-1362 pubmed publisher
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| Sacitharan P, Bou Gharios G, Edwards J. SIRT1 directly activates autophagy in human chondrocytes. Cell Death Discov. 2020;6:41 pubmed publisher
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| Chen C, Liu L, Shu Y, Jing P, Lu Y, Zhang X, et al. Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons. Neurosci Bull. 2020;36:875-894 pubmed publisher
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| Lee J, Parveen A, Do M, Kang M, Yumnam S, Kim S. Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells. Cell Death Dis. 2020;11:403 pubmed publisher
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| Dutta K, Thammisetty S, Boutej H, Bareil C, Julien J. Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling. J Neurosci. 2020;40:5137-5154 pubmed publisher
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| Zhang R, Li S, Liu L, Yang J, Huang G, Sang Y. TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple. Oncogenesis. 2020;9:45 pubmed publisher
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| Cui D, Drake J, Wilson R, Shute R, Lewellen B, Zhang M, et al. A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway. FASEB J. 2020;34:7330-7344 pubmed publisher
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| Fedele A, Proud C. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling. Biosci Rep. 2020;40: pubmed publisher
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| Zhao J, Li G, Zhao X, Lin X, Gao Y, Raimundo N, et al. Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss. Aging (Albany NY). 2020;12:5590-5611 pubmed publisher
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| Cursano S, Battaglia C, Urrutia Ruiz C, Grabrucker S, Schön M, Bockmann J, et al. A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome. Mol Psychiatry. 2020;: pubmed publisher
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| Urasaki Y, Beaumont C, Workman M, Talbot J, Hill D, Le T. Potency Assessment of CBD Oils by Their Effects on Cell Signaling Pathways. Nutrients. 2020;12: pubmed publisher
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| Odeh M, Tamir Livne Y, Haas T, Bengal E. P38α MAPK coordinates the activities of several metabolic pathways that together induce atrophy of denervated muscles. FEBS J. 2020;287:73-93 pubmed publisher
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| Gao J, Long L, Xu F, Feng L, Liu Y, Shi J, et al. Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischemia/reperfusion injury by inhibiting GSK-3β-mediated activation of autophagy. Br J Pharmacol. 2019;: pubmed publisher
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| Ognibene M, Podesta M, Garaventa A, Pezzolo A. Role of GOLPH3 and TPX2 in Neuroblastoma DNA Damage Response and Cell Resistance to Chemotherapy. Int J Mol Sci. 2019;20: pubmed publisher
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| Sun C, Enkhjargal B, Reis C, Zhang T, Zhu Q, Zhou K, et al. Osteopontin-Enhanced Autophagy Attenuates Early Brain Injury via FAK-ERK Pathway and Improves Long-Term Outcome after Subarachnoid Hemorrhage in Rats. Cells. 2019;8: pubmed publisher
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| Sun C, Enkhjargal B, Reis C, Zhou K, Xie Z, Wu L, et al. Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats. CNS Neurosci Ther. 2019;25:1162-1172 pubmed publisher
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| Tedeschi V, Petrozziello T, Sisalli M, Boscia F, Canzoniero L, Secondo A. The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance. Sci Rep. 2019;9:10743 pubmed publisher
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| Chai W, Ye F, Zeng L, Li Y, Yang L. HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells. J Exp Clin Cancer Res. 2019;38:325 pubmed publisher
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| Roy B, Ahmed I, Ramalingam S, JALA V, Haribabu B, Ramamoorthy P, et al. Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression. Oncotarget. 2019;10:2340-2354 pubmed publisher
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| Tamrakar S, Yashiro M, Kawashima T, Uda T, Terakawa Y, Kuwae Y, et al. Clinicopathological Significance of Autophagy-related Proteins and its Association With Genetic Alterations in Gliomas. Anticancer Res. 2019;39:1233-1242 pubmed publisher
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| Ueno T, Masuda N, Kamigaki S, Morimoto T, Saji S, Imoto S, et al. Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR. Int J Mol Sci. 2019;20: pubmed publisher
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| Ye B, Wang Q, Hu H, Shen Y, Fan C, Chen P, et al. Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR. Autophagy. 2019;15:998-1016 pubmed publisher
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| Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner F, Jendrach M. Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. EMBO J. 2019;38: pubmed publisher
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| Ugun Klusek A, Theodosi T, Fitzgerald J, Burté F, Ufer C, Boocock D, et al. Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation. Redox Biol. 2019;20:167-181 pubmed publisher
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| Zhu Y, Fang J, Wang H, Fei M, Tang T, Liu K, et al. Baicalin suppresses proliferation, migration, and invasion in human glioblastoma cells via Ca2+-dependent pathway. Drug Des Devel Ther. 2018;12:3247-3261 pubmed publisher
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| Sacitharan P, Lwin S, Gharios G, Edwards J. Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300. Exp Mol Med. 2018;50:123 pubmed publisher
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| Dutta K, Patel P, Julien J. Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204 pubmed publisher
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| Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed publisher
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| Ognibene M, Pagnan G, Marimpietri D, Cangelosi D, Cilli M, Benedetti M, et al. CHL1 gene acts as a tumor suppressor in human neuroblastoma. Oncotarget. 2018;9:25903-25921 pubmed publisher
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| Lapierre J, Rodriguez M, Ojha C, El Hage N. Critical Role of Beclin1 in HIV Tat and Morphine-Induced Inflammation and Calcium Release in Glial Cells from Autophagy Deficient Mouse. J Neuroimmune Pharmacol. 2018;13:355-370 pubmed publisher
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| Kivinen N. The role of autophagy in age-related macular degeneration. Acta Ophthalmol. 2018;96 Suppl A110:1-50 pubmed publisher
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| Li Y, Cai W, Wang L, Liu G, Paul C, Jiang L, et al. Identification of the Functional Autophagy-Regulatory Domain in HCLS1-Associated Protein X-1 That Resists Against Oxidative Stress. DNA Cell Biol. 2018;37:432-441 pubmed publisher
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| Lim J, Kim H, Kim M, Kim T, Kim E, Kim Y, et al. Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy. Cell Death Dis. 2018;9:270 pubmed publisher
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| Kim Y, Kwak M, Shin J, Hayuningtyas R, Choi J, Shin J. Inflachromene inhibits autophagy through modulation of Beclin 1 activity. J Cell Sci. 2018;131: pubmed publisher
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| Guo X, Hu F, Wang H, Fang J, Zhu Z, Wei L, et al. Inhibition of autophagy in hepatocarcinoma cells promotes chemotherapeutic agent-induced apoptosis during nutrient deprivation. Oncol Rep. 2017;: pubmed publisher
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| Liu G, Zhu H, Cai W, Wang X, Jiang M, Essandoh K, et al. Regulation of BECN1-Mediated Autophagy by HSPB6: Insights from A Human HSPB6S10F Mutant. Autophagy. 2017;:1-56 pubmed publisher
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| Chang R, Li X, Mu N, Hrydziuszko O, Garcia Majano B, Larsson C, et al. MicroRNA expression profiles in non?epithelial ovarian tumors. Int J Oncol. 2018;52:55-66 pubmed publisher
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| Ouyang Y, Ning S, Adler J, MacIver B, Knox S, Giffard R. Alteration of Interneuron Immunoreactivity and Autophagic Activity in Rat Hippocampus after Single High-Dose Whole-Brain Irradiation. Cureus. 2017;9:e1414 pubmed publisher
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| Li Q, Han Y, Du J, Jin H, Zhang J, Niu M, et al. Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels. Neurosci Res. 2018;130:47-55 pubmed publisher
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| Wang C, Hong Y, Syu J, Tsai Y, Liu X, Chen T, et al. LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells. J Cell Biochem. 2018;119:314-326 pubmed publisher
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| Rodriguez M, Lapierre J, Ojha C, Kaushik A, Batrakova E, Kashanchi F, et al. Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation. Sci Rep. 2017;7:1862 pubmed publisher
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| Zhang L, Wang H, Fan Y, Gao Y, Li X, Hu Z, et al. Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways. Sci Rep. 2017;7:46763 pubmed publisher
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| Gao Y, Zhuang Z, Gao S, Li X, Zhang Z, Ye Z, et al. Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury. Am J Transl Res. 2017;9:887-899 pubmed
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| Gelmetti V, De Rosa P, Torosantucci L, Marini E, Romagnoli A, Di Rienzo M, et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy. 2017;13:654-669 pubmed publisher
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| Syu J, Baba T, Huang J, Ogawa H, Hsieh C, Hu J, et al. Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth. Sci Rep. 2017;7:240 pubmed publisher
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| Huang W, Ao P, Li J, Wu T, Xu L, Deng Z, et al. Autophagy Protects Advanced Glycation End Product-Induced Apoptosis and Expression of MMP-3 and MMP-13 in Rat Chondrocytes. Biomed Res Int. 2017;2017:6341919 pubmed publisher
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| Eritja N, Chen B, Rodríguez Barrueco R, Santacana M, Gatius S, Vidal A, et al. Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer. Autophagy. 2017;13:608-624 pubmed publisher
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| Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
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| Yang Y, Guo C, Liao B, Cao J, Liang C, He X. BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury. Int J Mol Med. 2017;39:423-429 pubmed publisher
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| Jang J, Eom J, Jeung H, Cheong J, Lee J, Kim J, et al. AMPK-ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells. Clin Cancer Res. 2017;23:2781-2794 pubmed publisher
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| Park Y, Park J, Ko J, Shin I, Koh H. mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells. Environ Toxicol. 2017;32:109-121 pubmed publisher
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