Survivin Antibody (60.11) - BSA Free | Novus Biologicals NB500-238 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Survivin Antibody (60.11) - BSA Free

catalog :

NB500-238

quantity :

0.1 ml (also 0.025 ml)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

60.11

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 42

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:500; loading ...; fig 2a western blot; mouse; loading ...; fig 2b	Cho M, Lee O, Chang E, Lee S, Moon S, Lee J, et al. BIRC5 Expression is Regulated in Uterine Epithelium During the Estrous Cycle. Genes (Basel). 2020;11: pubmed publisher
western blot; human	Asuncion Valenzuela M, Castro I, Gonda A, Diaz Osterman C, Jutzy J, Aspe J, et al. Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase. Onco Targets Ther. 2015;8:495-507 pubmed publisher
western blot; human	Khan S, Jutzy J, Valenzuela M, Turay D, Aspe J, Ashok A, et al. Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer. PLoS ONE. 2012;7:e46737 pubmed publisher
western blot; human	Zhang H, Wang Y, Liu C, Zhang L, Xia Q, Zhang Y, et al. DNA and adenovirus tumor vaccine expressing truncated survivin generates specific immune responses and anti-tumor effects in a murine melanoma model. Cancer Immunol Immunother. 2012;61:1857-67 pubmed
immunohistochemistry; human	Lopergolo A, Tavecchio M, Lisanti S, Ghosh J, Dohi T, Faversani A, et al. Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer. Cancer Res. 2012;72:3251-9 pubmed publisher
immunocytochemistry; mouse western blot; mouse	Keerthivasan G, Liu H, Gump J, Dowdy S, Wickrema A, Crispino J. A novel role for survivin in erythroblast enucleation. Haematologica. 2012;97:1471-9 pubmed publisher
immunohistochemistry; mouse western blot; mouse immunohistochemistry; human western blot; human	Sakao K, Desineni S, Hahm E, Singh S. Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo. Prostate. 2012;72:1104-16 pubmed publisher
immunohistochemistry - paraffin section; rat immunohistochemistry; rat	Femia A, Salvianti F, Luceri C, Dolara P, Salvadori M, Pinzani P, et al. Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis. Int J Cancer. 2012;131:529-36 pubmed publisher
immunocytochemistry; human	Lechler P, Balakrishnan S, Schaumburger J, Grassel S, Baier C, Grifka J, et al. The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC Musculoskelet Disord. 2011;12:150 pubmed publisher
immunocytochemistry; human western blot; human	Lechler P, Schaumburger J, Köck F, Balakrishnan S, Doukas S, Prantl L, et al. The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells. Calcif Tissue Int. 2011;89:211-20 pubmed publisher
immunohistochemistry - paraffin section; human immunocytochemistry; human western blot; human	Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, et al. The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer. 2011;11:120 pubmed publisher
immunohistochemistry - paraffin section; mouse western blot; mouse immunohistochemistry - paraffin section; human western blot; human	Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, et al. The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. Am J Pathol. 2007;171:1483-98 pubmed
flow cytometry; human	Koyama S. Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci. 2003;48:2290-300 pubmed
immunohistochemistry - paraffin section; mouse	Allen S, Florell S, Hanks A, Alexander A, Diedrich M, Altieri D, et al. Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. Cancer Res. 2003;63:567-72 pubmed
ELISA; human western blot; human	Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
	Kim S, Shin M, Lee A, Seo B, Park H, Roh S. Improvement of Inflammation through Antioxidant Pathway of Gardeniae Fructus 50% EtOH Extract (GE) from Acute Reflux Esophagitis Rats. Biomed Res Int. 2020;2020:4826176 pubmed publisher
	Ring A, Nguyen C, Smbatyan G, Tripathy D, Yu M, Press M, et al. CBP/β-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel). 2018;10: pubmed publisher
	Fenstermaker R, Figel S, Qiu J, Barone T, Dharma S, Winograd E, et al. Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor Growth In Vivo. Clin Cancer Res. 2018;24:2642-2652 pubmed publisher
	Galbo P, Ciesielski M, Figel S, Maguire O, Qiu J, Wiltsie L, et al. Circulating CD9+/GFAP+/survivin+ exosomes in malignant glioma patients following survivin vaccination. Oncotarget. 2017;8:114722-114735 pubmed publisher
	Gallagher S, Gunatilake D, Beaumont K, Sharp D, Tiffen J, Heinemann A, et al. HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. Int J Cancer. 2018;142:1926-1937 pubmed publisher
	Tsang T, Hsueh Y, Wei E, Lundy D, Cheng B, Chen Y, et al. Subcellular Localization of Survivin Determines Its Function in Cardiomyocytes. Theranostics. 2017;7:4577-4590 pubmed publisher
	Bae I, Kim C, Kim J, Cheong J, Ryu J, Han M. Correlation of survivin and B-cell lymphoma 2 expression with pathological malignancy and anti-apoptotic properties of glial cell tumors. Biomed Rep. 2017;6:396-400 pubmed publisher
	Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed publisher
	Schöneberger H, Weiss A, Brill B, Delis N, Borghouts C, Groner B. The integration of a Stat3 specific peptide aptamer into the thioredoxin scaffold protein strongly enhances its inhibitory potency. Horm Mol Biol Clin Investig. 2011;5:1-9 pubmed publisher
	Kusner L, Ciesielski M, Marx A, Kaminski H, Fenstermaker R. Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. PLoS ONE. 2014;9:e102231 pubmed publisher
	Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed publisher
	Rho J, Lampe P. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. J Proteome Res. 2013;12:2311-20 pubmed publisher
	Hoel A, Yu P, Nguyen K, Sui X, Plescia J, Altieri D, et al. Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo. Am J Pathol. 2012;181:1151-7 pubmed publisher
	de Souza H, West G, Rebert N, de la Motte C, Drazba J, Fiocchi C. Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. Gastroenterology. 2012;143:1017-26.e9 pubmed publisher
	Knauer S, Heinrich U, Bier C, Habtemichael N, Docter D, Helling K, et al. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death Dis. 2010;1:e51 pubmed publisher
	Habtemichael N, W nsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, et al. Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin. Gene. 2010;469:9-17 pubmed publisher
	Habtemichael N, Heinrich U, Knauer S, Schmidtmann I, Bier C, Docter D, et al. Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. Mol Cell Neurosci. 2010;45:297-305 pubmed publisher
	Jiang X, Gwye Y, Russell D, Cao C, Douglas D, Hung L, et al. CD133 expression in chemo-resistant Ewing sarcoma cells. BMC Cancer. 2010;10:116 pubmed publisher
	Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen T, et al. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res. 2008;68:3724-32 pubmed publisher
	Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, et al. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation. 2008;117:1583-93 pubmed publisher
	Hino R, Uozaki H, Inoue Y, Shintani Y, Ushiku T, Sakatani T, et al. Survival advantage of EBV-associated gastric carcinoma: survivin up-regulation by viral latent membrane protein 2A. Cancer Res. 2008;68:1427-35 pubmed publisher
	Brocardo M, Lei Y, Tighe A, Taylor S, Mok M, Henderson B. Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival. J Biol Chem. 2008;283:5950-9 pubmed
	Ryan B, O Donovan N, Browne B, O SHEA C, Crown J, Hill A, et al. Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer. Br J Cancer. 2005;92:120-4 pubmed
	Ansell S, Arendt B, Grote D, Jelinek D, Novak A, Wellik L, et al. Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma. Leukemia. 2004;18:616-23 pubmed
	Ku J, Kwak C, Lee H, Park H, Lee E, Lee S. Expression of survivin, a novel inhibitor of apoptosis, in superficial transitional cell carcinoma of the bladder. J Urol. 2004;171:631-5 pubmed
	Xu Z, Zhao R, Ding T, Tran T, Zhang W, Pandolfi P, et al. Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression. J Biol Chem. 2004;279:1838-44 pubmed
	Zhu L, Fukuda S, Cordis G, Das D, Maulik N. Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. FEBS Lett. 2001;508:369-74 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne Brand

catalog number base :

NB500-238

SKU :

NB500-238

product name :

Survivin Antibody (60.11) - BSA Free

Description :

The Survivin Antibody (60.11) - BSA Free from Novus is a mouse monoclonal antibody to Survivin. This antibody reacts with human, mouse, rat. The Survivin Antibody (60.11) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Proximity Ligation Assay, Flow (Intracellular), Knockdown Validated.

target :

Survivin

category :

Primary Antibodies

unit size :

0.1 ml (also 0.025 ml)

buffer :

PBS

clonality :

Monoclonal

clone :

60.11

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This Survivin Antibody (60.11) [Alexa Fluor 350] was developed against full length recombinant human Survivin [UniProt# O15392]

isotype :

IgG2a Kappa

purity :

Protein G purified

species :

Human, Mouse, Rat

specificity :

Survivin Antibody (60

theoretical molecular weight :

16 kDa

gene symbol :

BIRC5

applications :

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Proximity Ligation Assay, Flow (Intracellular), Knockdown Validated

USD :

399 USD

alt names :

API4, apoptosis inhibitor 4, Apoptosis inhibitor survivin, baculoviral IAP repeat-containing 5, Baculoviral IAP Repeat-Containing Protein 5, BIRC5, EPR-1, IAP4, survivin variant 3 alpha

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage