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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Survivin Antibody (32.1) - BSA Free
catalog :
NB500-237
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32.1
reactivity :
hamsters, human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; hamsters
  • western blot; human
Hori M, Miki T, Okamoto M, Yazama F, Konishi H, Kaneko H, et al. The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer. PLoS ONE. 2013;8:e55710 pubmed publisher
  • immunoprecipitation; human
Güvenç H, Pavlyukov M, Joshi K, Kurt H, Banasavadi Siddegowda Y, Mao P, et al. Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex. Clin Cancer Res. 2013;19:631-42 pubmed publisher
  • immunocytochemistry; human
Lechler P, Schaumburger J, Köck F, Balakrishnan S, Doukas S, Prantl L, et al. The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells. Calcif Tissue Int. 2011;89:211-20 pubmed publisher
  • immunohistochemistry; human
  • western blot; human
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, et al. Intracellular localization of survivin determines biological behavior in colorectal cancer. Oncol Rep. 2009;22:557-62 pubmed
  • immunohistochemistry - paraffin section; human
Ding Y, Prieto V, Zhang P, Rosenthal S, Smith K, Skelton H, et al. Nuclear expression of the antiapoptotic protein survivin in malignant melanoma. Cancer. 2006;106:1123-9 pubmed
  • immunoprecipitation; human
  • immunocytochemistry; human
  • ELISA; human
  • western blot; human
Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
Jiang Y, Wan Y, Gong M, Zhou S, Qiu J, Cheng W. RNA demethylase ALKBH5 promotes ovarian carcinogenesis in a simulated tumour microenvironment through stimulating NF-κB pathway. J Cell Mol Med. 2020;24:6137-6148 pubmed publisher
Li X, Jin F, Wang B, Yin X, Hong W, Tian F. The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA. Theranostics. 2019;9:3853-3865 pubmed publisher
Wu X, Li Y, Liu X, Chen C, Harrington S, Cao S, et al. Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy. Heliyon. 2018;4:e01039 pubmed publisher
Meunier M, Scandolera A, Chapuis E, Lambert C, Jarrin C, Robe P, et al. From stem cells protection to skin microbiota balance: Orobanche rapum extract, a new natural strategy. J Cosmet Dermatol. 2019;18:1140-1154 pubmed publisher
Zhang C, Zhi W, Lu H, Samanta D, Chen I, Gabrielson E, et al. Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells. Oncotarget. 2016;7:64527-64542 pubmed publisher
Zhang C, Samanta D, Lu H, Bullen J, Zhang H, Chen I, et al. Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m?A-demethylation of NANOG mRNA. Proc Natl Acad Sci U S A. 2016;113:E2047-56 pubmed publisher
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, et al. The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer. 2011;11:120 pubmed publisher
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, et al. The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. Am J Pathol. 2007;171:1483-98 pubmed
Giodini A, Kallio M, Wall N, Gorbsky G, Tognin S, Marchisio P, et al. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res. 2002;62:2462-7 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB500-237
SKU :
NB500-237
product name :
Survivin Antibody (32.1) - BSA Free
Description :
The Survivin Antibody (32.1) - BSA Free from Novus is a mouse monoclonal antibody to Survivin. This antibody reacts with human, hamster. The Survivin Antibody (32.1) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.
target :
Survivin
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Monoclonal
clone :
32.1
concentration :
1.9 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This Survivin Antibody (32.1) was developed against full length recombinant human Survivin [UniProt# O15392]
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human, Hamster
specificity :
Survivin Antibody (32
theoretical molecular weight :
16 kDa
gene symbol :
BIRC5
applications :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin
USD :
399 USD
alt names :
API4, apoptosis inhibitor 4, Apoptosis inhibitor survivin, baculoviral IAP repeat-containing 5, Baculoviral IAP Repeat-Containing Protein 5, BIRC5, EPR-1, IAP4, survivin variant 3 alpha
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.