SMAC/Diablo Antibody (78-1-118) | Novus Biologicals NB500-213 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

SMAC/Diablo Antibody (78-1-118)

catalog :

NB500-213

quantity :

0.2 ml (also 0.05 ml)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

78-1-118

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 1	Hwang H, Dornbos P, Steidemann M, Dunivin T, Rizzo M, LaPres J. Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome. Toxicol Appl Pharmacol. 2016;304:121-32 pubmed publisher
western blot; mouse	Zhang Y, Cook A, Kim J, Baranov S, Jiang J, Smith K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiol Dis. 2013;55:26-35 pubmed publisher
western blot; mouse western blot; rat	Wang X, Zhu S, Pei Z, Drozda M, Stavrovskaya I, Del Signore S, et al. Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease. J Neurosci. 2008;28:9473-85 pubmed publisher
western blot; mouse	Zhang W, Wang X, Narayanan M, Zhang Y, Huo C, Reed J, et al. Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proc Natl Acad Sci U S A. 2003;100:16012-7 pubmed
immunocytochemistry; rat western blot; rat immunocytochemistry; mouse western blot; mouse	Wang X, Zhu S, Drozda M, Zhang W, Stavrovskaya I, Cattaneo E, et al. Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease. Proc Natl Acad Sci U S A. 2003;100:10483-7 pubmed
	Taveau N, Cubizolle A, Guillou L, Pinquier N, Moine E, Cia D, et al. Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy. Exp Mol Med. 2020;52:1090-1101 pubmed publisher
	Mäkeläinen S, Gòdia M, Hellsand M, Viluma A, Hahn D, Makdoumi K, et al. An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease. PLoS Genet. 2019;15:e1007873 pubmed publisher
	Sirianni A, Jiang J, Zeng J, Mao L, Zhou S, Sugarbaker P, et al. N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis. J Neurochem. 2015;134:956-68 pubmed publisher
	Wang X, Sirianni A, Pei Z, Cormier K, Smith K, Jiang J, et al. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity. J Neurosci. 2011;31:14496-507 pubmed publisher
	Zhang Y, Wang X, Baranov S, Zhu S, Huang Z, Fellows Mayle W, et al. Dipyrone inhibits neuronal cell death and diminishes hypoxic/ischemic brain injury. Neurosurgery. 2011;69:942-56 pubmed publisher
	Zhang W, Wang H, Wang X, Narayanan M, Stavrovskaya I, Kristal B, et al. Nortriptyline protects mitochondria and reduces cerebral ischemia/hypoxia injury. Stroke. 2008;39:455-62 pubmed publisher
	Liu J, Deng T, Lehal R, Kim J, Zacksenhaus E. Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors. Cancer Res. 2007;67:8671-81 pubmed
	Wiszniewski W, Zaremba C, Yatsenko A, Jamrich M, Wensel T, Lewis R, et al. ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies. Hum Mol Genet. 2005;14:2769-78 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne Brand

catalog number base :

NB500-213

SKU :

NB500-213

product name :

SMAC/Diablo Antibody (78-1-118)

Description :

The SMAC/Diablo Antibody (78-1-118) from Novus is a mouse monoclonal antibody to SMAC/Diablo. This antibody reacts with human, mouse, rat. The SMAC/Diablo Antibody (78-1-118) has been validated for the following applications: Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation.

target :

SMAC/Diablo

category :

Primary Antibodies

unit size :

0.2 ml (also 0.05 ml)

buffer :

Ascites

clonality :

Monoclonal

clone :

78-1-118

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant mature human Smac (lacks amino acids 1-55 present in Smac precursor). [UniProt# Q9NR28]

isotype :

IgG3/IgG1

purity :

Unpurified

species :

Human, Mouse, Rat

theoretical molecular weight :

25 kDa

gene symbol :

DIABLO

accessionNumbers :

Q9NR28

applications :

Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

USD :

399 USD

alt names :

0610041G12Rik, diablo, IAP-binding mitochondrial protein, Direct IAP-binding protein with low pI, mitochondrial Smac protein, Second mitochondria-derived activator of caspase, Smac, SMACmitochondrial

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage