Survivin Antibody (60.11) - Unpurified | Novus Biologicals NB500-205 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Survivin Antibody (60.11) - Unpurified

catalog :

NB500-205

quantity :

0.1 ml (also 0.025 ml)

price :

349 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

60.11

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 23

Reference
Breder Bonk C, Docter D, Barz M, Strieth S, Knauer S, G xfc l D, et al. The Apoptosis Inhibitor Protein Survivin Is a Critical Cytoprotective Resistor against Silica-Based Nanotoxicity. Nanomaterials (Basel). 2023;13: pubmed publisher
Kim S, Shin M, Lee A, Seo B, Park H, Roh S. Improvement of Inflammation through Antioxidant Pathway of Gardeniae Fructus 50% EtOH Extract (GE) from Acute Reflux Esophagitis Rats. Biomed Res Int. 2020;2020:4826176 pubmed publisher
Ring A, Nguyen C, Smbatyan G, Tripathy D, Yu M, Press M, et al. CBP/β-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel). 2018;10: pubmed publisher
Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed publisher
Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed publisher
Hoel A, Yu P, Nguyen K, Sui X, Plescia J, Altieri D, et al. Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo. Am J Pathol. 2012;181:1151-7 pubmed publisher
de Souza H, West G, Rebert N, de la Motte C, Drazba J, Fiocchi C. Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. Gastroenterology. 2012;143:1017-26.e9 pubmed publisher
Lechler P, Balakrishnan S, Schaumburger J, Grassel S, Baier C, Grifka J, et al. The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC Musculoskelet Disord. 2011;12:150 pubmed publisher
Knauer S, Heinrich U, Bier C, Habtemichael N, Docter D, Helling K, et al. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death Dis. 2010;1:e51 pubmed publisher
Habtemichael N, W nsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, et al. Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin. Gene. 2010;469:9-17 pubmed publisher
Habtemichael N, Heinrich U, Knauer S, Schmidtmann I, Bier C, Docter D, et al. Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. Mol Cell Neurosci. 2010;45:297-305 pubmed publisher
Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen T, et al. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res. 2008;68:3724-32 pubmed publisher
Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, et al. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation. 2008;117:1583-93 pubmed publisher
Hino R, Uozaki H, Inoue Y, Shintani Y, Ushiku T, Sakatani T, et al. Survival advantage of EBV-associated gastric carcinoma: survivin up-regulation by viral latent membrane protein 2A. Cancer Res. 2008;68:1427-35 pubmed publisher
Brocardo M, Lei Y, Tighe A, Taylor S, Mok M, Henderson B. Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival. J Biol Chem. 2008;283:5950-9 pubmed
Ryan B, O Donovan N, Browne B, O SHEA C, Crown J, Hill A, et al. Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer. Br J Cancer. 2005;92:120-4 pubmed
Ansell S, Arendt B, Grote D, Jelinek D, Novak A, Wellik L, et al. Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma. Leukemia. 2004;18:616-23 pubmed
Koyama S. Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci. 2003;48:2290-300 pubmed
Ku J, Kwak C, Lee H, Park H, Lee E, Lee S. Expression of survivin, a novel inhibitor of apoptosis, in superficial transitional cell carcinoma of the bladder. J Urol. 2004;171:631-5 pubmed
Xu Z, Zhao R, Ding T, Tran T, Zhang W, Pandolfi P, et al. Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression. J Biol Chem. 2004;279:1838-44 pubmed
Allen S, Florell S, Hanks A, Alexander A, Diedrich M, Altieri D, et al. Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. Cancer Res. 2003;63:567-72 pubmed
Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
Zhu L, Fukuda S, Cordis G, Das D, Maulik N. Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. FEBS Lett. 2001;508:369-74 pubmed

image

image 1 :

Western Blot: Survivin Antibody (60.11) - Unpurified [NB500-205] - Survivin detected in rat aorta smooth muscle cell lysate in western blot analysis using [NB500-205]. Theoretical molecular weight: 16 kDa.

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB500-205

SKU :

NB500-205

product name :

Survivin Antibody (60.11) - Unpurified

description :

The Survivin Antibody (60.11) - Unpurified from Novus Biologicals is a mouse monoclonal antibody to Survivin. This antibody reacts with human,mouse,rat. The Survivin Antibody (60.11) - Unpurified has been validated for the following applications: Flow Cytometry,ELISA,Immunoprecipitation,Knockdown Validated,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence.

target :

Survivin

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

Ascites with PBS

clonality :

Monoclonal

clone :

60.11

conjugate :

Unconjugated

host :

Mouse

immunogen :

This Survivin Antibody (60.11) was developed against full length recombinant human Survivin [UniProt# O15392].

isotype :

IgG2a Kappa

purity :

Unpurified

species :

Human,Mouse,Rat

specificity :

Survivin Antibody (60

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

theoretical molecular weight :

16 kDa

gene symbol :

BIRC5

accessionNumbers :

O15392

applications :

Flow Cytometry,ELISA,Immunoprecipitation,Knockdown Validated,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence

USD :

339

USD 2025 :

349 USD

alt names :

API4, apoptosis inhibitor 4, Apoptosis inhibitor survivin, baculoviral IAP repeat-containing 5, Baculoviral IAP Repeat-Containing Protein 5, BIRC5, EPR-1, IAP4, survivin variant 3 alpha

more info or order :

Novus Biologicals product webpage