product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Survivin Antibody - BSA Free
catalog :
NB500-201
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
AF488
clone name :
OTI2B3
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 111
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 4b
Kreger B, Johansen E, Cerione R, Antonyak M. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers (Basel). 2016;8: pubmed
  • western blot; human; loading ...; fig 1c
Schafer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, et al. Class I histone deacetylases regulate p53/NF-?B crosstalk in cancer cells. Cell Signal. 2017;29:218-225 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 3
Unruhe Knauf B, Knauer S. Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. Methods Mol Biol. 2017;1510:47-59 pubmed
  • western blot; human; 1:1000; fig 3
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher
Stahl P, Kollenda S, Sager J, Schmidt L, Schroer M, Stauber R, et al. Tuning Nanobodies' Bioactivity: Coupling to Ultrasmall Gold Nanoparticles Allows the Intracellular Interference with Survivin. Small. 2023;19:e2300871 pubmed publisher
Dyshlovoy S, Shubina L, Makarieva T, Guzii A, Hauschild J, Strewinsky N, et al. New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge Monanchora pulchra Induce Apoptosis and Autophagy in Prostate Cancer Cells. Mar Drugs. 2022;20: pubmed publisher
Vay C, Babaei S, Safi S, Dizdar L, Rehders A, Haeberle L, et al. Clinicopathological and Prognostic Value of Survivin Expression in Surgically Resected Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2022;14: pubmed publisher
da Costa Lopes J, Falc xe3 o L, Martins Filho A, Carvalho M, Mendes C, Ol xed mpio F, et al. Factors Involved in the Apoptotic Cell Death Mechanism in Yellow Fever Hepatitis. Viruses. 2022;14: pubmed publisher
Mackay R, Weinberger P, Copland J, Mahdavian E, Xu Q. YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site. Mol Cancer Ther. 2022;21:925-935 pubmed publisher
Rodrigues de Sousa J, Magno Falc xe3 o L, Virgolino G, Santos Cruz M, Teixeira V, Leila de Souza Aar xe3 o T, et al. Different cell death mechanisms are involved in leprosy pathogenesis. Microb Pathog. 2022;166:105511 pubmed publisher
Almeida A, Soares de Oliveira J, Drpic D, Cheeseman L, Damas J, Lewin H, et al. Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals. Cell Rep. 2022;39:110610 pubmed publisher
Vay C, Schlünder P, Dizdar L, Esposito I, Ghadimi M, Knoefel W, et al. Targeting abundant survivin expression in liposarcoma: subtype dependent therapy responses to YM155 treatment. J Cancer Res Clin Oncol. 2022;148:633-645 pubmed publisher
Arista Romero M, Cascante A, Fornaguera C, Borros S. Role of Survivin in Bladder Cancer: Issues to Be Overcome When Designing an Efficient Dual Nano-Therapy. Pharmaceutics. 2021;13: pubmed publisher
Di Vincenzo S, Sangiorgi C, Ferraro M, Buscetta M, Cipollina C, Pace E. Cigarette smoke extract reduces FOXO3a promoting tumor progression and cell migration in lung cancer. Toxicology. 2021;454:152751 pubmed publisher
Oliveira A, Zerillo L, Cruz L, Schomann T, Chan A, de Carvalho T, et al. Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer. Mater Sci Eng C Mater Biol Appl. 2021;120:111678 pubmed publisher
Ferguson Bennit H, Gonda A, Kabagwira J, Oppegard L, Chi D, Licero Campbell J, et al. Natural Killer Cell Phenotype and Functionality Affected by Exposure to Extracellular Survivin and Lymphoma-Derived Exosomes. Int J Mol Sci. 2021;22: pubmed publisher
Abdo W, Elmadawy M, Abdelhiee E, Abdel Kareem M, Farag A, Aboubakr M, et al. Protective effect of thymoquinone against lung intoxication induced by malathion inhalation. Sci Rep. 2021;11:2498 pubmed publisher
Murillo Pineda M, Valente L, Dumont M, Mata J, Fachinetti D, Jansen L. Induction of spontaneous human neocentromere formation and long-term maturation. J Cell Biol. 2021;220: pubmed publisher
Tsunematsu T, Arakaki R, Kawai H, Ruppert J, Tsuneyama K, Ishimaru N, et al. APC/CCdh1 is required for the termination of chromosomal passenger complex activity upon mitotic exit. J Cell Sci. 2020;133: pubmed publisher
Nourreddine S, Lavoie G, Paradis J, Ben El Kadhi K, Méant A, Aubert L, et al. NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay. Cell Rep. 2020;31:107660 pubmed publisher
Dyshlovoy S, Pelageev D, Hauschild J, Sabutskii Y, Khmelevskaya E, Krisp C, et al. Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer. Mar Drugs. 2020;18: pubmed publisher
Erdogan S, Türkekul K. Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation. J Food Biochem. 2020;44:e13253 pubmed publisher
Thamm D, Joseph J, Rose B, Meuten T, Weishaar K. Phase-I trial of survivin inhibition with EZN-3042 in dogs with spontaneous lymphoma. BMC Vet Res. 2020;16:97 pubmed publisher
Brown M, Zhang W, Yan D, Kenath R, Le L, Wang H, et al. The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC. PLoS ONE. 2020;15:e0226917 pubmed publisher
Liang C, Zhang Z, Chen Q, Yan H, Zhang M, Zhou L, et al. Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation. J Cell Biol. 2020;219: pubmed publisher
Mirshahidi S, De Necochea Campion R, Moretta A, Williams N, Reeves M, Otoukesh S, et al. Inhibitory Effects of Indomethacin in Human MNNG/HOS Osteosarcoma Cell Line In Vitro. Cancer Invest. 2020;38:23-36 pubmed publisher
Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, et al. Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma. Mol Cancer. 2019;18:159 pubmed publisher
Abad M, Ruppert J, Buzuk L, Wear M, Zou J, Webb K, et al. Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex. J Cell Biol. 2019;218:3912-3925 pubmed publisher
Ong S, Saeki K, Kok M, Nakagawa T, Nishimura R. YM155 enhances the cytotoxic activity of etoposide against canine osteosarcoma cells. J Vet Med Sci. 2019;81:1182-1190 pubmed publisher
Kubo T, Tsurita G, Hirohashi Y, Yasui H, Ota Y, Watanabe K, et al. Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series. Cancer Sci. 2019;110:2386-2395 pubmed publisher
Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, et al. Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Dev Cell. 2019;49:393-408.e7 pubmed publisher
Zuckerman L, Frames W, Elsissy J, Shields T, De Necochea Campion R, Mirshahidi H, et al. The effect of non-steroidal anti-inflammatory drugs on osteosarcoma cells. Eur Rev Med Pharmacol Sci. 2019;23:2681-2690 pubmed publisher
Zito P, Labbozzetta M, Notarbartolo M, Sajeva M, Poma P. Essential oil of Cyphostemma juttae (Vitaceae): Chemical composition and antitumor mechanism in triple negative breast cancer cells. PLoS ONE. 2019;14:e0214594 pubmed publisher
Ketteler J, Panic A, Reis H, Wittka A, Maier P, Herskind C, et al. Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1. J Clin Med. 2019;8: pubmed publisher
Lionetti M, Mutti F, Soldati E, Fumagalli M, Coccè V, Colombo G, et al. Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide. Int J Environ Res Public Health. 2019;16: pubmed publisher
Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O. Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019;692:217-222 pubmed publisher
Liu T, Liu J, Chen Q, Jin S, Mi S, Shao W, et al. Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma. Oncol Lett. 2019;17:2040-2046 pubmed publisher
Ferraro M, Di Vincenzo S, Dino P, Bucchieri S, Cipollina C, Gjomarkaj M, et al. Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. Exp Gerontol. 2019;118:78-87 pubmed publisher
Kim W, Ryu J, Kim J. CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells. Int J Mol Sci. 2019;20: pubmed publisher
Hwang J, Park J, Kim M, Kim W, Ha K, Choi B, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model. Cancer Lett. 2018;443:25-33 pubmed publisher
Gonda A, Kabagwira J, Senthil G, Ferguson Bennit H, Neidigh J, Khan S, et al. Exosomal survivin facilitates vesicle internalization. Oncotarget. 2018;9:34919-34934 pubmed publisher
Giuliani A, Cirilli I, Prattichizzo F, Mensà E, Fulgenzi G, Sabbatinelli J, et al. The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells. Aging (Albany NY). 2018;10:2855-2873 pubmed publisher
Humphry N, Wheatley S. Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3. Biol Open. 2018;7: pubmed publisher
Wang T, Huang J, Vue M, Alavian M, Goel H, Altieri D, et al. αvβ3 Integrin Mediates Radioresistance of Prostate Cancer Cells through Regulation of Survivin. Mol Cancer Res. 2019;17:398-408 pubmed publisher
Troiano G, Guida A, Aquino G, Botti G, Losito N, Papagerakis S, et al. Integrative Histologic and Bioinformatics Analysis of BIRC5/Survivin Expression in Oral Squamous Cell Carcinoma. Int J Mol Sci. 2018;19: pubmed publisher
Gock M, Mullins C, Harnack C, Prall F, Ramer R, Göder A, et al. Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line. World J Gastroenterol. 2018;24:3749-3759 pubmed publisher
Lee H, Carmena M, Liskovykh M, Peat E, Kim J, Oshimura M, et al. Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy. Cancer Res. 2018;78:6282-6296 pubmed publisher
Erdogan S, Türkekul K, Dibirdik I, Doganlar O, Doganlar Z, Bilir A, et al. Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway. Biomed Pharmacother. 2018;107:793-805 pubmed publisher
Novais Cruz M, Alba Abad M, van IJcken W, Galjart N, Jeyaprakash A, Maiato H, et al. Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription. elife. 2018;7: pubmed publisher
Rauch A, Carlstedt A, Emmerich C, Mustafa A, Göder A, Knauer S, et al. Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells. Oncotarget. 2018;9:27835-27850 pubmed publisher
Kiweler N, Brill B, Wirth M, Breuksch I, Laguna T, Dietrich C, et al. The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells. Arch Toxicol. 2018;92:2227-2243 pubmed publisher
Drpic D, Almeida A, Aguiar P, Renda F, Damas J, Lewin H, et al. Chromosome Segregation Is Biased by Kinetochore Size. Curr Biol. 2018;28:1344-1356.e5 pubmed publisher
Dizdar L, Jünemann L, Werner T, Verde P, Baldus S, Stoecklein N, et al. Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer. Oncol Lett. 2018;15:3779-3789 pubmed publisher
Wei Q, Li J, Tang F, Yin Y, Zhao Y, Yao Q. Synthesis and biological evaluation of novel 2-arylvinyl-substituted naphtho[2,3-d]imidazolium halide derivatives as potent antitumor agents. Eur J Med Chem. 2018;144:504-516 pubmed publisher
Tastekin E, Caloglu V, Durankus N, Sut N, Turkkan G, Can N, et al. Survivin expression, HPV positivity and microvessel density in oropharyngeal carcinomas and relationship with survival time. Arch Med Sci. 2017;13:1467-1473 pubmed publisher
Liang C, Chen Q, Yi Q, Zhang M, Yan H, Zhang B, et al. A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion. EMBO Rep. 2018;19:43-56 pubmed publisher
Dizdar L, Tomczak M, Werner T, Safi S, Riemer J, Verde P, et al. Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas. Oncol Lett. 2017;14:6847-6856 pubmed publisher
Zhang J, Jin Y, Pan J. Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR?ABL?positive CML cells. Mol Med Rep. 2017;16:9217-9223 pubmed publisher
Khan S, Simpson J, Lynch J, Turay D, Mirshahidi S, Gonda A, et al. Racial differences in the expression of inhibitors of apoptosis (IAP) proteins in extracellular vesicles (EV) from prostate cancer patients. PLoS ONE. 2017;12:e0183122 pubmed publisher
Taglieri L, Rubinacci G, Giuffrida A, Carradori S, Scarpa S. The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells. Invest New Drugs. 2018;36:28-35 pubmed publisher
Ong S, Saeki K, Kok M, Tanaka Y, Choisunirachon N, Yoshitake R, et al. Anti-tumour efficacy of etoposide alone and in combination with piroxicam against canine osteosarcoma in a xenograft model. Res Vet Sci. 2017;113:130-135 pubmed publisher
Taglieri L, DE Iuliis F, Giuffrida A, Giantulli S, Silvestri I, Scarpa S. Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells. Oncol Lett. 2017;14:3832-3838 pubmed publisher
Werner T, Dizdar L, Nolten I, Riemer J, Mersch S, Schütte S, et al. Survivin and XIAP - two potential biological targets in follicular thyroid carcinoma. Sci Rep. 2017;7:11383 pubmed publisher
Craparo E, Ferraro M, Pace E, Bondi M, Giammona G, Cavallaro G. Polyaspartamide-Based Nanoparticles Loaded with Fluticasone Propionate and the In Vitro Evaluation towards Cigarette Smoke Effects. Nanomaterials (Basel). 2017;7: pubmed publisher
Bradford E, Ryu S, Singh A, Lee G, Goretsky T, Sinh P, et al. Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease. J Immunol. 2017;199:1886-1897 pubmed publisher
Wang H, Jin S, Lu H, Mi S, Shao W, Zuo X, et al. Expression of survivin, MUC2 and MUC5 in colorectal cancer and their association with clinicopathological characteristics. Oncol Lett. 2017;14:1011-1016 pubmed publisher
Magadum A, Ding Y, He L, Kim T, Vasudevarao M, Long Q, et al. Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair. Cell Res. 2017;27:1002-1019 pubmed publisher
Scheer A, Knauer S, Verhaegh R. Survivin expression pattern in the intestine of normoxic and ischemic rats. BMC Gastroenterol. 2017;17:76 pubmed publisher
Tung J, Tew L, Hsu Y, Khung Y. A novel 4-arm DNA/RNA Nanoconstruct triggering Rapid Apoptosis of Triple Negative Breast Cancer Cells within 24?hours. Sci Rep. 2017;7:793 pubmed publisher
Liu S, Shi L, Yang X, Ye D, Wang T, Dong C, et al. Nuclear survivin promoted by acetylation is associated with the aggressive phenotype of oral squamous cell carcinoma. Cell Cycle. 2017;16:894-902 pubmed publisher
Chen B, Wei W, Ma L, Yang B, Gill R, Chua M, et al. Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. Gastroenterology. 2017;152:2022-2036 pubmed publisher
Kim W, Cheon M, Kim J. Mitochondrial CCAR2/DBC1 is required for cell survival against rotenone-induced mitochondrial stress. Biochem Biophys Res Commun. 2017;485:782-789 pubmed publisher
Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed publisher
Nonagase Y, Yonesaka K, Kawakami H, Watanabe S, Haratani K, Takahama T, et al. Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1. Oncotarget. 2016;7:84860-84871 pubmed publisher
Redli P, Gasic I, Meraldi P, Nigg E, Santamaria A. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. J Cell Biol. 2016;215:77-93 pubmed
Lettini G, Sisinni L, Condelli V, Matassa D, Simeon V, Maddalena F, et al. TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma. Cell Death Differ. 2016;23:1792-1803 pubmed publisher
Makii C, Oda K, Ikeda Y, Sone K, Hasegawa K, Uehara Y, et al. MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53. Oncotarget. 2016;7:75328-75338 pubmed publisher
Genshaft A, Li S, Gallant C, Darmanis S, Prakadan S, Ziegler C, et al. Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biol. 2016;17:188 pubmed publisher
Varughese R, Torp S. Survivin and gliomas: A literature review. Oncol Lett. 2016;12:1679-1686 pubmed
Tastekin E, Caloglu V, Puyan F, Tokuc B, Caloglu M, Yalta T, et al. Prognostic Value of Angiogenesis and Survivin Expression in Patients with Glioblastoma. Turk Neurosurg. 2016;26:484-90 pubmed publisher
Alzoubi S, Brody L, Rahman S, Mahul Mellier A, Mercado N, Ito K, et al. Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget. 2016;7:44505-44521 pubmed publisher
Pace E, Di Vincenzo S, Ferraro M, Bruno A, Dino P, Bonsignore M, et al. Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells. Exp Gerontol. 2016;81:119-28 pubmed publisher
Qi G, Kudo Y, Tang B, Liu T, Jin S, Liu J, et al. PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer. Oncotarget. 2016;7:18812-24 pubmed publisher
Wu X, Tang W, Marquez R, Li K, Highfill C, He F, et al. Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling. Oncotarget. 2016;7:11708-23 pubmed publisher
Werner T, Tamkan Ölcek Y, Dizdar L, Riemer J, Wolf A, Cupisti K, et al. Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma. Br J Cancer. 2016;114:427-34 pubmed publisher
Lotti R, Palazzo E, Petrachi T, Dallaglio K, Saltari A, Truzzi F, et al. Survivin Modulates Squamous Cell Carcinoma-Derived Stem-Like Cell Proliferation, Viability and Tumor Formation in Vivo. Int J Mol Sci. 2016;17: pubmed publisher
Christenson J, Denny E, Kane S. t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib. Oncotarget. 2015;6:33134-45 pubmed publisher
Fukuda T, Wada Hiraike O, Oda K, Tanikawa M, Makii C, Inaba K, et al. Putative tumor suppression function of SIRT6 in endometrial cancer. FEBS Lett. 2015;589:2274-81 pubmed publisher
Labarrade F, Bergeron L, Serre C, Lebleu A, Busuttil V, Botto J, et al. Modulating the expression of survivin and other basal epidermal proteins protects human skin from UVB damage and oxidative stress. J Cosmet Dermatol. 2015;14:191-203 pubmed publisher
Papini D, Langemeyer L, Abad M, Kerr A, Samejima I, Eyers P, et al. TD-60 links RalA GTPase function to the CPC in mitosis. Nat Commun. 2015;6:7678 pubmed publisher
Yamazaki H, Takagi S, Hosoya K, Okumura M. Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells. Vet J. 2015;205:375-80 pubmed publisher
Locke F, Menges M, Veerapathran A, Coppola D, Gabrilovich D, Anasetti C. Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma. J Immunother Cancer. 2015;3:20 pubmed publisher
Valenzuela M, Ferguson Bennit H, Gonda A, Diaz Osterman C, Hibma A, Khan S, et al. Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP). Cancer Microenviron. 2015;8:65-73 pubmed publisher
Bongiovanni L, D Andrea A, Porcellato I, Ciccarelli A, Malatesta D, Romanucci M, et al. Canine cutaneous melanocytic tumours: significance of β-catenin and survivin immunohistochemical expression. Vet Dermatol. 2015;26:270-e59 pubmed publisher
Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
Mehta A, Zhang L, Boufraqech M, Liu Chittenden Y, Zhang Y, Patel D, et al. Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer. Clin Cancer Res. 2015;21:4123-32 pubmed publisher
Zhang L, Zhang Y, Mehta A, Boufraqech M, Davis S, Wang J, et al. Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer. Oncotarget. 2015;6:9073-85 pubmed
Lan L, Appelman C, Smith A, Yu J, Larsen S, Marquez R, et al. Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol Oncol. 2015;9:1406-20 pubmed publisher
Sulaiman M, Chu Z, Blanco V, Vallabhapurapu S, Franco R, Qi X. SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas. Mol Cancer. 2015;14:78 pubmed publisher
Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed publisher
Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed publisher
Yamazaki H, Takagi S, Hosoya K, Okumura M. Survivin suppressor (YM155) enhances chemotherapeutic efficacy against canine histiocytic sarcoma in murine transplantation models. Res Vet Sci. 2015;99:137-44 pubmed publisher
Wu X, Yamamoto H, Nakanishi H, Yamamoto Y, Inoue A, Tei M, et al. Innovative delivery of siRNA to solid tumors by super carbonate apatite. PLoS ONE. 2015;10:e0116022 pubmed publisher
Yi X, Han T, Li Y, Long X, Li W. Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway. Mol Med Rep. 2015;12:601-8 pubmed publisher
Lu H, Cao X, Chen Q, Chen L, Chen L, Gan M. The expression and role of MEKK3 in renal clear cell carcinoma. Anat Rec (Hoboken). 2015;298:727-34 pubmed publisher
Vogt N, Abramov D, Koch K, Masque Soler N, Szczepanowski M, Klapper W. No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo. Leuk Lymphoma. 2015;56:2134-40 pubmed publisher
Artesi M, Kroonen J, Bredel M, Nguyen Khac M, Deprez M, Schoysman L, et al. Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy. Neuro Oncol. 2015;17:392-406 pubmed publisher
Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int J Cancer. 2015;136:1308-20 pubmed publisher
Ramírez Labrada A, López Royuela N, Jarauta V, Galán Malo P, Azaceta G, Palomera L, et al. Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis. Clin Transl Oncol. 2015;17:121-32 pubmed publisher
Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed publisher
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg E, Mayer T, et al. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol. 2003;162:863-75 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB500-201
SKU :
NB500-201
product name :
Survivin Antibody - BSA Free
Description :
The Survivin Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Survivin. This antibody reacts with human, mouse, rat, canine, feline, guinea pig, hamster. The Survivin Antibody - BSA Free has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Chromatin Immunoprecipitation (ChIP), Knockdown Validated, Dual RNAscope ISH-IHC.
target :
Survivin
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This Survivin Antibody was developed against full length recombinant human Survivin [UniProt# O15392]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat, Canine, Feline, Guinea Pig, Hamster
theoretical molecular weight :
16 kDa
gene symbol :
BIRC5
accessionNumbers :
O15392
applications :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Chromatin Immunoprecipitation (ChIP), Knockdown Validated, Dual RNAscope ISH-IHC
USD :
399 USD
alt names :
API4, apoptosis inhibitor 4, Apoptosis inhibitor survivin, baculoviral IAP repeat-containing 5, Baculoviral IAP Repeat-Containing Protein 5, BIRC5, EPR-1, IAP4, survivin variant 3 alpha
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.