product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
POT1 Antibody
catalog :
NB500-176
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SV5-Pk1
reactivity :
human
application :
western blot
more info or order :
Novus Biologicals product webpage
citations: 24
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 2
Swanson M, Baribault M, Israel J, Bae N. Telomere protein RAP1 levels are affected by cellular aging and oxidative stress. Biomed Rep. 2016;5:181-187 pubmed
Zeng J, Hills S, Ozono E, Diffley J. Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication. Cell. 2023;186:528-542.e14 pubmed publisher
Chen L, Zhang C, Ma W, Huang J, Zhao Y, Liu H. METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability. Nucleic Acids Res. 2022;50:11619-11634 pubmed publisher
Li X, Li X, Xie C, Cai S, Li M, Jin H, et al. cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence. Protein Cell. 2022;13:47-64 pubmed publisher
Yu E, Zahid S, Aloe S, Falck Pedersen E, Zhou X, Cheung N, et al. Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology. Commun Biol. 2021;4:1315 pubmed publisher
Li T, Luo Z, Lin S, Li C, Dai S, Wang H, et al. MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. Aging (Albany NY). 2020;12:14791-14807 pubmed publisher
Wu S, Ge Y, Li X, Yang Y, Zhou H, Lin K, et al. BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1. PLoS Genet. 2020;16:e1008799 pubmed publisher
Yang C, Danielson E, Qiao T, Metterville J, Brown R, Landers J, et al. Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity. Proc Natl Acad Sci U S A. 2016;113:E6209-E6218 pubmed
Walter D, Hoffmann S, Komseli E, Rappsilber J, Gorgoulis V, Sørensen C. SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication. Nat Commun. 2016;7:10530 pubmed publisher
Sishc B, Nelson C, McKenna M, Battaglia C, Herndon A, Idate R, et al. Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis. Front Oncol. 2015;5:257 pubmed publisher
Ci X, Li B, Ma X, Kong F, Zheng C, Björkholm M, et al. Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells. Oncotarget. 2015;6:38079-92 pubmed publisher
Luo Z, Feng X, Wang H, Xu W, Zhao Y, Ma W, et al. Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression. Aging Cell. 2015;14:391-9 pubmed publisher
Ghosh S, Wu M, Shaftel S, Kyrkanides S, LaFerla F, Olschowka J, et al. Sustained interleukin-1? overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. J Neurosci. 2013;33:5053-64 pubmed publisher
Gatherer D, Seirafian S, Cunningham C, Holton M, Dargan D, Baluchova K, et al. High-resolution human cytomegalovirus transcriptome. Proc Natl Acad Sci U S A. 2011;108:19755-60 pubmed publisher
Patino G, Brackenbury W, Bao Y, Lopez Santiago L, O Malley H, Chen C, et al. Voltage-gated Na+ channel ?1B: a secreted cell adhesion molecule involved in human epilepsy. J Neurosci. 2011;31:14577-91 pubmed publisher
Liebau M, Höpker K, Müller R, Schmedding I, Zank S, Schairer B, et al. Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia. J Biol Chem. 2011;286:14237-45 pubmed publisher
Gallazzini M, Heussler G, Kunin M, Izumi Y, Burg M, Ferraris J. High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization. Mol Biol Cell. 2011;22:703-14 pubmed publisher
Herskowitz J, Seyfried N, Gearing M, Kahn R, Peng J, Levey A, et al. Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. J Biol Chem. 2011;286:6117-27 pubmed publisher
Zhao A, Nunez Cruz S, Li C, Coukos G, Siegel D, Scholler N. Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/TEM1, using a paired yeast-display/secretory scFv library platform. J Immunol Methods. 2011;363:221-32 pubmed publisher
Björk J, Sandqvist A, Elsing A, Kotaja N, Sistonen L. miR-18, a member of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis. Development. 2010;137:3177-84 pubmed publisher
Hadler K, Huber T, Cassady A, Weber J, Robinson J, Burrows A, et al. Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases?. BMC Res Notes. 2008;1:78 pubmed publisher
Boggio R, Passafaro A, Chiocca S. Targeting SUMO E1 to ubiquitin ligases: a viral strategy to counteract sumoylation. J Biol Chem. 2007;282:15376-82 pubmed
Sanchez Garcia J, Ciufo L, Yang X, Kearsey S, MacNeill S. The C-terminal zinc finger of the catalytic subunit of DNA polymerase delta is responsible for direct interaction with the B-subunit. Nucleic Acids Res. 2004;32:3005-16 pubmed
Young D, Chatziandreou N, He B, Goodbourn S, Lamb R, Randall R. Single amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cells. J Virol. 2001;75:3363-70 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB500-176
SKU :
NB500-176
product name :
POT1 Antibody
Description :
The POT1 Antibody from Novus is a rabbit polyclonal antibody to POT1. This antibody reacts with human. The POT1 Antibody has been validated for the following applications: Western Blot.
target :
POT1
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human POT1 protein sequence (between residues 200-300). [UniProt# Q9NUX5]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human
theoretical molecular weight :
71.4 kDa
gene symbol :
POT1
accessionNumbers :
Q9NUX5
applications :
Western Blot
USD :
399 USD
alt names :
DKFZp586D211, hPot1, POT1 protection of telomeres 1 homolog, POT1-like telomere end-binding protein, protection of telomeres 1 homolog (S. pombe), protection of telomeres protein 1
storage :
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.