product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Histone H3 Antibody - BSA Free
catalog :
NB500-171
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 52
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 7c
Dhawan U, Bhattacharya P, Narayanan S, Manickam V, Aggarwal A, Subramanian M. Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression. Arterioscler Thromb Vasc Biol. 2021;41:2598-2615 pubmed publisher
Malnar x10c rnigoj M, x10c er x10d ek U, Yin X, Ho M, Repič Lampret B, Neumann M, et al. Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA. Nat Commun. 2023;14:5764 pubmed publisher
Fan M, Yang K, Wang X, Chen L, Gill P, Ha T, et al. Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction. Sci Adv. 2023;9:eadc9465 pubmed publisher
Yang Y, Chen C, Zuo Q, Lu H, Salman S, Lyu Y, et al. NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification. Sci Adv. 2022;8:eabo5000 pubmed publisher
Decker C, Burke J, Mulvaney P, Parker R. RNA is required for the integrity of multiple nuclear and cytoplasmic membrane-less RNP granules. EMBO J. 2022;41:e110137 pubmed publisher
Palombo R, Paronetto M. pncCCND1_B Engages an Inhibitory Protein Network to Downregulate CCND1 Expression upon DNA Damage. Cancers (Basel). 2022;14: pubmed publisher
Rivera C, Lee H, Lappala A, Wang D, Noches V, Olivares Costa M, et al. Unveiling RCOR1 as a rheostat at transcriptionally permissive chromatin. Nat Commun. 2022;13:1550 pubmed publisher
Feng S, Ma S, Li K, Gao S, Ning S, Shang J, et al. RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity. Nat Commun. 2022;13:957 pubmed publisher
Ali F, Mohammed H, Elroby Ali D. Protective effect of hydrogen sulfide against stress-induced lung injury: involvement of Nrf2, NFκB/iNOS, and HIF-1α signaling pathways. Cell Stress Chaperones. 2022;27:55-70 pubmed publisher
Wang J, Liu R, Wang Y, Mo H, Niu Y, Xu Q, et al. Repression of the miR-627-5p by histone deacetylase 3 contributes to hypoxia-induced hepatocellular carcinoma progression. J Cancer. 2021;12:5320-5330 pubmed publisher
Wibisono P, Liu Y, Sun J. A novel in vitro Caenorhabditis elegans transcription system. BMC Mol Cell Biol. 2020;21:87 pubmed publisher
Fan M, Yang K, Wang X, Wang Y, Tu F, Ha T, et al. Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction. JCI Insight. 2020;5: pubmed publisher
Auzmendi Iriarte J, Sáenz Antoñanzas A, Mikelez Alonso I, Carrasco Garcia E, Tellaetxe Abete M, Lawrie C, et al. Characterization of a new small-molecule inhibitor of HDAC6 in glioblastoma. Cell Death Dis. 2020;11:417 pubmed publisher
Tummers B, Mari L, Guy C, Heckmann B, Rodriguez D, Rühl S, et al. Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis. Immunity. 2020;52:994-1006.e8 pubmed publisher
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan N, et al. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness. J Clin Invest. 2020;: pubmed publisher
Lowe D, Herzog M, Mosler T, Cohen H, Felton S, Beli P, et al. Chronic irradiation of human cells reduces histone levels and deregulates gene expression. Sci Rep. 2020;10:2200 pubmed publisher
Ando Y, Ohuchida K, Otsubo Y, Kibe S, Takesue S, Abe T, et al. Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5. PLoS ONE. 2020;15:e0228015 pubmed publisher
Riegger J, Huber Lang M, Brenner R. Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. Osteoarthritis Cartilage. 2020;28:685-697 pubmed publisher
Popper B, Rammer M, Gasparitsch M, Singer T, Keller U, Döring Y, et al. Neonatal obstructive nephropathy induces necroptosis and necroinflammation. Sci Rep. 2019;9:18600 pubmed publisher
Sinha S, Renganathan A, Nagendra P, Bhat V, Mathew B, Rao M. AEBP1 down regulation induced cell death pathway depends on PTEN status of glioma cells. Sci Rep. 2019;9:14577 pubmed publisher
Riegger J, Brenner R. Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis. Cell Death Dis. 2019;10:683 pubmed publisher
Guclu O, Doganlar O, Yuksel V, Doganlar Z. FOLFIRI-Mediated Toxicity in Human Aortic Smooth Muscle Cells and Possible Amelioration with Curcumin and Quercetin. Cardiovasc Toxicol. 2019;: pubmed publisher
Chen S, Yang C, Sun C, Sun Y, Yang Z, Cheng S, et al. miR-21-5p Suppressed the Sensitivity of Hepatocellular Carcinoma Cells to Cisplatin by Targeting FASLG. DNA Cell Biol. 2019;38:865-873 pubmed publisher
Xu S, Luo W, Xu X, Qian Y, Xu Z, Yu W, et al. MD2 blockade prevents oxLDL-induced renal epithelial cell injury and protects against high-fat-diet-induced kidney dysfunction. J Nutr Biochem. 2019;70:47-55 pubmed publisher
Doganlar Z, Guclu H, Öztopuz Ö, Turkon H, Doğan A, Uzun M, et al. The Role of Melatonin in Oxidative Stress, DNA Damage, Apoptosis and Angiogenesis in Fetal Eye under Preeclampsia and Melatonin Deficiency Stress. Curr Eye Res. 2019;44:1157-1169 pubmed publisher
Messenger Z, Hall J, Jima D, House J, Tam H, Tokarz D, et al. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis. 2018;9:1054 pubmed publisher
Zhang Y, Akumuo R, Espana R, Yan C, Gao W, Li Y. The histone demethylase KDM6B in the medial prefrontal cortex epigenetically regulates cocaine reward memory. Neuropharmacology. 2018;141:113-125 pubmed publisher
Turtle J, Strain M, Reynolds J, Huang Y, Lee K, Henwood M, et al. Pain Input After Spinal Cord Injury (SCI) Undermines Long-Term Recovery and Engages Signal Pathways That Promote Cell Death. Front Syst Neurosci. 2018;12:27 pubmed publisher
Lu H, Tran L, Park Y, Chen I, Lan J, Xie Y, et al. Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment. Cancer Res. 2018;78:4191-4202 pubmed publisher
Wiberg R, Novikova L, Kingham P. Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. Neuroreport. 2018;29:779-785 pubmed publisher
Guclu H, Doganlar Z, Gürlü V, Özal A, Doğan A, Turhan M, et al. Effects of cisplatin-5-fluorouracil combination therapy on oxidative stress, DNA damage, mitochondrial apoptosis, and death receptor signalling in retinal pigment epithelium cells. Cutan Ocul Toxicol. 2018;37:291-304 pubmed publisher
Lotti R, Shu E, Petrachi T, Marconi A, Palazzo E, Quadri M, et al. Soluble Fas Ligand Is Essential for Blister Formation in Pemphigus. Front Immunol. 2018;9:370 pubmed publisher
Philion C, Ma D, Ruvinov I, Mansour F, Pignanelli C, Noel M, et al. Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo. Oncotarget. 2017;8:110756-110773 pubmed publisher
Xu Y, Ning S, Wei Z, Xu R, Xu X, Xing M, et al. 53BP1 and BRCA1 control pathway choice for stalled replication restart. elife. 2017;6: pubmed publisher
Tian J, Guo S, Chen H, Peng J, Jia M, Li N, et al. Combination of Emricasan with Ponatinib Synergistically Reduces Ischemia/Reperfusion Injury in Rat Brain Through Simultaneous Prevention of Apoptosis and Necroptosis. Transl Stroke Res. 2018;9:382-392 pubmed publisher
Li F, Wang T, Wang Z, Chen X, Liu R. Histone deacetylase inhibitor quisinostat activates caspase signaling and upregulates p53 acetylation to inhibit the proliferation of HepG2 cells. Mol Med Rep. 2017;16:6094-6101 pubmed publisher
Zhou X, Xie L, Xia L, Bergmann F, Buchler M, Kroemer G, et al. RIP3 attenuates the pancreatic damage induced by deletion of ATG7. Cell Death Dis. 2017;8:e2918 pubmed publisher
Liu P, Hu Y, Kang B, Tseng Y, Wu P, Liang C, et al. Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma. PLoS ONE. 2017;12:e0180620 pubmed publisher
Gulchina Y, Xu S, Snyder M, Elefant F, Gao W. Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia. J Neurochem. 2017;143:320-333 pubmed publisher
Xiao J, Yao J, Jia L, Lin C, Zacks D. Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate Injury. Invest Ophthalmol Vis Sci. 2017;58:1801-1810 pubmed publisher
Chi W, Hua X, Chen X, Bian F, Yuan X, Zhang L, et al. Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. J Autoimmun. 2017;80:65-76 pubmed publisher
Gao Y, Yang H, Fan Y, Li L, Fang J, Yang W. Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis. Mediators Inflamm. 2016;2016:1320365 pubmed publisher
Wu C, Cheng C, Lee Y, Chang I, Chen H, Hsieh C, et al. Ursolic Acid Triggers Apoptosis in Human Osteosarcoma Cells via Caspase Activation and the ERK1/2 MAPK Pathway. J Agric Food Chem. 2016;64:4220-6 pubmed publisher
Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, et al. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016;97:1-14 pubmed publisher
Fan W, Li X, Yao H, Deng J, Liu H, Cui Z, et al. Neural differentiation and synaptogenesis in retinal development. Neural Regen Res. 2016;11:312-8 pubmed publisher
Baquedano E, Burgos Ramos E, Canelles S, González Rodríguez A, Chowen J, Argente J, et al. Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model. Dis Model Mech. 2016;9:573-83 pubmed publisher
Cheng C, Cheng Y, Chang I, Chen H, Wu C, Hsieh C. Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells. Mol Med Rep. 2016;13:1495-500 pubmed publisher
Matzke Ogi A, Jannasch K, Shatirishvili M, Fuchs B, Chiblak S, Morton J, et al. Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling. Gastroenterology. 2016;150:513-25.e10 pubmed publisher
Thamizhiniyan V, Young Woong C, Young Kyoon K. The cytotoxic nature of Acanthopanax sessiliflorus stem bark extracts in human breast cancer cells. Saudi J Biol Sci. 2015;22:752-9 pubmed publisher
Wang L, Wu L, Wang X, Deng J, Ma Z, Fan W, et al. Prenatal alcohol exposure inducing the apoptosis of mossy cells in hippocampus of SMS2-/- mice. Environ Toxicol Pharmacol. 2015;40:975-82 pubmed publisher
Seko Y, Fujimura T, Yao T, Taka H, Mineki R, Okumura K, et al. Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis. Sci Rep. 2015;5:13737 pubmed publisher
El Hawary M, Abdel Halim M, Sayed S, Abdelkader H. Apocytolysis, a proposed mechanism of blister formation in epidermolysis bullosa simplex. Arch Dermatol Res. 2015;307:371-7 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB500-171
SKU :
NB500-171
product name :
Histone H3 Antibody - BSA Free
Description :
The Histone H3 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Histone H3. This antibody reacts with human, mouse, rat, insect, xenopus, yeast. The Histone H3 Antibody - BSA Free has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunoblotting, Chromatin Immunoprecipitation (ChIP), Single Cell Western.
target :
Histone H3
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS (pH 7.4)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This Histone H3 antibody was raised against a synthetic peptide made to an C-terminal portion of the human Histone H3 protein (between residues 100-136) [UniProt P68431]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat, Insect, Xenopus, Yeast
theoretical molecular weight :
15 kDa
gene symbol :
H3C14
accessionNumbers :
P68431
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunoblotting, Chromatin Immunoprecipitation (ChIP), Single Cell Western
USD :
399 USD
alt names :
H3, H3 histone, family 3A, H3.3A, H3.3B, H3F2, H3F3, H3F3B, H3FM, HIST2H3C, histone H3.3, MGC87782, MGC87783
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.