product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
KAP1 Antibody
catalog :
NB500-158
quantity :
100 ul
price :
449 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
2D8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 17
Reference
Yang Y, Lu H, Chen C, Lyu Y, Cole R, Semenza G. HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia. Nat Commun. 2022;13:316 pubmed publisher
Chang J, Hwang H, Kim B, Choi Y, Park J, Park Y, et al. TRIM28 functions as a negative regulator of aggresome formation. Autophagy. 2021;:1-17 pubmed publisher
Sorrentino G, Rezakhani S, Yıldız E, Nuciforo S, Heim M, Lutolf M, et al. Mechano-modulatory synthetic niches for liver organoid derivation. Nat Commun. 2020;11:3416 pubmed publisher
Upmanyu N, Bulldan A, Failing K, Scheiner Bobis G. DHEAS prevents pro-metastatic and proliferative effects of 17ß-estradiol on MCF-7 breast cancer cells. Biochim Biophys Acta Mol Cell Res. 2020;1867:118600 pubmed publisher
Wenstedt E, Verberk S, Kroon J, Neele A, Baardman J, Claessen N, et al. Salt increases monocyte CCR2 expression and inflammatory responses in humans. JCI Insight. 2019;4: pubmed publisher
Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher
Do C, Drel V, Tan C, Lee D, Wagner B. 'Nephrogenic' systemic fibrosis is mediated by myeloid C-C chemokine receptor 2. J Invest Dermatol. 2019;: pubmed publisher
Rojo J, Jaworski J, PELUFFO M. Direct role of the C-C motif chemokine receptor 2/monocyte chemoattractant protein 1 system in the feline cumulus oocyte complex†. Biol Reprod. 2019;100:1046-1056 pubmed publisher
Béke G, Dajnoki Z, Kapitany A, Gáspár K, Medgyesi B, Poliska S, et al. Immunotopographical Differences of Human Skin. Front Immunol. 2018;9:424 pubmed publisher
Garzia L, Kijima N, Morrissy A, De Antonellis P, Guerreiro Stucklin A, Holgado B, et al. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 2018;172:1050-1062.e14 pubmed publisher
Linde N, Casanova Acebes M, Sosa M, Mortha A, Rahman A, Farias E, et al. Macrophages orchestrate breast cancer early dissemination and metastasis. Nat Commun. 2018;9:21 pubmed publisher
Zhi L, Yao S, Liu H, Li M, Duan N, Ma J. Hydroxytyrosol inhibits the inflammatory response of osteoarthritis chondrocytes via SIRT6-mediated autophagy. Mol Med Rep. 2018;17:4035-4042 pubmed publisher
Kuwahara G, Hashimoto T, Tsuneki M, Yamamoto K, Assi R, Foster T, et al. CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation. Arterioscler Thromb Vasc Biol. 2017;37:1147-1156 pubmed publisher
Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed publisher
Yamamoto S, Zhong J, Yancey P, Zuo Y, Linton M, Fazio S, et al. Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype. Atherosclerosis. 2015;242:56-64 pubmed publisher
Batenburg N, Thompson E, Hendrickson E, Zhu X. Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO J. 2015;34:1399-416 pubmed publisher
Chen S, Jiao J, Jiang D, Wan Z, Li L, Li K, et al. T-box transcription factor Brachyury in lung cancer cells inhibits macrophage infiltration by suppressing CCL2 and CCL4 chemokines. Tumour Biol. 2015;36:5881-90 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB500-158
SKU :
NB500-158
product name :
KAP1 Antibody
Description :
The KAP1 Antibody from Novus is a rabbit polyclonal antibody to KAP1. This antibody reacts with human, mouse. The KAP1 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Chromatin Immunoprecipitation (ChIP).
target :
KAP1
category :
Primary Antibodies
unit size :
100 ul
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human Tripartite Motif-Containing 28 using the numbering given in entry NP_005753.1 (GeneID 10155).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse
gene symbol :
TRIM28
accessionNumbers :
Q13263
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Chromatin Immunoprecipitation (ChIP)
USD :
449 USD
alt names :
E3 SUMO-protein ligase TRIM28, EC 6.3.2.-, FLJ29029, KAP-1, KAP1KRAB-associated protein 1, KRIP-1, Nuclear corepressor KAP-1, RNF96KRAB-interacting protein 1, TF1B, TIF1-beta, TIF1BRING finger protein 96, transcription intermediary factor 1-beta, transcriptional intermediary factor 1-beta, tripartite motif containing 28, tripartite motif-containing 28, Tripartite motif-containing protein 28
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.