This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MRP1 Antibody (IU2H10)
catalog :
NB400-156
quantity :
0.1 ml (also 0.025 ml)
price :
329 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IU2H10
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 19
Reference
Huang R, Zhu L, Zhang Y. XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way. Cancer Cell Int. 2020;20:436 pubmed publisher
Jing Y, Dai X, Yang L, Kang D, Jiang P, Li N, et al. STING couples with PI3K to regulate actin reorganization during BCR activation. Sci Adv. 2020;6:eaax9455 pubmed publisher
Sridharan S, Robeson M, Bastihalli Tukaramrao D, Howard C, Subramaniyan B, Tilley A, et al. Targeting of the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front Oncol. 2019;9:1311 pubmed publisher
Zhang S, Chatterjee T, Godoy C, Wu L, Liu Q, Carmon K. GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism. Mol Cancer Res. 2019;17:2196-2207 pubmed publisher
Yang H, Lee W, Kong S, Kim C, Kim J, Chang S, et al. STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade. J Clin Invest. 2019;129:4350-4364 pubmed publisher
Li K, Ouyang L, He M, Luo M, Cai W, Tu Y, et al. IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway. Oncotarget. 2017;8:28865-28879 pubmed publisher
Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, et al. RAD51 interconnects between DNA replication, DNA repair and immunity. Nucleic Acids Res. 2017;45:4590-4605 pubmed publisher
Reinert L, Lopušná K, Winther H, Sun C, Thomsen M, Nandakumar R, et al. Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. Nat Commun. 2016;7:13348 pubmed publisher
Li T, Cheng H, Yuan H, Xu Q, Shu C, Zhang Y, et al. Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response. Sci Rep. 2016;6:19049 pubmed publisher
Koshkin V, Ailles L, Liu G, Krylov S. Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells. J Cell Biochem. 2016;117:59-65 pubmed publisher
Grybauskas A, Koga T, Kuprys P, Nolan M, McCarty R, Walker L, et al. ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. Mol Vis. 2015;21:201-12 pubmed
Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher
Kurihara Y, Sawazumi T, Takeuchi T. Exploration of interactions between membrane proteins embedded in supported lipid bilayers and their antibodies by reflectometric interference spectroscopy-based sensing. Analyst. 2014;139:6016-21 pubmed publisher
Chen Y, Lukka P, Joseph W, Finlay G, Paxton J, McKeage M, et al. Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent. Cancer Chemother Pharmacol. 2014;74:25-35 pubmed publisher
Tiwari A, Zhang R, Gallo J. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models. Mol Cancer Ther. 2013;12:1343-55 pubmed publisher
Chen Q, Yang Y, Li L, Zhang J. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. J Biol Chem. 2006;281:31152-63 pubmed
Binyamin L, Assaraf Y, Reiter Y. Probing ATP-dependent conformational changes in the multidrug resistance protein 1 (MRP1/ABCC1) in live tumor cells with a novel recombinant single-chain Fv antibody targeted to the extracellular N-terminus. Int J Cancer. 2005;116:703-9 pubmed
Yang Y, Chen Q, Zhang J. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. J Biol Chem. 2002;277:44268-77 pubmed
Chen Q, Yang Y, Liu Y, Han B, Zhang J. Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1. Biochemistry. 2002;41:9052-62 pubmed
product information
brand :
Novus
master code :
NB400-156
SKU :
NB400-156-0.1ml
product name :
MRP1 Antibody (IU2H10)
description :
The MRP1 Antibody (IU2H10) from Novus Biologicals is a mouse monoclonal antibody to MRP1. This antibody reacts with human, mouse, rat. The MRP1 Antibody (IU2H10) has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, CyTOF-ready, Dual RNAscope ISH-IHC.
target :
MRP1
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Monoclonal
clone :
IU2H10
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant peptide (a.a. 1-33) of human MRP1. [UniProt# P33527].
isotype :
IgG1
purity :
Protein G purified
species :
Human, Mouse, Rat
gene symbol :
ABCC1
catalog number base :
NB400-156
applications :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, CyTOF-ready, Dual RNAscope ISH-IHC
2020 USD :
329
2021 USD :
329 USD
alt names :
ABC29, ABCC, ATP-binding cassette sub-family C member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, EC 3.6.3, EC 3.6.3.44, GS-X, Leukotriene C(4) transporter, LTC4 transporter, MRP1DKFZp781G125, MRPDKFZp686N04233, multidrug resistance associated protein 1, multidrug resistance protein, multidrug resistance-associated protein 1, multiple drug resistance protein 1, multiple drug resistance-associated protein
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.