MRP1 Antibody (IU2H10) - BSA Free | Novus Biologicals NB400-156-0.1ml product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MRP1 Antibody (IU2H10) - BSA Free

catalog :

NB400-156-0.1ml

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

IU2H10

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Novus Biologicals product webpage

citations: 16

Reference
Zhang W, Liu Q, Haqqani A, Liu Z, Sodja C, Leclerc S, et al. Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat. Pharmaceutics. 2023;15: pubmed publisher
Doganlar O, Doganlar Z, Erdogan S, Delen E. Antineoplastic multi-drug chemotherapy to sensitize tumors triggers multi-drug resistance and inhibits efficiency of maintenance treatment inglioblastoma cells. EXCLI J. 2023;22:35-52 pubmed publisher
Bhadwal P, Randhawa V, Vaiphei K, Dahiya D, Agnihotri N. Clinical relevance of CERK and SPHK1 in breast cancer and their association with metastasis and drug resistance. Sci Rep. 2022;12:18239 pubmed publisher
Huang R, Zhu L, Zhang Y. XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way. Cancer Cell Int. 2020;20:436 pubmed publisher
Sridharan S, Robeson M, Bastihalli Tukaramrao D, Howard C, Subramaniyan B, Tilley A, et al. Targeting of the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front Oncol. 2019;9:1311 pubmed publisher
Zhang S, Chatterjee T, Godoy C, Wu L, Liu Q, Carmon K. GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism. Mol Cancer Res. 2019;17:2196-2207 pubmed publisher
Li K, Ouyang L, He M, Luo M, Cai W, Tu Y, et al. IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway. Oncotarget. 2017;8:28865-28879 pubmed publisher
Koshkin V, Ailles L, Liu G, Krylov S. Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells. J Cell Biochem. 2016;117:59-65 pubmed publisher
Grybauskas A, Koga T, Kuprys P, Nolan M, McCarty R, Walker L, et al. ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. Mol Vis. 2015;21:201-12 pubmed
Kurihara Y, Sawazumi T, Takeuchi T. Exploration of interactions between membrane proteins embedded in supported lipid bilayers and their antibodies by reflectometric interference spectroscopy-based sensing. Analyst. 2014;139:6016-21 pubmed publisher
Chen Y, Lukka P, Joseph W, Finlay G, Paxton J, McKeage M, et al. Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent. Cancer Chemother Pharmacol. 2014;74:25-35 pubmed publisher
Tiwari A, Zhang R, Gallo J. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models. Mol Cancer Ther. 2013;12:1343-55 pubmed publisher
Chen Q, Yang Y, Li L, Zhang J. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. J Biol Chem. 2006;281:31152-63 pubmed
Binyamin L, Assaraf Y, Reiter Y. Probing ATP-dependent conformational changes in the multidrug resistance protein 1 (MRP1/ABCC1) in live tumor cells with a novel recombinant single-chain Fv antibody targeted to the extracellular N-terminus. Int J Cancer. 2005;116:703-9 pubmed
Yang Y, Chen Q, Zhang J. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. J Biol Chem. 2002;277:44268-77 pubmed
Chen Q, Yang Y, Liu Y, Han B, Zhang J. Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1. Biochemistry. 2002;41:9052-62 pubmed

product information

master code :

NB400-156

SKU :

NB400-156-0.1ml

product name :

MRP1 Antibody (IU2H10) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The MRP1 Antibody (IU2H10) - BSA Free from Novus is a mouse monoclonal antibody to MRP1. This antibody reacts with human,mouse,rat. The MRP1 Antibody (IU2H10) - BSA Free has been validated for the following applications: ELISA,Flow Cytometry,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,Immunohistochemistry,CyTOF-ready,Dual RNAscope ISH-IHC.

target :

MRP1

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

IU2H10

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant peptide (a.a. 1-33) of human MRP1. [UniProt# P33527].

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse,Rat

gene symbol :

ABCC1

Antibody validation :

Orthogonal Validation

applications :

ELISA,Flow Cytometry,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,Immunohistochemistry,CyTOF-ready,Dual RNAscope ISH-IHC

USD :

409 USD

alt names :

ABC29, ABCC, ATP-binding cassette sub-family C member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, EC 3.6.3, EC 3.6.3.44, GS-X, Leukotriene C(4) transporter, LTC4 transporter, MRP1DKFZp781G125, MRPDKFZp686N04233, multidrug resistance associated protein 1, multidrug resistance protein, multidrug resistance-associated protein 1, multiple drug resistance protein 1, multiple drug resistance-associated protein

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage