product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MafA Antibody - BSA Free
catalog :
NB400-137
quantity :
100 ul
price :
499 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
DyLight 650
clone name :
H3
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Reference
Lin H, Yu I, Cheng M, Chang T, Lin H, Chang Y, et al. Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA. Nat Commun. 2024;15:10537 pubmed publisher
Worthy A, Anderson J, Lane A, Gomez Perez L, Wang A, Griffith R, et al. Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity. elife. 2024;13: pubmed publisher
Becker A, Wardas B, Salah H, Amini M, Fecher Trost C, Sen Q, et al. Cavβ3 Regulates Ca2+ Signaling and Insulin Expression in Pancreatic β-Cells in a Cell-Autonomous Manner. Diabetes. 2021;70:2532-2544 pubmed publisher
Yoshihara E, O Connor C, Gasser E, Wei Z, Oh T, Tseng T, et al. Immune-evasive human islet-like organoids ameliorate diabetes. Nature. 2020;586:606-611 pubmed publisher
Mahaddalkar P, Scheibner K, Pfluger S, Ansarullah -, Sterr M, Beckenbauer J, et al. Generation of pancreatic β cells from CD177+ anterior definitive endoderm. Nat Biotechnol. 2020;38:1061-1072 pubmed publisher
Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto A, et al. Vitamin D Switches BAF Complexes to Protect β Cells. Cell. 2018;173:1135-1149.e15 pubmed publisher
Sweeney L, Bikoff J, Gabitto M, Brenner Morton S, Baek M, Yang J, et al. Origin and Segmental Diversity of Spinal Inhibitory Interneurons. Neuron. 2018;97:341-355.e3 pubmed publisher
Akai R, Hosoda A, Yoshino M, Iwawaki T. Constitutive role of GADD34 and CReP in cancellation of phospho-eIF2α-dependent translational attenuation and insulin biosynthesis in pancreatic β cells. Genes Cells. 2015;20:871-86 pubmed publisher
Blanchet E, Van de Velde S, Matsumura S, Hao E, LeLay J, KAESTNER K, et al. Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance. Cell Rep. 2015;10:1149-57 pubmed publisher
product information
brand :
Novus
catalog number base :
NB400-137
SKU :
NB400-137
product name :
MafA Antibody - BSA Free
units size :
100 ul
description :
The MafA Antibody - BSA Free from Novus is a rabbit polyclonal antibody to MafA. This antibody reacts with human,mouse. The MafA Antibody - BSA Free has been validated for the following applications: Chemotaxis,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Gel Super Shift Assays,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence.
target :
MafA
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 300 and the C-terminus (residue 359) of mouse v-maf musculoaponeurotic fibrosarcoma oncogene homolog A using the numbering given in entry NP_919331.1 (GeneID 378435).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
MAFA
review stars :
5
top caption :
Western Blot: MafA Antibody [NB400-137]
accessionNumbers :
Q8CF90
applications :
Chemotaxis,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Gel Super Shift Assays,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence
USD :
499 USD
alt names :
hMafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3B1, transcription factor MafA, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.