| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig s4d
| Schlein C, Fischer A, Sass F, Worthmann A, Tödter K, Jaeckstein M, et al. Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Rep. 2021;34:108624 pubmed publisher |
- western blot; mouse; fig 6a
| Carroll P, Freie B, Cheng P, Kasinathan S, Gu H, Hedrich T, et al. The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis. PLoS Biol. 2021;19:e3001085 pubmed publisher |
- western blot; human; loading ...; fig 2b
- immunohistochemistry - paraffin section; mouse; loading ...; fig 6b
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| Hsiao W, Jung S, Tang Y, Haley J, Li R, Li H, et al. The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development. Cell Rep. 2020;33:108223 pubmed publisher |
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| Morigny P, Houssier M, Mairal A, Ghilain C, Mouisel E, Benhamed F, et al. Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity. Nat Metab. 2019;1:133-146 pubmed publisher |
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| Fan Q, Nørgaard R, Grytten I, Ness C, Lucas C, Vekterud K, et al. LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction. Cells. 2020;9: pubmed publisher |
| Milutinović D, Brkljacic J, Teofilović A, Bursać B, Nikolic M, Gligorovska L, et al. Chronic Stress Potentiates High Fructose-Induced Lipogenesis in Rat Liver and Kidney. Mol Nutr Food Res. 2020;64:e1901141 pubmed publisher |
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| Tong X, Zhang D, Shabandri O, Oh J, Jin E, Stamper K, et al. DDB1 E3 ligase controls dietary fructose-induced ChREBPα stabilization and liver steatosis via CRY1. Metabolism. 2020;107:154222 pubmed publisher |
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| Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, et al. ChREBP-β regulates thermogenesis in brown adipose tissue. J Endocrinol. 2020;245:343-356 pubmed publisher |
| Lei Y, Zhou S, Hu Q, Chen X, Gu J. Carbohydrate response element binding protein (ChREBP) correlates with colon cancer progression and contributes to cell proliferation. Sci Rep. 2020;10:4233 pubmed publisher |
| Zhao C, Liu L, Liu Q, Li F, Zhang L, Zhu F, et al. Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice. Mol Metab. 2019;29:145-157 pubmed publisher |
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| Kumar A, Katz L, Schulz A, Kim M, Honig L, Li L, et al. Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation. Diabetes. 2018;67:1561-1575 pubmed publisher |
| Singh K, Kim S, Hahm E, Pore S, Jacobs B, Singh S. Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism. Carcinogenesis. 2018;39:826-837 pubmed publisher |
| Linden A, Li S, Choi H, Fang F, Fukasawa M, Uyeda K, et al. Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice. J Lipid Res. 2018;59:475-487 pubmed publisher |
| Kim M, Astapova I, Flier S, Hannou S, Doridot L, Sargsyan A, et al. Intestinal, but not hepatic, ChREBP is required for fructose tolerance. JCI Insight. 2017;2: pubmed publisher |
| Sanchez Gurmaches J, Tang Y, Jespersen N, Wallace M, Martinez Calejman C, Gujja S, et al. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metab. 2018;27:195-209.e6 pubmed publisher |
| Katz L, Xu S, Ge K, Scott D, Gershengorn M. T3 and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice. Endocrinology. 2018;159:557-569 pubmed publisher |
| Kim Y, Kim M, Choi M, Lee D, Roh G, Kim H, et al. Aralia elata (Miq) Seem Extract Decreases O-GlcNAc Transferase Expression and Retinal Cell Death in Diabetic Mice. J Med Food. 2017;20:989-1001 pubmed publisher |
| Iroz A, Montagner A, Benhamed F, Levavasseur F, Polizzi A, Anthony E, et al. A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response. Cell Rep. 2017;21:403-416 pubmed publisher |
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| Heidenreich S, Witte N, WEBER P, Goehring I, Tolkachov A, von Loeffelholz C, et al. Retinol saturase coordinates liver metabolism by regulating ChREBP activity. Nat Commun. 2017;8:384 pubmed publisher |
| Kim Y, Kim M, Choi M, Lee D, Roh G, Kim H, et al. Metformin protects against retinal cell death in diabetic mice. Biochem Biophys Res Commun. 2017;492:397-403 pubmed publisher |
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| Fan Q, Nørgaard R, Bindesbøll C, Lucas C, Dalen K, Babaie E, et al. LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice. Nutrients. 2017;9: pubmed publisher |
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| Cao W, Chang T, Li X, Wang R, Wu L. Dual effects of fructose on ChREBP and FoxO1/3α are responsible for AldoB up-regulation and vascular remodelling. Clin Sci (Lond). 2017;131:309-325 pubmed publisher |
| McMurphy T, Huang W, Xiao R, Liu X, Dhurandhar N, Cao L. Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation. Diabetes. 2017;66:358-371 pubmed publisher |
| Kim M, Krawczyk S, Doridot L, Fowler A, Wang J, Trauger S, et al. ChREBP regulates fructose-induced glucose production independently of insulin signaling. J Clin Invest. 2016;126:4372-4386 pubmed publisher |
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| Schmidt S, Madsen J, Frafjord K, Poulsen L, Salö S, Boergesen M, et al. Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-ROR? Axis Regulating Proliferation in ? Cells. Cell Rep. 2016;16:2359-72 pubmed publisher |
| Marmugi A, Lukowicz C, Lasserre F, Montagner A, Polizzi A, Ducheix S, et al. Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way. Toxicol Appl Pharmacol. 2016;303:90-100 pubmed publisher |
| Tang Y, Wallace M, Sanchez Gurmaches J, Hsiao W, Li H, Lee P, et al. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism. Nat Commun. 2016;7:11365 pubmed publisher |
| Kitsunai H, Makino Y, Sakagami H, Mizumoto K, Yanagimachi T, Atageldiyeva K, et al. High glucose induces platelet-derived growth factor-C via carbohydrate response element-binding protein in glomerular mesangial cells. Physiol Rep. 2016;4: pubmed publisher |
| Zhang Z, Li B, Meng X, Yao S, Jin L, Yang J, et al. Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress. Sci Rep. 2016;6:20848 pubmed publisher |
| Nuotio Antar A, Poungvarin N, Li M, Schupp M, Mohammad M, Gerard S, et al. FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance. Endocrinology. 2015;156:4020-32 pubmed publisher |
| Witte N, Muenzner M, Rietscher J, Knauer M, Heidenreich S, Nuotio Antar A, et al. The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation. Endocrinology. 2015;156:4008-19 pubmed publisher |
| Li X, Kover K, Heruth D, Watkins D, Moore W, Jackson K, et al. New Insight Into Metformin Action: Regulation of ChREBP and FOXO1 Activities in Endothelial Cells. Mol Endocrinol. 2015;29:1184-94 pubmed publisher |
| Trabelsi M, Daoudi M, Prawitt J, Ducastel S, Touche V, Sayin S, et al. Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells. Nat Commun. 2015;6:7629 pubmed publisher |
| Marmier S, Dentin R, Daujat Chavanieu M, Guillou H, Bertrand Michel J, Gerbal Chaloin S, et al. Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking. Hepatology. 2015;62:1086-100 pubmed publisher |
| Poungvarin N, Chang B, Imamura M, Chen J, Moolsuwan K, Sae Lee C, et al. Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin. Endocrinology. 2015;156:1982-94 pubmed publisher |
| Bindesbøll C, Fan Q, Nørgaard R, MacPherson L, Ruan H, Wu J, et al. Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. J Lipid Res. 2015;56:771-85 pubmed publisher |
| Kaadige M, Yang J, Wilde B, Ayer D. MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction. Mol Cell Biol. 2015;35:101-10 pubmed publisher |
