| Reference |
|---|
Zierke L, John D, Gischke M, Tran Q, Sendler M, Weiss F, et al. Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules. Cell Mol Life Sci. 2024;81:207 pubmed publisher |
B xf6 ing C, Di Fabrizio M, Burger D, Bol J, Huisman E, Rozemuller A, et al. Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy. Brain. 2024;147:3727-3741 pubmed publisher |
Su J, Hong Y, Han C, Yu J, Guan X, Zhu Y, et al. Dual action of macrophage miR-204 confines cyclosporine A-induced atherosclerosis. Br J Pharmacol. 2023;: pubmed publisher |
Subkhangulova A, Gonzalez Lozano M, Groffen A, van Weering J, Smit A, Toonen R, et al. Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons. elife. 2023;12: pubmed publisher |
Jorge Oliva M, Smits J, Wiersma V, Hoozemans J, Scheper W. Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology. Alzheimers Res Ther. 2022;14:187 pubmed publisher |
Gletten R, Cantrell L, Bhattacharya S, Schey K. Lens Aquaporin-5 Inserts Into Bovine Fiber Cell Plasma Membranes Via Unconventional Protein Secretion. Invest Ophthalmol Vis Sci. 2022;63:5 pubmed publisher |
Lee J, Yang D, Goulbourne C, Im E, Stavrides P, Pensalfini A, et al. Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques. Nat Neurosci. 2022;: pubmed publisher |
Bertolin J, Sanchez V, Ribera A, Jaén M, Garcia M, Pujol A, et al. Treatment of skeletal and non-skeletal alterations of Mucopolysaccharidosis type IVA by AAV-mediated gene therapy. Nat Commun. 2021;12:5343 pubmed publisher |
van der Lienden M, Aten J, Marques A, Waas I, Larsen P, Claessen N, et al. GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice. Int J Mol Sci. 2021;22: pubmed publisher |
Hozain S, Cottrell J. CDllb+ targeted depletion of macrophages negatively affects bone fracture healing. Bone. 2020;138:115479 pubmed publisher |
Mokshagundam S, Ding T, Rumph J, Dallas M, Stephens V, Osteen K, et al. Developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure of either parent enhances the risk of necrotizing enterocolitis in neonatal mice. Birth Defects Res. 2020;112:1209-1223 pubmed publisher |
Vasiukov G, Novitskaya T, Zijlstra A, Owens P, Ye F, Zhao Z, et al. Myeloid Cell-Derived TGFβ Signaling Regulates ECM Deposition in Mammary Carcinoma via Adenosine-Dependent Mechanisms. Cancer Res. 2020;80:2628-2638 pubmed publisher |
Lee J, Wolfe D, Darji S, McBrayer M, Colacurcio D, Kumar A, et al. β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7. J Mol Biol. 2020;432:2633-2650 pubmed publisher |
Li L, Ni L, Heary R, Elkabes S. Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury. J Neuroinflammation. 2020;17:73 pubmed publisher |
Hasenour C, KENNEDY A, Bednarski T, Trenary I, Eudy B, da Silva R, et al. Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice. J Lipid Res. 2020;61:707-721 pubmed publisher |
Zou D, Pei J, Lan J, Sang H, Chen H, Yuan H, et al. A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption. EBioMedicine. 2020;52:102652 pubmed publisher |
Novitskiy S, Zaynagetdinov R, Vasiukov G, Gutor S, Han W, Serezani A, et al. Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis. Oncotarget. 2019;10:7031-7042 pubmed publisher |
Matoba H, Takamoto M, Fujii C, Kawakubo M, Kasuga E, Matsumura T, et al. Cecal Tumorigenesis in Aryl Hydrocarbon Receptor-Deficient Mice Depends on Cecum-Specific Mitogen-Activated Protein Kinase Pathway Activation and Inflammation. Am J Pathol. 2020;190:453-468 pubmed publisher |
Wiersma V, van Ziel A, Vazquez Sanchez S, Nölle A, Berenjeno Correa E, Bonaterra Pastra A, et al. Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology. Acta Neuropathol. 2019;138:943-970 pubmed publisher |
Terasaki Y, Terasaki M, Kanazawa S, Kokuho N, Urushiyama H, Kajimoto Y, et al. Effect of H2 treatment in a mouse model of rheumatoid arthritis-associated interstitial lung disease. J Cell Mol Med. 2019;23:7043-7053 pubmed publisher |
Malla S, Krueger B, Wartmann T, Sendler M, Mahajan U, Weiss F, et al. Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice. Cell Mol Life Sci. 2019;: pubmed publisher |
Sun L, Tijsma A, Mirabelli C, Baggen J, Wahedi M, Franco D, et al. Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence. Emerg Microbes Infect. 2019;8:1076-1085 pubmed publisher |
Tan W, Tang H, Jiang X, Ye F, Huang L, Shi D, et al. Metformin mediates induction of miR-708 to inhibit self-renewal and chemoresistance of breast cancer stem cells through targeting CD47. J Cell Mol Med. 2019;23:5994-6004 pubmed publisher |
Tawfik A, Knight P, Duckworth C, Pritchard D, Rhodes J, Campbell B. Replication of Crohn's Disease Mucosal E. coli Isolates inside Macrophages Correlates with Resistance to Superoxide and Is Dependent on Macrophage NF-kappa B Activation. Pathogens. 2019;8: pubmed publisher |
Oo Z, Proctor M, Stevenson A, Nazareth D, Fernando M, Daignault S, et al. Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine. Mol Oncol. 2019;13:1503-1518 pubmed publisher |
He Y, Li S, Tang D, Peng Y, Meng J, Peng S, et al. Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation. Free Radic Biol Med. 2019;137:24-36 pubmed publisher |
Lei J, Vermillion M, Jia B, Xie H, Xie L, McLane M, et al. IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection. JCI Insight. 2019;4: pubmed publisher |
Bhatia S, Oweida A, Lennon S, Darragh L, Milner D, Phan A, et al. Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers. Cancer Res. 2019;79:2722-2735 pubmed publisher |
Terasaki Y, Suzuki T, Tonaki K, Terasaki M, Kuwahara N, Ohsiro J, et al. Molecular hydrogen attenuates gefitinib-induced exacerbation of naphthalene-evoked acute lung injury through a reduction in oxidative stress and inflammation. Lab Invest. 2019;99:793-806 pubmed publisher |
May Zhang L, Chen Z, Dosoky N, Yancey P, Boyd K, Hasty A, et al. Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor-/- Mice Improves Indices of Cardiometabolic Disease. Sci Rep. 2019;9:420 pubmed publisher |
Laroumanie F, Korneva A, Bersi M, Alexander M, Xiao L, Zhong X, et al. LNK deficiency promotes acute aortic dissection and rupture. JCI Insight. 2018;3: pubmed publisher |
Zhang Y, Kirane A, Huang H, Sorrelle N, Burrows F, Dellinger M, et al. Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer. Mol Cancer Res. 2019;17:348-355 pubmed publisher |
Kim S, Park J, Kim M, Jang B, Jeon Y, Kim H, et al. Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis. PLoS ONE. 2018;13:e0201744 pubmed publisher |
Wilden A, Molina J, Feuerborn M, Boyle D, Lee S. Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition. Biochim Biophys Acta Mol Cell Res. 2018;1865:1356-1367 pubmed publisher |
Truschel S, Clayton D, Beckel J, Yabes J, Yao Y, Wolf Johnston A, et al. Age-related endolysosome dysfunction in the rat urothelium. PLoS ONE. 2018;13:e0198817 pubmed publisher |
Fensterheim B, YOUNG J, Luan L, Kleinbard R, Stothers C, Patil N, et al. The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. J Immunol. 2018;200:3777-3789 pubmed publisher |
Su L, Li N, Tang H, Lou Z, Chong X, Zhang C, et al. Kupffer cell-derived TNF-α promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells. Cell Death Dis. 2018;9:323 pubmed publisher |
Iacobini C, Blasetti Fantauzzi C, Bedini R, Pecci R, Bartolazzi A, Amadio B, et al. Galectin-3 is essential for proper bone cell differentiation and activity, bone remodeling and biomechanical competence in mice. Metabolism. 2018;83:149-158 pubmed publisher |
Lietman C, Wu B, Lechner S, Shinar A, Sehgal M, Rossomacha E, et al. Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. JCI Insight. 2018;3: pubmed publisher |
Batoon L, Millard S, Wullschleger M, Preda C, Wu A, Kaur S, et al. CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials. 2019;196:51-66 pubmed publisher |
Moon H, Donahue L, Choi E, Scumpia P, Lowry W, Grenier J, et al. Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure. Cell Stem Cell. 2017;21:665-678.e6 pubmed publisher |
Potula H, Richer L, Werts C, Gomes Solecki M. Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells. PLoS Negl Trop Dis. 2017;11:e0005870 pubmed publisher |
Yuan H, Jiang W, von Roemeling C, Qie Y, Liu X, Chen Y, et al. Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy. Nat Nanotechnol. 2017;12:763-769 pubmed publisher |
Chung K, Chatzigeorgiou A, Economopoulou M, Garcia Martin R, Alexaki V, Mitroulis I, et al. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity. Nat Immunol. 2017;18:654-664 pubmed publisher |
Wang W, Xu M, Cai Y, Zhou Z, Cao H, Mukhopadhyay P, et al. Inflammation is independent of steatosis in a murine model of steatohepatitis. Hepatology. 2017;66:108-123 pubmed publisher |
Kondo H, Maksimova N, Otomo T, Kato H, Imai A, Asano Y, et al. Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. Hum Mol Genet. 2017;26:173-183 pubmed publisher |
Demonbreun A, Allen M, Warner J, Barefield D, Krishnan S, Swanson K, et al. Enhanced Muscular Dystrophy from Loss of Dysferlin Is Accompanied by Impaired Annexin A6 Translocation after Sarcolemmal Disruption. Am J Pathol. 2016;186:1610-22 pubmed publisher |
Mareninova O, Sendler M, Malla S, Yakubov I, French S, Tokhtaeva E, et al. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 2015;1:678-694 pubmed |
Zhang H, Lu H, Xiang L, Bullen J, Zhang C, Samanta D, et al. HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells. Proc Natl Acad Sci U S A. 2015;112:E6215-23 pubmed publisher |
Gurda B, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, et al. Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII. Mol Ther. 2016;24:206-216 pubmed publisher |
Ge X, Pettan Brewer C, Morton J, Carter K, Fatemi S, Rabinovitch P, et al. Mitochondrial catalase suppresses naturally occurring lung cancer in old mice. Pathobiol Aging Age Relat Dis. 2015;5:28776 pubmed publisher |
Merches K, Khairnar V, Knuschke T, Shaabani N, Honke N, Duhan V, et al. Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection. Cell Physiol Biochem. 2015;36:2379-92 pubmed publisher |
Saleh M, McMaster W, Wu J, Norlander A, Funt S, Thabet S, et al. Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. J Clin Invest. 2015;125:1189-202 pubmed publisher |
NISHIWAKI S, Nakayama T, Murata M, Nishida T, Terakura S, Saito S, et al. Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions. PLoS ONE. 2014;9:e96252 pubmed publisher |
Kwon H, Won Y, Park O, Chang B, Duryee M, Thiele G, et al. Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice. Hepatology. 2014;60:146-57 pubmed publisher |
Oh J, Lee H, Ko A, Ko J, Kim M, Wee W. Analysis of macrophage phenotype in rejected corneal allografts. Invest Ophthalmol Vis Sci. 2013;54:7779-84 pubmed publisher |
Phieler J, Chung K, Chatzigeorgiou A, Klotzsche von Ameln A, Garcia Martin R, Sprott D, et al. The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance. J Immunol. 2013;191:4367-74 pubmed publisher |
Xiao C, Wang R, Lahusen T, Park O, Bertola A, Maruyama T, et al. Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice. J Biol Chem. 2012;287:41903-13 pubmed publisher |
Karasawa F, Shiota A, Goso Y, Kobayashi M, Sato Y, Masumoto J, et al. Essential role of gastric gland mucin in preventing gastric cancer in mice. J Clin Invest. 2012;122:923-34 pubmed publisher |
Ouvrier A, Alves G, Damon Soubeyrand C, Marceau G, Cadet R, Janny L, et al. Dietary cholesterol-induced post-testicular infertility. PLoS ONE. 2011;6:e26966 pubmed publisher |
Gonzalez J, Dong Z, Romero R, Girardi G. Cervical remodeling/ripening at term and preterm delivery: the same mechanism initiated by different mediators and different effector cells. PLoS ONE. 2011;6:e26877 pubmed publisher |
Harusato A, Naito Y, Takagi T, Uchiyama K, Mizushima K, Hirai Y, et al. Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency. Free Radic Res. 2011;45:717-27 pubmed publisher |
Ramirez N, Zhang Z, Madamanchi A, Boyd K, O Rear L, Nashabi A, et al. The ???? integrin is a metastasis suppressor in mouse models and human cancer. J Clin Invest. 2011;121:226-37 pubmed publisher |
Abrahamson E, Ikonomovic M, Dixon C, DeKosky S. Simvastatin therapy prevents brain trauma-induced increases in beta-amyloid peptide levels. Ann Neurol. 2009;66:407-14 pubmed publisher |
Jin Y, Arita M, Zhang Q, Saban D, Chauhan S, Chiang N, et al. Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators. Invest Ophthalmol Vis Sci. 2009;50:4743-52 pubmed publisher |
Jaruga B, Hong F, Kim W, Sun R, Fan S, Gao B. Chronic alcohol consumption accelerates liver injury in T cell-mediated hepatitis: alcohol disregulation of NF-kappaB and STAT3 signaling pathways. Am J Physiol Gastrointest Liver Physiol. 2004;287:G471-9 pubmed |
