Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:1000; loading ...; fig s4a
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| Toyoda Y, Takada T, Umezawa M, Tomura F, Yamanashi Y, Takeda K, et al. Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe-mediated steatosis prevention and recovery. FASEB Bioadv. 2019;1:283-295 pubmed publisher
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| Na Y, Jung D, Song J, Park J, Seok S. Pyruvate dehydrogenase kinase is a negative regulator of interleukin-10 production in macrophages. J Mol Cell Biol. 2020;: pubmed publisher
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| Toyoda Y, Takada T, Yamanashi Y, Suzuki H. Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet. Lipids Health Dis. 2019;18:234 pubmed publisher
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| Jebessa Z, Shanmukha Kumar D, Dewenter M, Lehmann L, Xu C, Schreiter F, et al. The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4. Nat Metab. 2019;1:1157-1167 pubmed publisher
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| Lu H, Lu Y, Xie Y, Qiu S, Li X, Fan Z. Rational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma. JCI Insight. 2019;4: pubmed publisher
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| Jiang H, Jin J, Duan Y, Xie Z, Li Y, Gao A, et al. Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation. Diabetes. 2019;68:2197-2209 pubmed publisher
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| Li J, Zhu X, Wang H, Lee C, Chen S, Qian Y, et al. Akt1-mediated CPR cooling protection targets regulators of metabolism, inflammation and contractile function in mouse cardiac arrest. PLoS ONE. 2019;14:e0220604 pubmed publisher
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| Yamamoto H, Yamanashi Y, Takada T, Mu S, Tanaka Y, Komine T, et al. Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice. Mol Pharmacol. 2019;96:47-55 pubmed publisher
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| Thapa D, Zhang M, Manning J, Guimaraes D, Stoner M, Lai Y, et al. Loss of GCN5L1 in cardiac cells limits mitochondrial respiratory capacity under hyperglycemic conditions. Physiol Rep. 2019;7:e14054 pubmed publisher
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| Zhong W, Xu M, Li C, Zhu B, Cao X, Li D, et al. ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells. Cell Rep. 2019;26:2166-2177.e9 pubmed publisher
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| Meng Z, Gwag T, Sui Y, Park S, Zhou X, Zhou C. The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling. JCI Insight. 2019;4: pubmed publisher
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| Zhuang Y, Ly R, Frazier C, Yu J, Qin S, Fan X, et al. The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer. Cancer Metab. 2019;7:1 pubmed publisher
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| Ontawong A, Duangjai A, Muanprasat C, Pasachan T, Pongchaidecha A, Amornlerdpison D, et al. Lipid-lowering effects of Coffea arabica pulp aqueous extract in Caco-2 cells and hypercholesterolemic rats. Phytomedicine. 2019;52:187-197 pubmed publisher
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| Kwong J, Huo J, Bround M, Boyer J, Schwanekamp J, Ghazal N, et al. The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle. JCI Insight. 2018;3: pubmed publisher
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| Deng Y, Deng Z, Hao H, Wu X, Gao H, Tang S, et al. MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4. Exp Cell Res. 2018;373:171-179 pubmed publisher
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| Thapa D, Wu K, Stoner M, Xie B, Zhang M, Manning J, et al. The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA. J Biol Chem. 2018;293:17676-17684 pubmed publisher
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| Lemecha M, Morino K, Imamura T, Iwasaki H, Ohashi N, Ida S, et al. MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes. Sci Rep. 2018;8:15096 pubmed publisher
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| Gao Y, Zhou Z, Ren T, Kim S, He Y, Seo W, et al. Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids. Gut. 2019;68:1311-1322 pubmed publisher
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| Ahn S, Jun D, Jang K, Lee B, Shin K. Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease. Korean J Intern Med. 2019;34:777-784 pubmed publisher
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| Menk A, Scharping N, Moreci R, Zeng X, Guy C, Salvatore S, et al. Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions. Cell Rep. 2018;22:1509-1521 pubmed publisher
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| Xu S, Liu C, Xu W, Huang L, Zhao J, Zhao S. Butyrate induces apoptosis by activating PDC and inhibiting complex I through SIRT3 inactivation. Signal Transduct Target Ther. 2017;2:16035 pubmed publisher
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| Liu X, Zuo R, Bao Y, Qu X, Sun K, Ying H. Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts. Sci Rep. 2017;7:8474 pubmed publisher
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| Gorga A, Rindone G, Regueira M, Pellizzari E, Camberos M, Cigorraga S, et al. PPARγ activation regulates lipid droplet formation and lactate production in rat Sertoli cells. Cell Tissue Res. 2017;369:611-624 pubmed publisher
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| Bhosale G, Sharpe J, Koh A, Kouli A, Szabadkai G, Duchen M. Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics. Biochim Biophys Acta Mol Cell Res. 2017;1864:1009-1017 pubmed publisher
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| Jun J, Devera R, Unnikrishnan D, Shin M, Bevans Fonti S, Yao Q, et al. Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis. J Mol Med (Berl). 2017;95:287-297 pubmed publisher
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| Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed publisher
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| Soayfane Z, Tercé F, Cantiello M, Robenek H, Nauze M, Bézirard V, et al. Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane. Nutr Metab (Lond). 2016;13:48 pubmed publisher
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| Lu H, Li X, Lu Y, Qiu S, Fan Z. ASCT2 (SLC1A5) is an EGFR-associated protein that can be co-targeted by cetuximab to sensitize cancer cells to ROS-induced apoptosis. Cancer Lett. 2016;381:23-30 pubmed publisher
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| Rossi S, Windschüttl S, Matzkin M, Rey Ares V, Terradas C, Ponzio R, et al. Reactive oxygen species (ROS) production triggered by prostaglandin D2 (PGD2) regulates lactate dehydrogenase (LDH) expression/activity in TM4 Sertoli cells. Mol Cell Endocrinol. 2016;434:154-65 pubmed publisher
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| Kawase A, Hata S, Takagi M, Iwaki M. Pravastatin Modulate Niemann-Pick C1-Like 1 and ATP-Binding Cassette G5 and G8 to Influence Intestinal Cholesterol Absorption. J Pharm Pharm Sci. 2015;18:765-72 pubmed
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| Regueira M, Artagaveytia S, Galardo M, Pellizzari E, Cigorraga S, Meroni S, et al. Novel molecular mechanisms involved in hormonal regulation of lactate production in Sertoli cells. Reproduction. 2015;150:311-21 pubmed publisher
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| Zuo R, Gu X, Qi Q, Wang T, Zhao X, Liu J, et al. Warburg-like Glycolysis and Lactate Shuttle in Mouse Decidua during Early Pregnancy. J Biol Chem. 2015;290:21280-91 pubmed publisher
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| Hagopian K, Tomilov A, Kim K, Cortopassi G, Ramsey J. Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins. PLoS ONE. 2015;10:e0124204 pubmed publisher
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| Sui Y, Helsley R, Park S, Song X, Liu Z, Zhou C. Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia. Mol Endocrinol. 2015;29:765-76 pubmed publisher
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| Llorente Folch I, Rueda C, Pardo B, Szabadkai G, Duchen M, Satrustegui J. The regulation of neuronal mitochondrial metabolism by calcium. J Physiol. 2015;593:3447-62 pubmed publisher
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| Takada T, Yamanashi Y, Konishi K, Yamamoto T, Toyoda Y, Masuo Y, et al. NPC1L1 is a key regulator of intestinal vitamin K absorption and a modulator of warfarin therapy. Sci Transl Med. 2015;7:275ra23 pubmed publisher
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| Ho N, Coomber B. Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells. Exp Cell Res. 2015;331:73-81 pubmed publisher
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| Delaney L, Ho N, Morrison J, Farias N, Mosser D, Coomber B. Dichloroacetate affects proliferation but not survival of human colorectal cancer cells. Apoptosis. 2015;20:63-74 pubmed publisher
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