Niemann-Pick type C1 Like-1 Antibody - BSA Free | Novus Biologicals NB400-127 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Niemann-Pick type C1 Like-1 Antibody - BSA Free

catalog :

NB400-127

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 20

Reference
Lee C, Kwak S, Han J, Shin J, Yoo B, Lee Y, et al. Repositioning of ezetimibe for the treatment of idiopathic pulmonary fibrosis. Eur Respir J. 2024;63: pubmed publisher
Zhang Z, Qin S, Chen Y, Zhou L, Yang M, Tang Y, et al. Inhibition of NPC1L1 disrupts adaptive responses of drug-tolerant persister cells to chemotherapy. EMBO Mol Med. 2022;14:e14903 pubmed publisher
Haghikia A, Zimmermann F, Schumann P, Jasina A, Roessler J, Schmidt D, et al. Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism. Eur Heart J. 2022;43:518-533 pubmed publisher
Sugimoto S, Kobayashi E, Fujii M, Ohta Y, Arai K, Matano M, et al. An organoid-based organ-repurposing approach to treat short bowel syndrome. Nature. 2021;592:99-104 pubmed publisher
Zimmermann F, Roessler J, Schmidt D, Jasina A, Schumann P, Gast M, et al. Impact of the Gut Microbiota on Atorvastatin Mediated Effects on Blood Lipids. J Clin Med. 2020;9: pubmed publisher
Sosunov A, Wu X, McGovern R, Mikell C, McKhann G, Goldman J. Abnormal mitosis in reactive astrocytes. Acta Neuropathol Commun. 2020;8:47 pubmed publisher
Wang Y, Stear J, Swain A, Xu X, Bryce N, Carnell M, et al. Drug Targeting the Actin Cytoskeleton Potentiates the Cytotoxicity of Low Dose Vincristine by Abrogating Actin-Mediated Repair of Spindle Defects. Mol Cancer Res. 2020;18:1074-1087 pubmed publisher
Gemble S, Simon A, Pennetier C, Dumont M, Hervé S, Meitinger F, et al. Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity. Curr Biol. 2019;29:3072-3080.e5 pubmed publisher
Hueschen C, Galstyan V, Amouzgar M, Phillips R, Dumont S. Microtubule End-Clustering Maintains a Steady-State Spindle Shape. Curr Biol. 2019;29:700-708.e5 pubmed publisher
Nihei W, Nagafuku M, Hayamizu H, Odagiri Y, Tamura Y, Kikuchi Y, et al. NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains. J Lipid Res. 2018;59:2181-2187 pubmed publisher
Hueschen C, Kenny S, Xu K, Dumont S. NuMA recruits dynein activity to microtubule minus-ends at mitosis. elife. 2017;6: pubmed publisher
di Pietro F, Valon L, Li Y, Goïame R, Genovesio A, Morin X. An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z ? as an Essential Regulator of Spindle Orientation. Curr Biol. 2017;27:2452-2464.e8 pubmed publisher
Elting M, Prakash M, Udy D, Dumont S. Mapping Load-Bearing in the Mammalian Spindle Reveals Local Kinetochore Fiber Anchorage that Provides Mechanical Isolation and Redundancy. Curr Biol. 2017;27:2112-2122.e5 pubmed publisher
Decarreau J, Wagenbach M, Lynch E, Halpern A, Vaughan J, KOLLMAN J, et al. The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation. Nat Cell Biol. 2017;19:384-390 pubmed publisher
Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, et al. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep. 2016;6:22 pubmed publisher
Feng D, Zou J, Zhang S, Li X, Lu M. Hypocholesterolemic Activity of Curcumin Is Mediated by Down-regulating the Expression of Niemann-Pick C1-like 1 in Hamsters. J Agric Food Chem. 2017;65:276-280 pubmed publisher
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product information

master code :

NB400-127

SKU :

NB400-127

product name :

Niemann-Pick type C1 Like-1 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Niemann-Pick type C1 Like-1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Niemann-Pick type C1 Like-1. This antibody reacts with human,mouse,porcine,rat. The Niemann-Pick type C1 Like-1 Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Electron Microscopy,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry.

target :

Niemann-Pick type C1 Like-1

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

A synthetic peptide made to an internal region of rat Niemann-Pick type C1 Like-1 (between residues 1000-1100). [UniProt# Q6T3U3]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Porcine,Rat

theoretical molecular weight :

140 kDa

gene symbol :

NPC1L1

applications :

IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Electron Microscopy,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry

USD :

409 USD

alt names :

Niemann-Pick C1-like protein 1, NPC1 (Niemann-Pick disease, type C1, gene)-like 1, NPC11L1

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage