| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; human; 1:100; fig 3
- western blot; human; 1:1000; fig 3
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| Liebscher G, Vujić N, Schreiber R, Heine M, Krebiehl C, Duta Mare M, et al. The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue. Mol Metab. 2023;71:101705 pubmed publisher |
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| Emami N, Cauble R, Dhamad A, Greene E, Coy C, Velleman S, et al. Hypoxia further exacerbates woody breast myopathy in broilers via alteration of satellite cell fate. Poult Sci. 2021;100:101167 pubmed publisher |
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| Miller H, Gorthi A, Bassani N, Lawrence L, Iskra B, Bishop A. Reconstruction of Ewing Sarcoma Developmental Context from Mass-Scale Transcriptomics Reveals Characteristics of EWSR1-FLI1 Permissibility. Cancers (Basel). 2020;12: pubmed publisher |
| Han Y, Lee Y, Jang Y, Kim H, Seo H, Jung T, et al. Aspirin Improves Nonalcoholic Fatty Liver Disease and Atherosclerosis through Regulation of the PPARδ-AMPK-PGC-1α Pathway in Dyslipidemic Conditions. Biomed Res Int. 2020;2020:7806860 pubmed publisher |
| Cai M, Dunn C, Chen W, Kochupurakkal B, Nguyen H, Moreau L, et al. Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection. Cell Rep. 2020;30:2402-2415.e5 pubmed publisher |
| Yang Y, Guo T, Liu R, Ke H, Xu W, Zhao S, et al. FANCL gene mutations in premature ovarian insufficiency. Hum Mutat. 2020;41:1033-1041 pubmed publisher |
| Ardeljan D, Steranka J, Liu C, Li Z, Taylor M, Payer L, et al. Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication. Nat Struct Mol Biol. 2020;27:168-178 pubmed publisher |
| Li N, Wang J, Wallace S, Chen J, Zhou J, D Andrea A. Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair. Nucleic Acids Res. 2020;48:3014-3028 pubmed publisher |
| Iizuka Y, Chiba K, Kim H, Hirako S, Wada M, Matsumoto A. Impact of discontinuation of fish oil after pioglitazone-fish oil combination therapy in diabetic KK mice. J Nutr Biochem. 2020;76:108265 pubmed publisher |
| Achuthankutty D, Thakur R, Haahr P, Hoffmann S, Drainas A, Bizard A, et al. Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability. J Cell Biol. 2019;218:3943-3953 pubmed publisher |
| Mason J, Chan Y, Weichselbaum R, Bishop D. Non-enzymatic roles of human RAD51 at stalled replication forks. Nat Commun. 2019;10:4410 pubmed publisher |
| Sonneville R, Bhowmick R, Hoffmann S, Mailand N, Hickson I, Labib K. TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication. elife. 2019;8: pubmed publisher |
| Chang E, Tsai S, Aristizabal M, Wells J, Coulombe Y, Busatto F, et al. MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription-replication conflicts. Nat Commun. 2019;10:4265 pubmed publisher |
| Bi J, Areecheewakul S, Li Y, Yang S, Zhang Y, Ebeid K, et al. MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy. Gynecol Oncol. 2019;155:349-358 pubmed publisher |
| Fragkos M, Barra V, Egger T, Bordignon B, Lemaçon D, Naim V, et al. Dicer prevents genome instability in response to replication stress. Oncotarget. 2019;10:4407-4423 pubmed publisher |
| Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;11:e9982 pubmed publisher |
| Pladevall Morera D, Munk S, Ingham A, Garribba L, Albers E, Liu Y, et al. Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability. Nucleic Acids Res. 2019;47:8004-8018 pubmed publisher |
| Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;: pubmed publisher |
| Paquin K, Mamrak N, Garzon J, Cantres Velez J, Azzinaro P, Vuono E, et al. FANCD2 binding to H4K20me2 via a methyl-binding domain is essential for efficient DNA crosslink repair. Mol Cell Biol. 2019;: pubmed publisher |
| Huang J, Zhang J, Bellani M, Pokharel D, Gichimu J, James R, et al. Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2. Cell Rep. 2019;27:1794-1808.e5 pubmed publisher |
| Gang X, Xuan L, Zhao X, Lv Y, Li F, Wang Y, et al. Speckle-type POZ protein suppresses lipid accumulation and prostate cancer growth by stabilizing fatty acid synthase. Prostate. 2019;79:864-871 pubmed publisher |
| Andreev V, Hristova R, Asparuhova M, Danovski G, Stoynov S, Gospodinov A. Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair. DNA Repair (Amst). 2019;74:38-50 pubmed publisher |
| Ramanagoudr Bhojappa R, Carrington B, Ramaswami M, Bishop K, Robbins G, Jones M, et al. Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility. PLoS Genet. 2018;14:e1007821 pubmed publisher |
| Li M, Vera N, Yang Y, Zhang B, Ni W, Ziso Qejvanaj E, et al. Adipocyte OGT governs diet-induced hyperphagia and obesity. Nat Commun. 2018;9:5103 pubmed publisher |
| Balcerek J, Jiang J, Li Y, Jiang Q, Holdreith N, Singh B, et al. Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia. Nat Commun. 2018;9:3915 pubmed publisher |
| Andrews A, McCartney H, Errington T, D Andrea A, Macara I. A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links. Nat Commun. 2018;9:2592 pubmed publisher |
| Higgs M, Sato K, Reynolds J, Begum S, Bayley R, Goula A, et al. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Mol Cell. 2018;71:25-41.e6 pubmed publisher |
| Tremblay C, Huang F, Levesque G, Carreau M. Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity. BMC Res Notes. 2018;11:138 pubmed publisher |
| Kim J, Sturgill D, Sebastian R, Khurana S, Tran A, Edwards G, et al. Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. Mol Cell. 2018;69:36-47.e7 pubmed publisher |
| Asur R, Kimble D, Lach F, Jung M, Donovan F, Kamat A, et al. Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype. Mol Genet Genomic Med. 2017;: pubmed publisher |
| Hooks K, Audoux J, Fazli H, Lesjean S, Ernault T, Senant N, et al. New insights into diagnosis and therapeutic options for proliferative hepatoblastoma. Hepatology. 2017;: pubmed publisher |
| Vierra D, Garzon J, Rego M, Adroved M, Mauro M, Howlett N. Modulation of the Fanconi anemia pathway via chemically induced changes in chromatin structure. Oncotarget. 2017;8:76443-76457 pubmed publisher |
| Sakasai R, Isono M, Wakasugi M, Hashimoto M, Sunatani Y, Matsui T, et al. Aquarius is required for proper CtIP expression and homologous recombination repair. Sci Rep. 2017;7:13808 pubmed publisher |
| Porro A, Berti M, Pizzolato J, Bologna S, Kaden S, Saxer A, et al. FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2. Nat Commun. 2017;8:1073 pubmed publisher |
| Chang E, Novoa C, Aristizabal M, Coulombe Y, Segovia R, Chaturvedi R, et al. RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability. J Cell Biol. 2017;216:3991-4005 pubmed publisher |
| Preiss M, Cournoyer E, Paquin K, Vuono E, Belanger K, Walsh E, et al. Tuning the Multifunctionality of Iron Oxide Nanoparticles Using Self-Assembled Mixed Lipid Layers. Bioconjug Chem. 2017;28:2729-2736 pubmed publisher |
| Moriel Carretero M, Ovejero S, Gérus Durand M, Vryzas D, Constantinou A. Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors. J Cell Biol. 2017;216:4007-4026 pubmed publisher |
| Bou Samra E, Buhagiar Labarchède G, Machon C, Guitton J, Onclercq Delic R, Green M, et al. A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival. Nat Commun. 2017;8:693 pubmed publisher |
| Feng W, Jasin M. BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination. Nat Commun. 2017;8:525 pubmed publisher |
| Walz J, Saha J, Arora A, Khammanivong A, O Sullivan M, Dickerson E. Fatty acid synthase as a potential therapeutic target in feline oral squamous cell carcinoma. Vet Comp Oncol. 2018;16:E99-E108 pubmed publisher |
| Wilkes D, Sailer V, Xue H, Cheng H, Collins C, Gleave M, et al. A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents. Cold Spring Harb Mol Case Stud. 2017;3: pubmed publisher |
| Tacconi E, Lai X, Folio C, Porru M, Zonderland G, Badie S, et al. BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity. EMBO Mol Med. 2017;9:1398-1414 pubmed publisher |
| Marchesini M, Ogoti Y, Fiorini E, Aktaş Samur A, Nezi L, D Anca M, et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017;32:88-100.e6 pubmed publisher |
| Niraj J, Caron M, Drapeau K, Bérubé S, Guitton Sert L, Coulombe Y, et al. The identification of FANCD2 DNA binding domains reveals nuclear localization sequences. Nucleic Acids Res. 2017;45:8341-8357 pubmed publisher |
| Jiang J, Bellani M, Li L, Wang P, Seidman M, Wang Y. Arsenite Binds to the RING Finger Domain of FANCL E3 Ubiquitin Ligase and Inhibits DNA Interstrand Crosslink Repair. ACS Chem Biol. 2017;12:1858-1866 pubmed publisher |
| Bharathan S, Nandy K, Palani D, Janet A N, Natarajan K, George B, et al. Generation of an induced pluripotent stem cell line that mimics the disease phenotypes from a patient with Fanconi anemia by conditional complementation. Stem Cell Res. 2017;20:54-57 pubmed publisher |
| Spriggs C, Laimins L. FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication. MBio. 2017;8: pubmed publisher |
| Chun M, Choi H, Jun D, Kim S, Kim Y, Kim S, et al. Fanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolism. FEBS Open Bio. 2017;7:284-292 pubmed publisher |
| Lv Z, Rickman K, Yuan L, Williams K, Selvam S, Woosley A, et al. S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Mol Cell. 2017;65:699-714.e6 pubmed publisher |
| Johnson S, Cruz C, Greifenberg A, Dust S, Stover D, Chi D, et al. CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer. Cell Rep. 2016;17:2367-2381 pubmed publisher |
| Vuono E, Mukherjee A, Vierra D, Adroved M, Hodson C, Deans A, et al. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep. 2016;6:36439 pubmed publisher |
| Bezine E, Malaisé Y, Loeuillet A, Chevalier M, Boutet Robinet E, Salles B, et al. Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms. Sci Rep. 2016;6:36022 pubmed publisher |
| Alavattam K, Kato Y, Sin H, Maezawa S, Kowalski I, Zhang F, et al. Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications. Cell Rep. 2016;17:1141-1157 pubmed publisher |
| Sato K, Shimomuki M, Katsuki Y, Takahashi D, Kobayashi W, Ishiai M, et al. FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end. Nucleic Acids Res. 2016;44:10758-10771 pubmed |
| Park S, Sung Y, Jang S, Nho K, Choi G, Kim H. The Korean herbal medicine, Do In Seung Gi-Tang, attenuates atherosclerosis via AMPK in high-fat diet-induced ApoE(-/-) mice. BMC Complement Altern Med. 2016;16:352 pubmed publisher |
| Fu C, Begum K, Jordan P, He Y, Overbeek P. Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS ONE. 2016;11:e0159800 pubmed publisher |
| Chen C, Chuang W, Lin A, Tsai C, Huang C, Chen Y, et al. Andrographolide inhibits adipogenesis of 3T3-L1 cells by suppressing C/EBP? expression and activation. Toxicol Appl Pharmacol. 2016;307:115-122 pubmed publisher |
| Root H, Larsen A, Komosa M, Al Azri F, Li R, Bazett Jones D, et al. FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway. Hum Mol Genet. 2016;25:3255-3268 pubmed publisher |
| Chun M, Hwang S, Kim H, Goh S, Kim S, Lee C. Aurora A kinase is required for activation of the Fanconi anemia/BRCA pathway upon DNA damage. FEBS Open Bio. 2016;6:782-90 pubmed publisher |
| Michl J, Zimmer J, Buffa F, McDermott U, Tarsounas M. FANCD2 limits replication stress and genome instability in cells lacking BRCA2. Nat Struct Mol Biol. 2016;23:755-757 pubmed publisher |
| Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher |
| Maeda J, Froning C, Brents C, Rose B, Thamm D, Kato T. Intrinsic Radiosensitivity and Cellular Characterization of 27 Canine Cancer Cell Lines. PLoS ONE. 2016;11:e0156689 pubmed publisher |
| Wang F, Gao C, Lu J, Tatetsu H, Williams D, Müller L, et al. Leukemic survival factor SALL4 contributes to defective DNA damage repair. Oncogene. 2016;35:6087-6095 pubmed publisher |
| Panneerselvam J, Wang H, Zhang J, Che R, Yu H, Fei P. BLM promotes the activation of Fanconi Anemia signaling pathway. Oncotarget. 2016;7:32351-61 pubmed publisher |
| Gang X, Yang Y, Zhong J, Jiang K, Pan Y, Karnes R, et al. P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth. Oncotarget. 2016;7:15135-49 pubmed publisher |
| Minocherhomji S, Ying S, Bjerregaard V, Bursomanno S, Aleliunaite A, Wu W, et al. Replication stress activates DNA repair synthesis in mitosis. Nature. 2015;528:286-90 pubmed publisher |
| Bouffard F, Plourde K, Bélanger S, Ouellette G, Labrie Y, Durocher F. Analysis of a FANCE Splice Isoform in Regard to DNA Repair. J Mol Biol. 2015;427:3056-73 pubmed publisher |
| Stoepker C, Ameziane N, van der Lelij P, Kooi I, Oostra A, Rooimans M, et al. Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer. Cancer Res. 2015;75:3543-53 pubmed publisher |
| Rickman K, Lach F, Abhyankar A, Donovan F, Sanborn E, Kennedy J, et al. Deficiency of UBE2T, the E2Â Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia. Cell Rep. 2015;12:35-41 pubmed publisher |
| Zhu J, Su F, Mukherjee S, Mori E, Hu B, Asaithamby A. FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle. 2015;14:1809-22 pubmed publisher |
| Zhang T, Wilson A, Mahmood Ali A, Namekawa S, Andreassen P, Ruhikanta Meetei A, et al. Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress. Stem Cells. 2015;33:2320-30 pubmed publisher |
| Oka Y, Bekker Jensen S, Mailand N. Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway. EMBO J. 2015;34:1385-98 pubmed publisher |
| Kim K, Cho Y, Park B, Lee J, Ro J, Go H, et al. Histological and immunohistochemical markers for progression prediction in transurethrally resected high-grade non-muscle invasive bladder cancer. Int J Clin Exp Pathol. 2015;8:743-50 pubmed |
| Xie J, Kim H, Moreau L, Puhalla S, Garber J, Al Abo M, et al. RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. J Clin Invest. 2015;125:1523-32 pubmed publisher |
| Brem R, Zhang X, Xu Y, Karran P. UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions. J Photochem Photobiol B. 2015;145:1-10 pubmed publisher |
| Aarts M, Bajrami I, Herrera Abreu M, Elliott R, Brough R, Ashworth A, et al. Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways. Mol Cancer Ther. 2015;14:865-76 pubmed publisher |
| Stoepker C, Faramarz A, Rooimans M, van Mil S, Balk J, Velleuer E, et al. DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity. DNA Repair (Amst). 2015;26:54-64 pubmed publisher |
| Bursomanno S, Beli P, Khan A, Minocherhomji S, Wagner S, Bekker Jensen S, et al. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. DNA Repair (Amst). 2015;25:84-96 pubmed publisher |
| Zhu B, Yan K, Li L, Lin M, Zhang S, He Q, et al. K63-linked ubiquitination of FANCG is required for its association with the Rap80-BRCA1 complex to modulate homologous recombination repair of DNA interstand crosslinks. Oncogene. 2015;34:2867-78 pubmed publisher |
