product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SR-BI Antibody - BSA Free
catalog :
NB400-104
quantity :
0.1 ml (also 0.025 ml)
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
OTI2B3
reactivity :
hamsters, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay, blocking or activating experiments
more info or order :
citations: 101
Published Application/Species/Sample/DilutionReference
  • proximity ligation assay; human; 1:100; fig 4c
Kulkarni N, O Neill A, Dokoshi T, Luo E, Wong G, Gallo R. Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors. J Biol Chem. 2021;297:100828 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Zhu L, Shi J, Luu T, Neuman J, Trefts E, Yu S, et al. Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding. Mol Metab. 2018;8:106-116 pubmed publisher
  • western blot; human; fig 4c
Fung K, Wang C, Nyegaard S, Heit B, Fairn G, Lee W. SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1. Front Physiol. 2017;8:841 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Castella B, Kopecka J, Sciancalepore P, Mandili G, Foglietta M, Mitro N, et al. The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells. Nat Commun. 2017;8:15663 pubmed publisher
  • western blot; hamsters; loading ...; fig 4d
Hirata H, Uto Kondo H, Ogura M, Ayaori M, Shiotani K, Ota A, et al. Xanthohumol, a hop-derived prenylated flavonoid, promotes macrophage reverse cholesterol transport. J Nutr Biochem. 2017;47:29-34 pubmed publisher
  • western blot; human; loading ...
Nelson J, Koenis D, Scheij S, Cook E, Moeton M, Santos A, et al. EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux. Arterioscler Thromb Vasc Biol. 2017;37:423-432 pubmed publisher
  • western blot; mouse; loading ...; fig 9c
Milligan S, Martin G, Landrock D, McIntosh A, Mackie J, Schroeder F, et al. Impact of dietary phytol on lipid metabolism in SCP2/SCPX/L-FABP null mice. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:291-304 pubmed publisher
  • western blot; human; 1:500; fig 3c
Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, et al. Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages. Mol Nutr Food Res. 2017;61: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 8i
Geng S, Chen K, Yuan R, Peng L, Maitra U, Diao N, et al. The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis. Nat Commun. 2016;7:13436 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:4000; loading ...; fig 4c
Julovi S, Xue A, Thanh LE T, Gill A, Bulanadi J, Patel M, et al. Apolipoprotein A-II Plus Lipid Emulsion Enhance Cell Growth via SR-B1 and Target Pancreatic Cancer In Vitro and In Vivo. PLoS ONE. 2016;11:e0151475 pubmed publisher
  • blocking or activating experiments; human; fig 2
  • western blot; human; fig 2
Cheng J, Li J, Huang M, Ma L, Wu Z, Jiang C, et al. CD36 is a co-receptor for hepatitis C virus E1 protein attachment. Sci Rep. 2016;6:21808 pubmed publisher
  • western blot; human; fig 5
Mysore R, Zhou Y, Sädevirta S, Savolainen Peltonen H, Nidhina Haridas P, Soronen J, et al. MicroRNA-192* impairs adipocyte triglyceride storage. Biochim Biophys Acta. 2016;1861:342-51 pubmed publisher
Chi H, Qu B, Prawira A, Richardt T, Maurer L, Hu J, et al. An hepatitis B and D virus infection model using human pluripotent stem cell-derived hepatocytes. EMBO Rep. 2024;25:4311-4336 pubmed publisher
Pewkliang Y, Thongsri P, Suthivanich P, Thongbaiphet N, Keatkla J, Pasomsub E, et al. Immortalized hepatocyte-like cells: A competent hepatocyte model for studying clinical HCV isolate infection. PLoS ONE. 2024;19:e0303265 pubmed publisher
Bassila C, Kluck G, Thyagarajan N, Chathely K, Gonzalez L, Trigatti B. Ligand-dependent interactions between SR-B1 and S1PR1 in macrophages and atherosclerotic plaques. J Lipid Res. 2024;65:100541 pubmed publisher
Hu S, Zhu Y, Zhao X, Li R, Shao G, Gong D, et al. Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice. Dev Cell. 2023;58:2326-2337.e5 pubmed publisher
Chen Q, Wang L, Song H, Xing W, Shi J, Li Y, et al. Deficiency of SR-B1 reduced the tumor load of colitis-induced or APCmin /+ -induced colorectal cancer. Cancer Med. 2023;12:19744-19757 pubmed publisher
Su J, Hong Y, Han C, Yu J, Guan X, Zhu Y, et al. Dual action of macrophage miR-204 confines cyclosporine A-induced atherosclerosis. Br J Pharmacol. 2023;: pubmed publisher
Thapa K, Kadiri J, Saukkonen K, Pennanen I, Ghimire B, Cai M, et al. Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver. elife. 2023;12: pubmed publisher
Wolfisberg R, Holmbeck K, Billerbeck E, Thorselius C, Batista M, Fahn xf8 e U, et al. Molecular Determinants of Mouse Adaptation of Rat Hepacivirus. J Virol. 2023;97:e0181222 pubmed publisher
Lyu J, Imachi H, Fukunaga K, Sato S, Kobayashi T, Saheki T, et al. Exendin-4 Increases Scavenger Receptor Class BI Expression via Activation of AMPK/FoxO1 in Human Vascular Endothelial Cells. Curr Issues Mol Biol. 2022;44:5474-5484 pubmed publisher
Frey K, Goetze S, Rohrer L, von Eckardstein A, Wollscheid B. Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions. Int J Mol Sci. 2022;23: pubmed publisher
Acosta Guti xe9 rrez S, Matias D, Avila Olias M, Gouveia V, Scarpa E, Forth J, et al. A Multiscale Study of Phosphorylcholine Driven Cellular Phenotypic Targeting. ACS Cent Sci. 2022;8:891-904 pubmed publisher
Wolfisberg R, Thorselius C, Salinas E, Elrod E, Trivedi S, Nielsen L, et al. Neutralization and receptor use of infectious culture-derived rat hepacivirus as a model for HCV. Hepatology. 2022;76:1506-1519 pubmed publisher
Li L, Zhong S, Li R, Liang N, Zhang L, Xia S, et al. Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression. JCI Insight. 2022;7: pubmed publisher
Yano H, Fujiwara Y, Horlad H, Pan C, Kai K, Niino D, et al. Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy. Cancer Sci. 2022;113:2129-2143 pubmed publisher
Li Q, Liu X, Zhang X, Du Y, Chen G, Xiang P, et al. Terpene Lactucopicrin Limits Macrophage Foam Cell Formation by a Reduction of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Lipid Rafts. Mol Nutr Food Res. 2022;66:e2100905 pubmed publisher
Nyandwi J, Ko Y, Jin H, Yun S, Park S, Kim H. Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice. Biomolecules. 2021;11: pubmed publisher
Haberl E, Pohl R, Rein Fischboeck L, Höring M, Krautbauer S, Liebisch G, et al. Accumulation of cholesterol, triglycerides and ceramides in hepatocellular carcinomas of diethylnitrosamine injected mice. Lipids Health Dis. 2021;20:135 pubmed publisher
Raith M, Kauffman S, Asoudeh M, Buczek J, Kang N, Mays J, et al. Elongated PEO-based nanoparticles bind the high-density lipoprotein (HDL) receptor scavenger receptor class B I (SR-BI). J Control Release. 2021;337:448-457 pubmed publisher
Zapatero Belinchón F, Ötjengerdes R, Sheldon J, Schulte B, Carriquí Madroñal B, Brogden G, et al. Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity. Cells. 2021;10: pubmed publisher
Cabodevilla A, Tang S, Lee S, Mullick A, Aleman J, Hussain M, et al. Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation. J Clin Invest. 2021;131: pubmed publisher
Zhang Z, Zhou Q, Liu R, Liu L, Shen W, Azhar S, et al. The adaptor protein GIPC1 stabilizes the scavenger receptor SR-B1 and increases its cholesterol uptake. J Biol Chem. 2021;296:100616 pubmed publisher
Li X, Lü Q, Qiu Y, do Carmo J, Wang Z, da Silva A, et al. Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure. J Am Heart Assoc. 2021;10:e018298 pubmed publisher
Morton R, Mihna D, Liu Y. The lipid substrate preference of CETP controls the biochemical properties of HDL in fat/cholesterol-fed hamsters. J Lipid Res. 2021;62:100027 pubmed publisher
. E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2021;:ATVBAHA120314156 pubmed publisher
Ma C, Zhang J, Yang S, Hua Y, Su J, Shang Y, et al. Astragalus Flavone Ameliorates Atherosclerosis and Hepatic Steatosis Via Inhibiting Lipid-Disorder and Inflammation in apoE-/- Mice. Front Pharmacol. 2020;11:610550 pubmed publisher
Bhandari S, Li R, Simon Santamaria J, McCourt P, Johansen S, Smedsrød B, et al. Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages. BMC Mol Cell Biol. 2020;21:85 pubmed publisher
Ghaffari S, Jang E, Naderinabi F, Sanwal R, Khosraviani N, Wang C, et al. Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2-SR-BI Axis. Arterioscler Thromb Vasc Biol. 2021;41:200-216 pubmed publisher
Wang D, Hiebl V, Schachner D, Ladurner A, Heiss E, Atanasov A, et al. Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation. Biochem Pharmacol. 2020;177:114022 pubmed publisher
Marshall J, Courage E, Elliott R, Fitzpatrick M, Kim A, Lopez Clavijo A, et al. THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation. PLoS ONE. 2020;15:e0233180 pubmed publisher
Traughber C, Opoku E, Brubaker G, Major J, Lu H, Lorkowski S, et al. Uptake of high-density lipoprotein by scavenger receptor class B type 1 is associated with prostate cancer proliferation and tumor progression in mice. J Biol Chem. 2020;295:8252-8261 pubmed publisher
Mutoh T, Shirai T, Ishii T, Shirota Y, Fujishima F, Takahashi F, et al. Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis. Nat Commun. 2020;11:1253 pubmed publisher
Meng X, Yin J, Yu X, Guo Y. MicroRNA-205-5p Promotes Unstable Atherosclerotic Plaque Formation In Vivo. Cardiovasc Drugs Ther. 2020;34:25-39 pubmed publisher
Ji A, Wang X, Noffsinger V, Jennings D, de Beer M, de Beer F, et al. Serum amyloid A is not incorporated into HDL during HDL biogenesis. J Lipid Res. 2020;61:328-337 pubmed publisher
Huang J, Yin H, Yin P, Jian X, Song S, Luan J, et al. SR-BI Interactome Analysis Reveals a Proviral Role for UGGT1 in Hepatitis C Virus Entry. Front Microbiol. 2019;10:2043 pubmed publisher
Zhang J, Qu C, Li T, Cui W, Wang X, Du J. Phagocytosis mediated by scavenger receptor class BI promotes macrophage transition during skeletal muscle regeneration. J Biol Chem. 2019;294:15672-15685 pubmed publisher
Dolezelova E, Sa I, Prasnicka A, Hroch M, Hyspler R, Ticha A, et al. High soluble endoglin levels regulate cholesterol homeostasis and bile acids turnover in the liver of transgenic mice. Life Sci. 2019;232:116643 pubmed publisher
Roscam Abbing R, Slijepcevic D, Donkers J, Havinga R, Duijst S, Paulusma C, et al. Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice. Hepatology. 2020;71:247-258 pubmed publisher
Gordon J, Noble J, Midha A, Derakhshan F, Wang G, Adomat H, et al. Upregulation of Scavenger receptor B1 is required for steroidogenic and non-steroidogenic cholesterol metabolism in prostate cancer. Cancer Res. 2019;: pubmed publisher
Huang L, Chambliss K, Gao X, Yuhanna I, Behling Kelly E, Bergaya S, et al. SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis. Nature. 2019;569:565-569 pubmed publisher
Wu Z, Li H, Li J, Lv X, Jiang J, Peng Z. Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I. Eur J Pharmacol. 2019;853:111-120 pubmed publisher
Tsuzuki S, Lee S, Kimoto Y, Sugawara T, Manabe Y, Inoue K. A role for scavenger receptor B1 as a captor of specific fatty acids in taste buds of circumvallate papillae. Biomed Res. 2018;39:295-300 pubmed publisher
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018;15:909-912 pubmed publisher
Ghaffari S, Naderi Nabi F, Sugiyama M, Lee W. Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein-Coupled Estrogen Receptor) and SR-BI (Scavenger Receptor Class B Type 1). Arterioscler Thromb Vasc Biol. 2018;38:2283-2294 pubmed publisher
Nishino T, Horie T, Baba O, Sowa N, Hanada R, Kuwabara Y, et al. SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo. Arterioscler Thromb Vasc Biol. 2018;38:2460-2473 pubmed publisher
Cartocci V, Tonini C, Di Pippo T, Vuono F, Schiavi S, Marino M, et al. Prenatal exposure to valproate induces sex-, age-, and tissue-dependent alterations of cholesterol metabolism: Potential implications on autism. J Cell Physiol. 2019;234:4362-4374 pubmed publisher
Cairns R, Fischer A, Blanco Muñoz P, Alvarez Guaita A, Meneses Salas E, Egert A, et al. Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet. PLoS ONE. 2018;13:e0201310 pubmed publisher
Sun Y, Zhang D, Liu X, Li X, Liu F, Yu Y, et al. Endoplasmic Reticulum Stress Affects Lipid Metabolism in Atherosclerosis Via CHOP Activation and Over-Expression of miR-33. Cell Physiol Biochem. 2018;48:1995-2010 pubmed publisher
Sticozzi C, Pecorelli A, Romani A, Belmonte G, Cervellati F, Maioli E, et al. Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells. Free Radic Biol Med. 2018;126:287-295 pubmed publisher
Wang L, Eftekhari P, Schachner D, Ignatova I, Palme V, Schilcher N, et al. Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux. Sci Rep. 2018;8:11061 pubmed publisher
Bruening J, Lasswitz L, Banse P, Kahl S, Marinach C, Vondran F, et al. Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PLoS Pathog. 2018;14:e1007111 pubmed publisher
Zeng Z, Cao B, Guo X, Li W, Li S, Chen J, et al. Apolipoprotein B-100 peptide 210 antibody inhibits atherosclerosis by regulation of macrophages that phagocytize oxidized lipid. Am J Transl Res. 2018;10:1817-1828 pubmed
Tsuzuki S, Kimoto Y, Lee S, Sugawara T, Manabe Y, Inoue K. A novel role for scavenger receptor B1 as a contributor to the capture of specific volatile odorants in the nasal cavity. Biomed Res. 2018;39:117-129 pubmed publisher
Wang D, Hiebl V, Ladurner A, Latkolik S, Bucar F, Heiß E, et al. 6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages. Mol Nutr Food Res. 2018;:e1800011 pubmed publisher
Adamson S, Lin Z, Chen R, Kobos L, Shannahan J. Experimental challenges regarding the in vitro investigation of the nanoparticle-biocorona in disease states. Toxicol In Vitro. 2018;51:40-49 pubmed publisher
Gao F, Li G, Liu C, Gao H, Wang H, Liu W, et al. Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells. J Cell Biol. 2018;217:2103-2119 pubmed publisher
Shannahan J, Sowrirajan H, Persaud I, Podila R, Brown J. Impact of Silver and Iron Nanoparticle Exposure on Cholesterol Uptake by Macrophages. J Nanomater. 2015;2015: pubmed publisher
Durham K, Chathely K, Trigatti B. High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2. Biochem J. 2018;475:1253-1265 pubmed publisher
Schöbel A, Rösch K, Herker E. Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell-derived hepatocytes. Sci Rep. 2018;8:3893 pubmed publisher
Lee S, Heine M, Schlein C, Ramakrishnan R, Liu J, Belnavis G, et al. FoxO transcription factors are required for hepatic HDL cholesterol clearance. J Clin Invest. 2018;128:1615-1626 pubmed publisher
Pewkliang Y, Rungin S, Lerdpanyangam K, Duangmanee A, Kanjanasirirat P, Suthivanich P, et al. A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax. Malar J. 2018;17:50 pubmed publisher
Cartocci V, Catallo M, Tempestilli M, Segatto M, Pfrieger F, Bronzuoli M, et al. Altered Brain Cholesterol/Isoprenoid Metabolism in a Rat Model of Autism Spectrum Disorders. Neuroscience. 2018;372:27-37 pubmed publisher
Milligan S, Martin G, Landrock D, McIntosh A, Mackie J, Schroeder F, et al. Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:323-338 pubmed publisher
Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, et al. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. elife. 2017;6: pubmed publisher
Muresan X, Sticozzi C, Belmonte G, Savelli V, Evelson P, Valacchi G. Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs "in vitro" wound closure. Mech Ageing Dev. 2018;172:78-85 pubmed publisher
Durham K, Chathely K, Mak K, Momen A, Thomas C, Zhao Y, et al. HDL protects against doxorubicin induced cardiotoxicity in a scavenger receptor class B type 1, PI3K, and AKT dependent manner. Am J Physiol Heart Circ Physiol. 2017;:ajpheart.00521.2016 pubmed publisher
Rink J, Yang S, Cen O, Taxter T, McMahon K, Misener S, et al. Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled by Functional Lipoprotein Nanoparticles: A Therapeutic Strategy Dependent on Cell of Origin. Mol Pharm. 2017;14:4042-4051 pubmed publisher
Qian Y, Qiao S, Dai Y, Xu G, Dai B, Lu L, et al. Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages. ACS Nano. 2017;11:9536-9549 pubmed publisher
Pelletier R, Akpovi C, Chen L, Vitale M. Cholesterol metabolism and Cx43, Cx46, Cx50 gap junction protein expression and localisation in normal and diabetic and obese ob/ob and db/db mouse testes. Am J Physiol Endocrinol Metab. 2017;:ajpendo.00215.2017 pubmed publisher
Lai C, Cheng H, Lin C, Huang S, Chen T, Chung C, et al. Activation of liver X receptor suppresses angiogenesis via induction of ApoD. FASEB J. 2017;31:5568-5576 pubmed publisher
Russelli G, Pizzillo P, Iannolo G, Barbera F, Tuzzolino F, Liotta R, et al. HCV replication in gastrointestinal mucosa: Potential extra-hepatic viral reservoir and possible role in HCV infection recurrence after liver transplantation. PLoS ONE. 2017;12:e0181683 pubmed publisher
Fletcher R, Das D, Gadye L, Street K, Baudhuin A, Wagner A, et al. Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution. Cell Stem Cell. 2017;20:817-830.e8 pubmed publisher
Landrock D, Milligan S, Martin G, McIntosh A, Landrock K, Schroeder F, et al. Effect of Fabp1/Scp-2/Scp-x Ablation on Whole Body and Hepatic Phenotype of Phytol-Fed Male Mice. Lipids. 2017;52:385-397 pubmed publisher
Cedó L, Garcia Leon A, Baila Rueda L, Santos D, Grijalva V, Martínez Cignoni M, et al. ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer. Sci Rep. 2016;6:36387 pubmed publisher
Jean Beltran P, Mathias R, Cristea I. A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection. Cell Syst. 2016;3:361-373.e6 pubmed publisher
Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, et al. Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice. J Mol Cell Cardiol. 2016;99:35-46 pubmed publisher
Song G, Wu X, Zhang P, Yu Y, Yang M, Jiao P, et al. High-density lipoprotein inhibits ox-LDL-induced adipokine secretion by upregulating SR-BI expression and suppressing ER Stress pathway. Sci Rep. 2016;6:30889 pubmed publisher
Li J, Wang J, Li M, Yin L, Li X, Zhang T. Up-regulated expression of scavenger receptor class B type 1 (SR-B1) is associated with malignant behaviors and poor prognosis of breast cancer. Pathol Res Pract. 2016;212:555-9 pubmed publisher
Ganesan L, Mates J, Cheplowitz A, Avila C, Zimmerer J, Yao Z, et al. Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells. Sci Rep. 2016;6:20646 pubmed publisher
Hong L, Xu X, Huang J, Lei M, Xu D, Zhao S, et al. Difference in expression patterns of placental cholesterol transporters, ABCA1 and SR-BI, in Meishan and Yorkshire pigs with different placental efficiency. Sci Rep. 2016;6:20503 pubmed publisher
Shi H, Mao X, Zhong Y, Liu Y, Zhao X, Yu K, et al. Lanatoside C Promotes Foam Cell Formation and Atherosclerosis. Sci Rep. 2016;6:20154 pubmed publisher
Ulitzky L, Lafer M, KuKuruga M, Silberstein E, Cehan N, Taylor D. A New Signaling Pathway for HCV Inhibition by Estrogen: GPR30 Activation Leads to Cleavage of Occludin by MMP-9. PLoS ONE. 2016;11:e0145212 pubmed publisher
Cameron S, Morrell C, Bao C, Swaim A, Rodriguez A, Lowenstein C. A Novel Anti-Inflammatory Effect for High Density Lipoprotein. PLoS ONE. 2015;10:e0144372 pubmed publisher
Nadeem A, Thomas P, Ulf M, Elena N, Anggakusuma A, Mohamed B, et al. Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep. 2015;5:18043 pubmed publisher
Bartels E, Christoffersen C, Lindholm M, Nielsen L. Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression. Circ Res. 2015;117:933-42 pubmed publisher
Calattini S, Fusil F, Mancip J, Dao Thi V, Granier C, Gadot N, et al. Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model. J Biol Chem. 2015;290:23173-87 pubmed publisher
Yan X, Shen T, Jiang X, Tang X, Wang D, Li H, et al. Coenzyme Q10 consumption promotes ABCG1-mediated macrophage cholesterol efflux: a randomized, double-blind, placebo-controlled, cross-over study in healthy volunteers. Mol Nutr Food Res. 2015;59:1725-34 pubmed publisher
Sané A, Seidman E, Spahis S, Lamantia V, Garofalo C, Montoudis A, et al. New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis. J Cell Biochem. 2015;116:2270-82 pubmed publisher
Wang Y, Meng C, Wei Q, Shi F, Mao D. Expression and regulation of scavenger receptor class B type 1 in the rat ovary and uterus during the estrous cycle. Acta Histochem. 2015;117:297-304 pubmed publisher
Ng S, Schwartz R, March S, Galstian A, Gural N, Shan J, et al. Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro. Stem Cell Reports. 2015;4:348-59 pubmed publisher
product information
master code :
NB400-104
SKU :
NB400-104
product name :
SR-BI Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The SR-BI Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SR-BI. This antibody reacts with chinese hamster,golden syrian hamster,hamster,human,mouse,mustelid,porcine,primate,rabbit,rat,hamster - cricetulus (chinese hamster). The SR-BI Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,BN,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Knockout Validated,Knockdown Validated,Immunohistochemistry,Flow (Intracellular),Simple Western,Block/Neutralize.
target :
SR-BI
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A C-terminal peptide containing residues from mouse SR-BI (within residues 450-509). [UniProt Q61009]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Chinese Hamster,Golden Syrian Hamster,Hamster,Human,Mouse,Mustelid,Porcine,Primate,Rabbit,Rat,Hamster - Cricetulus (Chinese Hamster)
theoretical molecular weight :
82 kDa
gene symbol :
SCARB1
Antibody validation :
Knockout/Knockdown
accessionNumbers :
Q61009
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,BN,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Knockout Validated,Knockdown Validated,Immunohistochemistry,Flow (Intracellular),Simple Western,Block/Neutralize
USD :
459 USD
alt names :
CD36 and LIMPII analogous 1, CD36 antigen, CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1, CD36L1scavenger receptor class B type 1, CLA1 CD36 antigen-like 1, CLA-1 HDLQTL6, Collagen type I receptor, thrombospondin receptor-like 1, MGC138242, SCARB1, scavenger receptor class B type III, scavenger receptor class B, member 1, SR-B1, SRB1 scavenger receptor class B member 1, SRBI
storage :
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.