SR-BI Antibody - BSA Free | Novus Biologicals NB400-101 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

SR-BI Antibody - BSA Free

catalog :

NB400-101

quantity :

0.1 ml (also 0.025 ml)

price :

479 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 32

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 4c	Tsugita M, Morimoto N, Tashiro M, Kinoshita K, Nakayama M. SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation. Cell Rep. 2017;18:1298-1311 pubmed publisher
western blot; mouse; loading ...; fig s5a	Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher
	Pan X, Hu S, Xu Y, Gopoju R, Zhu Y, Cassim Bawa F, et al. Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways. Metabolism. 2024;155:155909 pubmed publisher
	Velagapudi S, Wang D, Poti F, Feuerborn R, Robert J, Schlumpf E, et al. Sphingosine-1-phosphate receptor 3 regulates the transendothelial transport of high-density lipoproteins and low-density lipoproteins in opposite ways. Cardiovasc Res. 2024;120:476-489 pubmed publisher
	Toutonji A, Krieg C, Borucki D, Mandava M, Guglietta S, Tomlinson S. Mass cytometric analysis of the immune cell landscape after traumatic brain injury elucidates the role of complement and complement receptors in neurologic outcomes. Acta Neuropathol Commun. 2023;11:92 pubmed publisher
	Li Z, He M, Chen G, Worgall T, Jiang X. Effect of Total Sphingomyelin Synthase Activity on Low Density Lipoprotein Catabolism in Mice. bioRxiv. 2023;: pubmed publisher
	May S, Sahoo D. A short amphipathic alpha helix in scavenger receptor BI facilitates bidirectional HDL-cholesterol transport. J Biol Chem. 2022;298:102333 pubmed publisher
	Horlock A, Ormsby T, Clift M, Santos J, Bromfield J, Sheldon I. Cholesterol supports bovine granulosa cell inflammatory responses to lipopolysaccharide. Reproduction. 2022;164:109-123 pubmed publisher
	Zheng K, Kroon J, Schoormans J, Gurney Champion O, Meijer S, Gisbertz S, et al. 89Zr-Labeled High-Density Lipoprotein Nanoparticle PET Imaging Reveals Tumor Uptake in Patients with Esophageal Cancer. J Nucl Med. 2022;63:1880-1886 pubmed publisher
	Shinohata R, Shibakura M, Arao Y, Watanabe S, Hirohata S, Usui S. A high-fat/high-cholesterol diet, but not high-cholesterol alone, increases free cholesterol and apoE-rich HDL serum levels in rats and upregulates hepatic ABCA1 expression. Biochimie. 2022;197:49-58 pubmed publisher
	Dalton G, Oh S, Tang L, Zhang S, Brown A, Varadharajan V, et al. Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice. iScience. 2021;24:103089 pubmed publisher
	Xu H, Thomas M, Kaul S, Kallinger R, Ouweneel A, Maruko E, et al. Pcpe2, a Novel Extracellular Matrix Protein, Regulates Adipocyte SR-BI-Mediated High-Density Lipoprotein Uptake. Arterioscler Thromb Vasc Biol. 2021;41:2708-2725 pubmed publisher
	Baranova I, Bocharov A, Vishnyakova T, Chen Z, Birukova A, Ke Y, et al. Class B Scavenger Receptors BI and BII Protect against LPS-Induced Acute Lung Injury in Mice by Mediating LPS. Infect Immun. 2021;89:e0030121 pubmed publisher
	May S, Dron J, Hegele R, Sahoo D. Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions. J Lipid Res. 2021;62:100045 pubmed publisher
	Xu Y, Li Y, Jadhav K, Pan X, Zhu Y, Hu S, et al. Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism. Nat Metab. 2021;3:59-74 pubmed publisher
	Xu Y, Zhu Y, Hu S, Xu Y, Stroup D, Pan X, et al. Hepatocyte Nuclear Factor 4α Prevents the Steatosis-to-NASH Progression by Regulating p53 and Bile Acid Signaling (in mice). Hepatology. 2021;73:2251-2265 pubmed publisher
	Bouillet B, Gautier T, Denimal D, Samson M, Masson D, Pais de Barros J, et al. Glucocorticoids impair HDL-mediated cholesterol efflux besides increased HDL cholesterol concentration: a proof of concept. Eur J Endocrinol. 2020;183:297-306 pubmed publisher
	Xu Y, Zhu Y, Bawa F, Hu S, Pan X, Yin L, et al. Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice. Hepatol Commun. 2020;4:527-539 pubmed publisher
	Fuenzalida B, Cantin C, Kallol S, Carvajal L, Past xe9 n V, Contreras Duarte S, et al. Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia. Sci Rep. 2020;10:5264 pubmed publisher
	Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed publisher
	Zhu X, Gan Schreier H, Otto A, Cheng Y, Staffer S, Tuma Kellner S, et al. iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:677-687 pubmed publisher
	Toda M, Hellwig M, Henle T, Vieths S. Influence of the Maillard Reaction on the Allergenicity of Food Proteins and the Development of Allergic Inflammation. Curr Allergy Asthma Rep. 2019;19:4 pubmed publisher
	Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018;15:909-912 pubmed publisher
	Pinto P, Da Silva K, Iborra R, Okuda L, Gomes Kjerulf D, Ferreira G, et al. Exercise Training Favorably Modulates Gene and Protein Expression That Regulate Arterial Cholesterol Content in CETP Transgenic Mice. Front Physiol. 2018;9:502 pubmed publisher
	Motherwell J, Anderson C, Murfee W. Endothelial Cell Phenotypes are Maintained During Angiogenesis in Cultured Microvascular Networks. Sci Rep. 2018;8:5887 pubmed publisher
	Baktash Y, Madhav A, Coller K, Randall G. Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process. Cell Host Microbe. 2018;23:382-394.e5 pubmed publisher
	Maddaloni E, Xia Y, Park K, D Eon S, Tinsley L, St Louis R, et al. High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes. Cardiovasc Diabetol. 2017;16:116 pubmed publisher
	Bartelt A, John C, Schaltenberg N, Berbee J, Worthmann A, Cherradi M, et al. Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport. Nat Commun. 2017;8:15010 pubmed publisher
	Garrison C, Lastwika K, Zhang Y, Li C, Lampe P. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity. J Proteome Res. 2017;16:274-287 pubmed publisher
	Baranova I, Souza A, Bocharov A, Vishnyakova T, Hu X, Vaisman B, et al. Human SR-BI and SR-BII Potentiate Lipopolysaccharide-Induced Inflammation and Acute Liver and Kidney Injury in Mice. J Immunol. 2016;196:3135-47 pubmed publisher
	Pasterk L, Lemesch S, Leber B, Trieb M, Curcic S, Stadlbauer V, et al. Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression. Sci Rep. 2016;6:22104 pubmed publisher
	Vaisman B, Vishnyakova T, Freeman L, Amar M, Demosky S, Liu C, et al. Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice. Biomed Res Int. 2015;2015:607120 pubmed publisher

product information

master code :

NB400-101

SKU :

NB400-101

product name :

SR-BI Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The SR-BI Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SR-BI. This antibody reacts with bovine,chinese hamster,human,mouse,mustelid,primate,rat,s. japonicum,hamster - cricetulus (chinese hamster). The SR-BI Antibody - BSA Free has been validated for the following applications: Western Blot,Block/Neutralize,CyTof,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunoblotting,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),Simple Western,Knockout Validated.

target :

SR-BI

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

A C-terminal peptide containing residues from mouse SR-BI (within residues 450-509). [Uniprot: Q61009]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Bovine,Chinese Hamster,Human,Mouse,Mustelid,Primate,Rat,S. japonicum,Hamster - Cricetulus (Chinese Hamster)

theoretical molecular weight :

82 kDa

gene symbol :

SCARB1

Antibody validation :

Knockout/Knockdown

accessionNumbers :

Q8WTV0, Q61009, P97943

applications :

Western Blot,Block/Neutralize,CyTof,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunoblotting,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),Simple Western,Knockout Validated

USD :

479 USD

alt names :

CD36 and LIMPII analogous 1, CD36 antigen, CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1, CD36L1scavenger receptor class B type 1, CLA1 CD36 antigen-like 1, CLA-1 HDLQTL6, Collagen type I receptor, thrombospondin receptor-like 1, MGC138242, SCARB1, scavenger receptor class B type III, scavenger receptor class B, member 1, SR-B1, SRB1 scavenger receptor class B member 1, SRBI

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage