Proprotein Convertase 9/PCSK9 Antibody | Novus Biologicals NB300-959 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Proprotein Convertase 9/PCSK9 Antibody

catalog :

NB300-959

quantity :

0.1 mg

price :

409 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

clone name :

39A1413

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; loading ...; fig 1a	Lebeau P, Byun J, Platko K, Saliba P, Sguazzin M, Macdonald M, et al. Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance. Nat Commun. 2022;13:770 pubmed publisher
	Wen Z, Tang Z, Gu L, Xiang X, Qu Y. Immunomodulatory effect of low molecular-weight seleno-aminopolysaccharide on immunosuppressive mice. Int J Biol Macromol. 2019;123:1278-1288 pubmed publisher
	Tanaka H, Inuzuka K, Iida Y, Shimizu H, Unno N, Urano T. Proprotein Convertase Subtilisin/Kexin Type 9 Is Associated with Degenerating Adipocytes in Abdominal Aortic Aneurysm. J Oleo Sci. 2018;67:1355-1360 pubmed publisher
	Lebeau P, Platko K, Al Hashimi A, Byun J, Lhotak S, Holzapfel N, et al. Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. J Biol Chem. 2018;293:7329-7343 pubmed publisher
	Kanno Y, Maruyama C, Matsuda A, Ishisaki A. uPA-derived peptide, Å6 is involved in the suppression of lipopolysaccaride-promoted inflammatory osteoclastogenesis and the resultant bone loss. Immun Inflamm Dis. 2017;5:289-299 pubmed publisher
	Gu L, Wen Z, Xiang X, Ma L, Wang X, Ma J, et al. Immunomodulatory effect of low molecular-weight seleno-aminopolysaccharides in intestinal epithelial cells. Int J Biol Macromol. 2017;99:570-577 pubmed publisher
	Lebeau P, Al Hashimi A, Sood S, Lhotak S, Yu P, Gyulay G, et al. Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. J Biol Chem. 2017;292:1510-1523 pubmed publisher
	Samanta D, Gilkes D, Chaturvedi P, Xiang L, Semenza G. Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc Natl Acad Sci U S A. 2014;111:E5429-38 pubmed publisher
	Das U, Manna K, Sinha M, Datta S, Das D, Chakraborty A, et al. Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model. PLoS ONE. 2014;9:e97599 pubmed publisher
	Shakibaei M, Allaway D, Nebrich S, Mobasheri A. Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1?-Induced NF-?B Activation in Canine Articular Chondrocytes. Evid Based Complement Alternat Med. 2012;2012:509383 pubmed publisher
	Li Q, Guo Y, Tan W, Ou Q, Wu W, Sturza D, et al. Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway. Circulation. 2007;116:1577-84 pubmed
	Yang M, Hase H, Legarda Addison D, Varughese L, Seed B, Ting A. B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. J Immunol. 2005;175:2814-24 pubmed
	Jazirehi A, Huerta Yepez S, Cheng G, Bonavida B. Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis. Cancer Res. 2005;65:264-76 pubmed
	Lotz S, Aga E, Wilde I, van Zandbergen G, Hartung T, Solbach W, et al. Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2. J Leukoc Biol. 2004;75:467-77 pubmed
	Ikezoe T, Yang Y, Heber D, Taguchi H, Koeffler H. PC-SPES: a potent inhibitor of nuclear factor-kappa B rescues mice from lipopolysaccharide-induced septic shock. Mol Pharmacol. 2003;64:1521-9 pubmed
	Han H, Karabiyikoglu M, Kelly S, Sobel R, Yenari M. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab. 2003;23:589-98 pubmed

product information

master code :

NB300-959

SKU :

NB300-959

product name :

Proprotein Convertase 9/PCSK9 Antibody

unit size :

0.1 mg

description :

The Proprotein Convertase 9/PCSK9 Antibody from Novus is a goat polyclonal antibody to Proprotein Convertase 9/PCSK9. This antibody reacts with human,mouse. The Proprotein Convertase 9/PCSK9 Antibody has been validated for the following applications: Chemotaxis,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Peptide ELISA,Chromatin Immunoprecipitation (ChIP).

target :

Proprotein Convertase 9/PCSK9

category :

Primary Antibodies

buffer :

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

clonality :

Polyclonal

concentration :

0.5 mg/ml

conjugate :

Unconjugated

host :

Goat

immunogen :

Peptide with sequence CRSRHLAQASQELQ corresponding to C-Terminus according to NP_777596.2.

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse

gene symbol :

PCSK9

accessionNumbers :

Q8NBP7

applications :

Chemotaxis,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Peptide ELISA,Chromatin Immunoprecipitation (ChIP)

USD :

409 USD

alt names :

EC 3.4.21, EC 3.4.21.111, FH3neural apoptosis regulated convertase 1, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC-1convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage