product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GR/NR3C1 Antibody (BuGR2) - BSA Free
catalog :
NB300-731
quantity :
100 ug
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BuGR2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig s12c
Rue L, Bañez Coronel M, Creus Muncunill J, Giralt A, Alcalá Vida R, Mentxaka G, et al. Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels. J Clin Invest. 2016;126:4319-4330 pubmed publisher
Rudak P, Choi J, Parkins K, Summers K, Jackson D, Foster P, et al. Chronic stress physically spares but functionally impairs innate-like invariant T cells. Cell Rep. 2021;35:108979 pubmed publisher
Adams R, Smith C. In utero Exposure to Maternal Chronic Inflammation Transfers a Pro-Inflammatory Profile to Generation F2 via Sex-Specific Mechanisms. Front Immunol. 2020;11:48 pubmed publisher
Adams R, Smith C. Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny. Mediators Inflamm. 2019;2019:9160941 pubmed publisher
Taves M, Mittelstadt P, Presman D, Hager G, Ashwell J. Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus. Cell Rep. 2019;26:3629-3642.e4 pubmed publisher
Roh K, Park D, Jung E. Inhibitory Effects of Prunella vulgaris L. Extract on 11β-HSD1 in Human Skin Cells. Evid Based Complement Alternat Med. 2018;2018:1762478 pubmed publisher
Yang X, Chen S, Shao Z, Li Y, Wu H, Li X, et al. Apolipoprotein E Deficiency Exacerbates Spinal Cord Injury in Mice: Inflammatory Response and Oxidative Stress Mediated by NF-κB Signaling Pathway. Front Cell Neurosci. 2018;12:142 pubmed publisher
Chen Y, Chen L, Yeh Y, Wu P, Chen Y, Chang L, et al. Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy. Sci Rep. 2017;7:45366 pubmed publisher
Wu J, Pinello L, Yissachar E, Wischhusen J, Yuan G, Roberts C. Functionally distinct patterns of nucleosome remodeling at enhancers in glucocorticoid-treated acute lymphoblastic leukemia. Epigenetics Chromatin. 2015;8:53 pubmed publisher
Schoenfelder Y, Hiemke C, Schmitt U. Behavioural consequences of p-glycoprotein deficiency in mice, with special focus on stress-related mechanisms. J Neuroendocrinol. 2012;24:809-17 pubmed publisher
Harrell J, Murphy P, Morishima Y, Chen H, Mansfield J, Galigniana M, et al. Evidence for glucocorticoid receptor transport on microtubules by dynein. J Biol Chem. 2004;279:54647-54 pubmed
Viegas L, Vicent G, Barañao J, Beato M, Pecci A. Steroid hormones induce bcl-X gene expression through direct activation of distal promoter P4. J Biol Chem. 2004;279:9831-9 pubmed
Kanters E, Pasparakis M, Gijbels M, Vergouwe M, Partouns Hendriks I, Fijneman R, et al. Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2003;112:1176-85 pubmed
te Velde E, Kusters B, Maass C, De Waal R, Borel Rinkes I. Histological analysis of defective colonic healing as a result of angiostatin treatment. Exp Mol Pathol. 2003;75:119-23 pubmed
Linehan S, Coulson P, Wilson R, Mountford A, Brombacher F, Martinez Pomares L, et al. IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni. Lab Invest. 2003;83:1223-31 pubmed
Simonen M, Pedersen V, Weinmann O, Schnell L, Buss A, Ledermann B, et al. Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury. Neuron. 2003;38:201-11 pubmed
Lambert J, Nordeen S. CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins. Mol Endocrinol. 2003;17:1085-94 pubmed
Morioka J, Kajiwara K, Yoshikawa K, Ideguchi M, Uchida T, Ohmoto Y, et al. Adenovirus-mediated gene transfer of B7.1 induces immunological anti-tumor effects in a murine brain tumor. J Neurooncol. 2002;60:13-23 pubmed
Sasaki A, Shoji M, Harigaya Y, Kawarabayashi T, Ikeda M, Naito M, et al. Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites. Virchows Arch. 2002;441:358-67 pubmed
Courret N, Frehel C, Gouhier N, Pouchelet M, Prina E, Roux P, et al. Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites. J Cell Sci. 2002;115:2303-16 pubmed
McLellan A, Kapp M, Eggert A, Linden C, Bommhardt U, Brocker E, et al. Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression. Blood. 2002;99:2084-93 pubmed
Mueller C, Cremer I, Paulet P, Niida S, Maeda N, Lebeque S, et al. Mannose receptor ligand-positive cells express the metalloprotease decysin in the B cell follicle. J Immunol. 2001;167:5052-60 pubmed
Guenther K, Deacon R, Perry V, Rawlins J. Early behavioural changes in scrapie-affected mice and the influence of dapsone. Eur J Neurosci. 2001;14:401-9 pubmed
Gough P, Gordon S, Greaves D. The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo. Immunology. 2001;103:351-61 pubmed
Linehan S, Martinez Pomares L, da Silva R, Gordon S. Endogenous ligands of carbohydrate recognition domains of the mannose receptor in murine macrophages, endothelial cells and secretory cells; potential relevance to inflammation and immunity. Eur J Immunol. 2001;31:1857-66 pubmed
Hemmi H, Yoshino M, Yamazaki H, Naito M, Iyoda T, Omatsu Y, et al. Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells. Int Immunol. 2001;13:695-704 pubmed
Uchida T, Kajiwara K, Ideguchi M, Yoshikawa K, Morioka J, Suzuki M. Co-administration of adenovirus vector expressing CTLA4-Ig prolongs transgene expression in the brain of mice sensitized with adenovirus. Brain Res. 2001;898:272-80 pubmed
Walsh D, Betmouni S, Perry V. Absence of detectable IL-1beta production in murine prion disease: a model of chronic neurodegeneration. J Neuropathol Exp Neurol. 2001;60:173-82 pubmed
Lang T, Ave P, Huerre M, Milon G, Antoine J. Macrophage subsets harbouring Leishmania donovani in spleens of infected BALB/c mice: localization and characterization. Cell Microbiol. 2000;2:415-30 pubmed
Bornemann K, Wiederhold K, Pauli C, Ermini F, Stalder M, Schnell L, et al. Abeta-induced inflammatory processes in microglia cells of APP23 transgenic mice. Am J Pathol. 2001;158:63-73 pubmed
Aramaki Y. Liposomes as immunomodulator--inhibitory effect of liposomes on NO production from macrophages. Biol Pharm Bull. 2000;23:1267-74 pubmed
Scott C, Roe L, Curtis J, Baldwin T, Robb L, Begley C, et al. Mice unresponsive to GM-CSF are unexpectedly resistant to cutaneous Leishmania major infection. Microbes Infect. 2000;2:1131-8 pubmed
Yoshikawa K, Kajiwara K, Ideguchi M, Uchida T, Ito H. Immune gene therapy of experimental mouse brain tumor with adenovirus-mediated gene transfer of murine interleukin-4. Cancer Immunol Immunother. 2000;49:23-33 pubmed
Shinomiya M, Nadano S, Shinomiya H, Onji M. In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis. Pancreas. 2000;20:290-6 pubmed
Van der Hoek K, Maddocks S, Woodhouse C, van Rooijen N, Robertson S, Norman R. Intrabursal injection of clodronate liposomes causes macrophage depletion and inhibits ovulation in the mouse ovary. Biol Reprod. 2000;62:1059-66 pubmed
Robertson S, O Connell A, Hudson S, Seamark R. Granulocyte-macrophage colony-stimulating factor (GM-CSF) targets myeloid leukocytes in the uterus during the post-mating inflammatory response in mice. J Reprod Immunol. 2000;46:131-54 pubmed
product information
master code :
NB300-731
SKU :
NB300-731
product name :
GR/NR3C1 Antibody (BuGR2) - BSA Free
unit size :
100 ug
description :
The GR/NR3C1 Antibody (BuGR2) - BSA Free from Novus is a mouse monoclonal antibody to GR/NR3C1. This antibody reacts with guinea pig,human,mouse,rabbit,rat,sheep,yeast. The GR/NR3C1 Antibody (BuGR2) - BSA Free has been validated for the following applications: Chemotaxis,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Gel Super Shift Assays,Chromatin Immunoprecipitation (ChIP),Block/Neutralize.
target :
GR/NR3C1
category :
Primary Antibodies
buffer :
PBS (pH 7.2)
clonality :
Monoclonal
clone :
BuGR2
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Partially purified rat GR.
isotype :
IgG2a
purity :
Protein A purified
species :
Guinea Pig,Human,Mouse,Rabbit,Rat,Sheep,Yeast
specificity :
Using enzymatic digestion analysis, has been shown to react with the undigested 97 kDa GR, a 17 kDa DNA-binding trypsin fragment, and a 45 kDa steroid- and DNA-binding chymotrypsin fragment
gene symbol :
NR3C1
applications :
Chemotaxis,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Gel Super Shift Assays,Chromatin Immunoprecipitation (ChIP),Block/Neutralize
USD :
409 USD
alt names :
GCR, glucocorticoid receptor, GRGCCR, GRLNuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.