product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
O-GlcNAc Antibody (HGAC85)
catalog :
NB300-614
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HGAC85
reactivity :
primate, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; primate
Yagi H, Nakagawa N, Saito T, Kiyonari H, Abe T, Toda T, et al. AGO61-dependent GlcNAc modification primes the formation of functional glycans on ?-dystroglycan. Sci Rep. 2013;3:3288 pubmed publisher
  • immunocytochemistry; rat
Akimoto Y, Kreppel L, Hirano H, Hart G. Localization of the O-linked N-acetylglucosamine transferase in rat pancreas. Diabetes. 1999;48:2407-13 pubmed
  • immunocytochemistry; rat
Turner J, Tartakoff A, Greenspan N. Cytologic assessment of nuclear and cytoplasmic O-linked N-acetylglucosamine distribution by using anti-streptococcal monoclonal antibodies. Proc Natl Acad Sci U S A. 1990;87:5608-12 pubmed
Akinbiyi E, Abramowitz L, Bauer B, Stoll M, Hoppel C, Hsiao C, et al. Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass. Sci Rep. 2021;11:22106 pubmed publisher
Tordjman J, Majumder M, Amiri M, Hasan A, Hess D, Lala P. Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells. BMC Cancer. 2019;19:561 pubmed publisher
Ishimura E, Nakagawa T, Moriwaki K, Hirano S, Matsumori Y, Asahi M. Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line. Cancer Sci. 2017;: pubmed publisher
Bimonte S, Barbieri A, Rea D, Palma G, Luciano A, Cuomo A, et al. Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression. Biomed Res Int. 2015;2015:161508 pubmed publisher
Samaga K, Rao G, Chandrashekara Reddy G, Kush A, Diwakar L. Synthetic racemates of abyssinone I and II induces apoptosis through mitochondrial pathway in human cervix carcinoma cells. Bioorg Chem. 2014;56:54-61 pubmed publisher
Love D, Ghosh S, Mondoux M, Fukushige T, Wang P, Wilson M, et al. Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity. Proc Natl Acad Sci U S A. 2010;107:7413-8 pubmed publisher
Hamiel C, Pinto S, Hau A, Wischmeyer P. Glutamine enhances heat shock protein 70 expression via increased hexosamine biosynthetic pathway activity. Am J Physiol Cell Physiol. 2009;297:C1509-19 pubmed publisher
Zhang X, Bennett V. Identification of O-linked N-acetylglucosamine modification of ankyrinG isoforms targeted to nodes of Ranvier. J Biol Chem. 1996;271:31391-8 pubmed
Greenspan N, Dacek D, Cooper L. Fc region-dependence of IgG3 anti-streptococcal group A carbohydrate antibody functional affinity. I. The effect of temperature. J Immunol. 1988;141:4276-82 pubmed
Greenspan N, Dacek D, Cooper L. Cooperative binding of two antibodies to independent antigens by an Fc-dependent mechanism. FASEB J. 1989;3:2203-7 pubmed
Greenspan N, Monafo W, Davie J. Interaction of IgG3 anti-streptococcal group A carbohydrate (GAC) antibody with streptococcal group A vaccine: enhancing and inhibiting effects of anti-GAC, anti-isotypic, and anti-idiotypic antibodies. J Immunol. 1987;138:285-92 pubmed
product information
master code :
NB300-614
SKU :
NB300-614
product name :
O-GlcNAc Antibody (HGAC85)
unit size :
0.1 ml (also 0.025 ml)
description :
The O-GlcNAc Antibody (HGAC85) - BSA Free from Novus is a mouse monoclonal antibody to O-GlcNAc. This antibody reacts with all species,human,mouse,primate,rat. The O-GlcNAc Antibody (HGAC85) - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Western Blot,Chromatin Immunoprecipitation,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP).
target :
O-GlcNAc
category :
Primary Antibodies
buffer :
Ascites
clonality :
Monoclonal
clone :
HGAC85
conjugate :
Unconjugated
host :
Mouse
immunogen :
Heat-killed, pepsin-treated group A streptococci (Streptococcus pyogenes)
isotype :
IgG3 Kappa
purity :
Unpurified
species :
All Species,Human,Mouse,Primate,Rat
specificity :
Recognizes beta-1,3 linked O-linked N-acetylglucosamine (O-GlcNAc) residues of streptococcal group A carbohydrate as well as O-GlcNAc glycosylated proteins
Antibody validation :
Biological Validation
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP)
USD :
409 USD
alt names :
GlcNAc, O-linked N-acetylglucosamine
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.