product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
LXR alpha/NR1H3 Antibody
catalog :
NB300-612
quantity :
200 ug (also 50 ug)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
22B1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, EMSA
more info or order :
citations: 7
Reference
Palma G, Kaur M. miRNA-128 and miRNA-223 regulate cholesterol-mediated drug resistance in breast cancer. IUBMB Life. 2023;75:743-764 pubmed publisher
Rudalska R, Harbig J, Snaebjornsson M, Klotz S, Zwirner S, Taranets L, et al. LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer. Nat Cancer. 2021;2:201-217 pubmed publisher
Bruschi F, Claudel T, Tardelli M, Starlinger P, Marra F, Trauner M. PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells. Hepatol Commun. 2019;3:1191-1204 pubmed publisher
Cai B, Kasikara C, Doran A, Ramakrishnan R, Birge R, Tabas I. MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. Sci Signal. 2018;11: pubmed publisher
Ersoy B, Maner Smith K, Li Y, Alpertunga I, Cohen D. Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress. J Clin Invest. 2018;128:141-156 pubmed publisher
Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher
Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, et al. Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/?-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria. J Biol Chem. 2013;288:23368-79 pubmed publisher
product information
master code :
NB300-612
SKU :
NB300-612
product name :
LXR alpha/NR1H3 Antibody
unit size :
200 ug (also 50 ug)
description :
The LXR alpha/NR1H3 Antibody from Novus is a rabbit polyclonal antibody to LXR alpha/NR1H3. This antibody reacts with human,mouse. The LXR alpha/NR1H3 Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunohistochemistry,Gel Super Shift Assays,Immunocytochemistry/ Immunofluorescence.
target :
LXR alpha/NR1H3
category :
Primary Antibodies
buffer :
PBS with 1 mg/ml BSA
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide corresponding to residues C D(318) F S Y N R E D F A K A(329) of human LXR alpha.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
specificity :
Detects recombinant human LXR alpha
gene symbol :
NR1H3
applications :
Western Blot,Flow Cytometry,Immunohistochemistry,Gel Super Shift Assays,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
alpha, Liver X receptor alpha, liver X receptor-alpha, LXRA, Nuclear receptor subfamily 1 group H member 3, nuclear receptor subfamily 1, group H, member 3, oxysterols receptor LXR-alpha, RLD-1
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.